dexketoprofen trometamol

PreclinicalSmall molecule

Menarini

dexketoprofen trometamol is one of 111 small molecule programs targeting Dysmenorrhea. It is currently in Preclinical.

Indications

Total Trials

Active Trials

110

Competitors

Pipeline

Status by Indication[3][1]

Indication

DysmenorrheaActive, not recruiting

AnxietyActive, not recruiting

MigraineActive, not recruiting

TramadolCompleted

Multimodal AnalgesiaUnknown status

AnalgesicCompleted

DysmenorrheaPreclinical

Active, not recruiting

AnxietyPreclinical

Active, not recruiting

MigrainePreclinical

Active, not recruiting

TramadolPreclinical

Completed

Multimodal AnalgesiaPreclinical

Unknown status

AnalgesicPreclinical

Completed

Competition

Competitive Landscape

105 competitors in Migraine

#DrugCompanyPhaseTrials

Zonegran

AAzurity Pharmaceuticals

Phase 3

3 2

Triptans

Pfizer

Phase 3

2 3

Aspirin /d

TThe First Affiliated Hospital with Nanjing Medical University

Phase 3

1 4

Elismetrep

KKallyope Inc.

Phase 3

3 5

Flunarizine

AAspartes Pharmaceuticals, Inc.

Phase 3

9 6

Tizanidine Hydrochloride

EElan Pharmaceuticals

Phase 3

1 7

Bayer Aspirin

Bayer

Preclinical

2 8

Cervidil

Pfizer

Preclinical

1 9

Cymbalta

Jazz Pharmaceuticals

Preclinical

1 10

Adempas

Bayer

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Post-ApprovalNot yet recruiting

Renal Colic

NCT07176572

Clinical

Trials by Indication[1]

Renal Colic3 trials

Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation and Dexketoprofen in Renal Colic

Not yet recruiting·—·Phase 4·NCT07176572·128 enrolled

Analgesic Effect of Erector Spinae Plane Block for Renal Colic Pain

Completed·—·Phase 4·NCT04209439·40 enrolled

Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol, Meperidine, and Paracetamol in Renal Colic

Completed·IIsmail Tekin·Phase 4·NCT06558916·90 enrolled

Third Molar Surgery2 trials

Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?

Completed·TTokat Gaziosmanpasa University·Phase 4·NCT04200885·52 enrolled

Analgesic Preoperative/Postoperative Dexketoprofen Trometamol in Third Molar Surgery

Completed·DDaniel Chavarría Bolaños·Phase 4·NCT02380001·60 enrolled

Pain2 trials

Pain and Suction Curettage

Completed·GGökhan Açmaz·N/A·NCT01947205·111 enrolled

Dexketoprofen Trometamol in Postoperative Endodontic Pain

Completed·DDaniel Chavarría Bolaños·Phase 4·NCT02086097·90 enrolled

Hysterectomy1 trial

Comparison of Preemptive Analgesic Effects of Dexketoprofen Versus Dexmedetomidine on Abdominal Hysterectomy Patients

Unknown status·TTC Erciyes University·Phase 4·NCT02092012·60 enrolled

Analgesic Efficacy1 trial

Comparison of Postoperative Analgesic Efficacy of Intravenous Dexketoprofen Trometamol With Tenoxicam

Unknown status·TTC Erciyes University·Phase 4·NCT02160236·90 enrolled

12 more indications

Dental Implant1 trial

Preventive Treatment of Pain After Dental Implant Surgery

Completed·UUniversidad de Murcia·Phase 4·NCT03107338·100 enrolled

Severe Pain1 trial

Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain

Completed· Menarini logo

Menarini·Phase 2·NCT01307020·745 enrolled

Analgesic1 trial

Analgesic Use for Pain Relief in Scorpion Sting

Completed·—·N/A·NCT05125796·106 enrolled

Postoperative Pain Management1 trial

Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication

Unknown status·KKavaklıdere Umut Hospital·Phase 4·NCT01558622·72 enrolled

Anxiety1 trial

Determination of the Effects of Change in Anxiety Level on Pain Perception in Patients Who Present to Emergency Department

Completed·—·N/A·NCT03420911·180 enrolled

Dysmenorrhea1 trial

Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary Dysmenorrhea

Unknown status·PPamukkale University·N/A·NCT03697746·300 enrolled

Temporomandibular Disorder1 trial

Evaluation of the Efficacy of Different Drugs in the Treatment of the Pain in Patients With Temporomandibular Disorder

Completed·YYuzuncu Yil University·Phase 4·NCT05529290·200 enrolled

Multimodal Analgesia1 trial

Multimodal Analgesia Methods in Patients Undergoing IPACK Block in Knee Arthroplasty

Unknown status·—·N/A·NCT04213287·70 enrolled

Total Knee Arthroplasty1 trial

Evaluation of Dexketoprofen in Total Knee Arthroplasty

Unknown status·KKAT General Hospital·Phase 2·NCT04161690·120 enrolled

Tramadol1 trial

Short-term Perfusion Effects: Dexketoprofen/Tramadol

Completed·—·N/A·NCT07386288·102 enrolled

Migraine1 trial

Intravenous Metoclopramide Versus Dexketoprofen Trometamol Versus Metoclopramide+ Dexketoprofen Trometamol in Migraine

Completed·—·N/A·NCT04252521·150 enrolled

Fracture1 trial

Analgesic Efficacy of a Naproxen and Lidocaine Gel Combination in Patients With Traumatic Rib Fractures: A Randomized Controlled Trial

Completed·AAnkara City Hospital Bilkent·Preclinical·NCT07706036·110 enrolled

Sources

References

[1]
ClinicalTrials.gov — 21 trial records for dexketoprofen trometamol. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — dexketoprofen trometamol compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for dexketoprofen trometamol. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Menarini company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: Menarini

dexketoprofen trometamol

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Trials by Indication[1]

Renal Colic3 trials

Third Molar Surgery2 trials

Pain2 trials

Hysterectomy1 trial

Analgesic Efficacy1 trial

Dental Implant1 trial

Severe Pain1 trial

Analgesic1 trial

Postoperative Pain Management1 trial

Anxiety1 trial

Dysmenorrhea1 trial

Temporomandibular Disorder1 trial

Multimodal Analgesia1 trial

Total Knee Arthroplasty1 trial

Tramadol1 trial

Migraine1 trial

Fracture1 trial

References

Drug Info

Quick Facts

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