Cyclosporin

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

IschemiaMembranous Nephropathy

47 competitors in Ischemia

#DrugCompanyPhaseTrials

1

Crestor

AstraZeneca

Approved

22

Repatha

Amgen

Approved

13

Lovenox

Sanofi

Approved

14

Corlanor

Amgen

Approved

15

Bayer Aspirin

Bayer

Approved

—6

Remodulin

United Therapeutics

Approved

—7

Taxol

Teva

Approved

—8

Persantine

Boehringer Ingelheim

Approved

29

Lipitor

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

210

Caverject

VViatris Specialty LLC

Approved

1Show 29 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Membranous Nephropathy2 trials

A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.

Recruiting·SShanghai Jiaolian Drug Research and Development Co., Ltd·Phase 2/3·NCT06470191·216 enrolled

A Study to Learn More About the Effects and Safety of JMT601 in Adults With Primary Membranous Nephropathy

Not yet recruiting·SShanghai JMT-Bio Inc.·Phase 2·NCT07029139·156 enrolled

Kidney Transplant1 trial

Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM)

Completed·SStanford University·Phase 4·NCT00296296·29 enrolled

Liver Transplant1 trial

Sustained Virological Response (SVR) to Antiviral Treatment of Liver Transplant Recipients With Recurrent Hepatitis C

Completed·Novartis·Phase 4·NCT00938860·92 enrolled

Alopecia Areata1 trial

Cyclosporine Or Methotrexate for Pediatric Alopecia Areata: Routine Clinical Care Effectiveness Study

Recruiting·EErasmus Medical Center·Phase 4·NCT07381556·50 enrolled

Psoriasis1 trial

Combined Use of Cyclosporine and Metformin in Treatment of Psoriasis vs Cyclosporine Alone

Completed·—·Phase 1·NCT07375654·32 enrolled

12 more indications

Tacrolimus1 trial

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Completed·AstraZeneca·Phase 1·NCT04788641·62 enrolled

Sjögren Syndrome1 trial

Effect of Ciclosporin Eyedrops on Sjögren Syndrome

Completed·HHospital Hietzing·N/A·NCT04597762·12 enrolled

Membranoproliferative Glomerulonephritis1 trial

Effect of Rituximab in Treatment of Membranoproliferative Glomerulonephritis

Unknown status·—·Phase 3·NCT03180723·30 enrolled

Eye Disease1 trial

Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease

Terminated·UUniversity of Missouri-Columbia·Phase 2·NCT01072526·7 enrolled

Lymphoma1 trial

Reduced-Intensity Regimen Before Allogeneic Transplant for Patients With Relapsed Non-Hodgkin's or Hodgkin's Lymphoma

Terminated·EEastern Cooperative Oncology Group·Phase 2·NCT00057954·6 enrolled

Stem Cell Transplantation1 trial

Stem Cell Transplantation for Metastatic Solid Tumors

Terminated·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 2·NCT00001880·42 enrolled

Ischemia1 trial

Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery

Completed·IIndonesia University·N/A·NCT05691764·40 enrolled

Bone Marrow Transplantation1 trial

Treatment of Severe Osteogenesis Imperfecta by Allogeneic Bone Marrow Transplantation

Completed·SSt. Jude Children's Research Hospital·Phase 1·NCT00705120·9 enrolled

Histiocytosis1 trial

Treatment Protocol for Hemophagocytic Lymphohistiocytosis 2004

Completed·KKarolinska University Hospital·Phase 3·NCT00426101·368 enrolled

Glomerulosclerosis, Focal1 trial

Focal Segmental Glomerulosclerosis Clinical Trial

Completed·NNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 3·NCT00135811·192 enrolled

Type 1 Diabetes1 trial

Clinical and Biological Responses to Repeated Administration of Low-dose Interleukin-2 in Patients With Type 1 Diabetes and a Residual Insulin Secretion

Recruiting·AAssistance Publique - Hôpitaux de Paris·Phase 2·NCT05153070·24 enrolled

Dry Eye Disease (DED)1 trial

A Non-interventional Study to Evaluate the Anti-inflammatory Effects and the Clinical Efficacy of Topical Water Free Cyclosporin 0.1% Eye Drops in Patients With Dry Eye Disease and Associated Ocular Surface Inflammation Non-responding to Artificial Tears: the FOCUS Study

Completed·LLaboratoires Thea··NCT07234318·25 enrolled

Details

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