Dexmedetomidine 5 micrograms

PreclinicalSmall molecule

UUdayana University

Dexmedetomidine 5 micrograms is one of 44 small molecule programs targeting Glaucoma. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

GlaucomaActive, not recruiting

Spinal AnesthesiaUnknown status

GlaucomaPreclinical

Active, not recruiting

Spinal AnesthesiaPreclinical

Unknown status

Competition

Competitive Landscape

54 competitors in Glaucoma

#DrugCompanyPhaseTrials

Alphagan

Novartis

Approved

3 2

Zolymbus

AbbVie

Approved

3 3

Travatan

Novartis

Approved

3 4

Xalatan

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

10 5

Timolol Maleate

CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Approved

9 6

Diamox

Teva

Approved

1 7

Crestor

AstraZeneca

Approved

1 8

Neoral

Isopto Carpine

1 10

Flovent

PParatek Pharmaceuticals Inc

Approved

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Dexmedetomidine6 trials

Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy

Completed·UUdayana University·Phase 4·NCT07292324·62 enrolled

Dexmedetomidine vs Ketamine as Adjuvants to Bupivacaine in Transversus Abdominus Plane Block in Inguinal Hernioplasty

Completed·—·Phase 3·NCT07194694·60 enrolled

Dexmedetomidine for Prophylaxis Against PONV in Highly Susceptible Patients.

Completed·—·N/A·NCT05134363·180 enrolled

Show 3 more trials

COMPARISON OF BUPIVACAINE WITH AND WITHOUT DEXMEDETOMIDINE IN CAUDAL BLOCK AMONG CHILDREN UNDERGOING INGUINAL HERNIOTOMY

Completed·—·Phase 1·NCT07140627·60 enrolled

Lidocaine 5% Patch Supplementation to Intra-articular Bupivacaine Dexmedetomidine After Arthroscopic Knee Surgery

Completed·TTanta University·N/A·NCT04322760·40 enrolled

Peri-neural Dexmedetomidine as an Adjuvant to Bupivacaine Induced Paravertebral Block in Patients Undergonig Thoracotomy

Completed·—·Phase 2·NCT02397603·40 enrolled

Cesarean Section1 trial

Intrathecal Dexmedetomidine With Bupivacaine for Spinal Anesthesia in Cesarean Section

Completed·—·Phase 4·NCT02365857·120 enrolled

Postoperative Pain Relief1 trial

Postoperative Pain Relief in Children: Comparing Caudal Bupivacaine Alone Versus Bupivacaine With Dexmedetomidine for Infra-Umbilical Surgeries Under General Anesthesia

Completed·—·Phase 4·NCT07121764·60 enrolled

Opioid Free Anesthesia1 trial

Multimodal Opioid-free Anesthesia Versus Opioid-based Anesthesia for Patients Undergoing Cardiac Valve Surgeries: RCT

Completed·—·Phase 1·NCT04648540·60 enrolled

Superficial Cervical Plexus Block1 trial

Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery

Completed·UUdayana University·N/A·NCT07274670·58 enrolled

7 more indications

Magnesium Sulfate1 trial

Magnesium Sulfate in Combination With Dexmedetomidine As Adjuvants to Levobupivacaine

Completed·—·Phase 1·NCT04498351·130 enrolled

Intracranial Pressure1 trial

Adding Dexmedetomidine to Mannitol to Attenuate the Increase of Intracranial Pressure

Completed·—·Phase 2/3·NCT07064720·60 enrolled

Glaucoma1 trial

Dexmedetomidine as an Additive to Local Anaesthesia to Decrease Intraocular Pressure in Glaucoma Surgery

Unknown status·—·N/A·NCT02846090·105 enrolled

Quadratus Lumborum Block1 trial

Dexmedetomidine Added to Bupivacaine Versus Bupivacaine inTransincisionalU/S Guided Quadratus Lumborum Block in Open Renal Surgeries , A New Technique

Completed·—·Phase 4·NCT03869047·80 enrolled

Perioperative Analgesia1 trial

Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery

Completed·—·Phase 3·NCT05624151·75 enrolled

Spinal Anesthesia1 trial

Comparison of Different Doses of Dexmedetomidine Effect in the Duration of Spinal Anesthesia

Unknown status·—·N/A·NCT03143010·200 enrolled

Preoperative Anxiety Experienced by the Pediatric Patient1 trial

Comparison Between the Effects of Adding Intranasal Dexmedetomidine to Two Different Doses of Midazolam as a Premedication in Pediatrics Undergoing Elective Surgery: A Randomized Controlled Trial

Completed·CCairo University·Phase 2·NCT06979791·60 enrolled

Sources

References

[1]
ClinicalTrials.gov — 17 trial records for Dexmedetomidine 5 micrograms. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Dexmedetomidine 5 micrograms compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Dexmedetomidine 5 micrograms. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Udayana University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: UUdayana University

Dexmedetomidine 5 micrograms

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Dexmedetomidine6 trials

Cesarean Section1 trial

Postoperative Pain Relief1 trial

Opioid Free Anesthesia1 trial

Superficial Cervical Plexus Block1 trial

Magnesium Sulfate1 trial

Intracranial Pressure1 trial

Glaucoma1 trial

Quadratus Lumborum Block1 trial

Perioperative Analgesia1 trial

Spinal Anesthesia1 trial

Preoperative Anxiety Experienced by the Pediatric Patient1 trial

References

Drug Info

Quick Facts

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