Dalalone
(Dexamethasone acetate)PreclinicalSmall molecule
Dexamethasone acetate is a corticosteroid used to reduce inflammation and suppress the immune system in conditions like swelling, allergic reactions, and autoimmune disorders. It's also used to manage symptoms of certain cancers and to prevent nausea from chemotherapy.[1] Dalalone is currently being investigated across 4 indications[3], with its most advanced program in Preclinical.[1]
Dalalone is one of 54 small molecule programs targeting Cognition. It is currently in Preclinical.
4
Indications
20
Total Trials
0
Active Trials
53
Competitors
Pipeline
Status by Indication[3][1]
Competition
Competitive Landscape
85 competitors in Cognition
#DrugCompanyPhaseTrials
1Ambien
PPurdue Pharma LP
Approved
Prometrium
FerringApproved
Xarelto
WWim Janssens
Approved
Neurontin
VViatris Specialty LLC
Approved
Osmitrol
BB. Braun Medical Inc.
Approved
Zanaflex
LLegacy Health System
Approved
Namenda
AbbViePhase 3
Nuplazid
AACADIA Pharmaceuticals Inc.
Phase 2
Remimazolam Tosilate
FFujian Shengdi Pharmaceutical Co., Ltd.
Phase 3
Psilocybin
COMPASS PathwaysPhase 2
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Clinical
Trials by Indication[1]
Acute Lymphoblastic Leukemia2 trials
Multiple Myeloma1 trial
Third Molar Surgery1 trial
Acute Pancreatitis1 trial
Early Treatment With Dexamethasone in Mild Acute Pancreatitis
Withdrawn·—·Phase 2·NCT01247961
Cryotherapy1 trial
Interest of Cryotherapy or Cortisone Aerosol Therapy in Early Post-operative Swallowing Disorders Following Total Thyroidectomy
Completed·—·N/A·NCT02855866·240 enrolled
14 more indications
Bone Metastases1 trial
Lymphoma1 trial
A Pilot Study of Oncaspar® + Dexamethasone in Patients With Relapsed or Refractory T-Cell Lymphoma
Terminated·—·Phase 1·NCT01878708·2 enrolled
Cognition1 trial
Effects of Steroid Tapering on Functional Capacity and Neurocognition
Withdrawn·—·N/A·NCT01169415
Complication1 trial
Meningitis1 trial
Neuroblastoma1 trial
Peripheral Nerve Block1 trial
Analgesic Efficacy1 trial
Dexamethasone1 trial
Mitoxantrone Hydrochloride Liposome Injection, Bortezomib and Dexamethasone in the Treatment of R/R MM
Unknown status·CCSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.·Phase 1·NCT05052970·60 enrolled
Lenalidomide1 trial
Femur Fracture1 trial
Single Dose of Dexamethasone in Femur Fractures
Unknown status·—·Phase 4·NCT01550146·40 enrolled
Relapsed or Refractory1 trial
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Dexamethasone acetate. EMBL-EBI & Wellcome Sanger Institute.
- [4]
Details