dextromethorphan hydrobromide

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Breast CancerRheumatoid ArthritisPost Operative Pain

744 competitors in Breast Cancer

#DrugCompanyPhaseTrials

1

Adenocard

Astellas

Preclinical

22

Voltaren

Novartis

Preclinical

13

Zolymbus

AbbVie

Preclinical

14

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

35

Duragesic-100

CCephalon

Preclinical

26

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

27

Spravato

WWim Janssens

Preclinical

28

Tricor

JJagotec

Preclinical

19

Cortef

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

110

Acupan

YYonsei University

Preclinical

1Show 27 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Diabetic Macular Edema1 trial

Dextromethorphan for Diabetic Macular Edema

Completed·NNational Eye Institute (NEI)·Phase 1/2·NCT01441102·7 enrolled

Chronic pain1 trial

Treatment for Chronic Pain in Patients With Advanced Cancer

Completed·NNCIC Clinical Trials Group·Phase 3·NCT00003687·87 enrolled

Major Depressive Disorder1 trial

A Trial of Dextromethorphan for Treatment of Major Depressive Disorder

Completed·MMedical University of South Carolina·Phase 1·NCT02860962·4 enrolled

Drug1 trial

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Completed·Boehringer Ingelheim·Phase 1·NCT02182336·23 enrolled

Homeostasis1 trial

Dextromethorphan, Amantadine and Glucose Homeostasis in Diabetes Subjects

Completed·PProfil Institut für Stoffwechselforschung GmbH·Phase 2·NCT01441986·20 enrolled

10 more indications

Fatigue1 trial

Dextromethorphan in Treating Patients With Fatigue Caused by Cancer

Terminated·UUniversity of Medicine and Dentistry of New Jersey·N/A·NCT00176540·30 enrolled

Metastatic Castration-Resistant Prostate Cancer1 trial

A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer

Completed·Johnson & Johnson·Phase 1·NCT01017939·34 enrolled

Caffeine1 trial

Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers

Completed·Boehringer Ingelheim·Phase 1·NCT02256813·20 enrolled

Post Operative Pain1 trial

Dextromethorphan for Treatment of Postoperative Pain

Recruiting·NNathanael Heckmann·N/A·NCT05278494·160 enrolled

Abortion1 trial

Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion

Completed·SStudy Investigator-Sponsor·Phase 3·NCT03480009·156 enrolled

Patients With Advanced Solid Tumors1 trial

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced Solid Tumors

Completed·NNational Cancer Institute (NCI)·Phase 1·NCT01218620·17 enrolled

Breast Cancer1 trial

Breath Test for Women Receiving Tamoxifen in the Prevention or Treatment of Breast Cancer

Terminated·MMayo Clinic··NCT00873366·92 enrolled

Acute Cough1 trial

Dextromethorphan Pediatric Acute Cough Study

Terminated·Pfizer·Phase 4·NCT02651116·131 enrolled

Rheumatoid Arthritis1 trial

Efficacy Study of Dextromethorphan to Treat Rheumatoid Arthritis

Completed·TTaichung Veterans General Hospital·N/A·NCT02368093·48 enrolled

Unspecified1 trial

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Completed·Boehringer Ingelheim·Phase 1·NCT02243553·34 enrolled

Details

Drug Info

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