Distilled water

PreclinicalSmall molecule

GSK

Distilled water is one of 13 small molecule programs targeting Tinnitus. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

TinnitusActive, not recruiting

TinnitusPreclinical

Active, not recruiting

Competition

Competitive Landscape

14 competitors in Tinnitus

#DrugCompanyPhaseTrials

Levitra

Bayer

Approved

—2

Decadron

AAspen Global Incorporated

Approved

1 3

Paxil

SSebela Pharmaceuticals Development LLC

Xylocaine

Enbrel

1 6

Rayos

RRoxane Laboratories

Preclinical

1 7

Pletal

Otsuka

Preclinical

1 8

IV Lidocaine

WWake Forest University Health Sciences

Phase 1

1 9

Syntocinon

SShana McCormack, MD

Preclinical

1 10

Lidocaine /ml

UUniversity Health Network, Toronto

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

COVID-194 trials

Antiseptic Mouth Rinses to Reduce Salivary Viral Load in COVID-19 Patients

Completed·FFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana·N/A·NCT04707742·160 enrolled

The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load

Completed·KKing Abdulaziz University·Phase 4·NCT04721457·90 enrolled

Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19)

Terminated·UUniversity of California, San Francisco·Phase 2·NCT04409873·54 enrolled

Show 1 more trial

Evaluation of the Efficacy of Mouth Rinses With Commercial Mouthwashes to Decrease Viral Load in Saliva in COVID-19 Patients

Completed·FFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana·N/A·NCT05543603·48 enrolled

Congenital Heart Disease2 trials

Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD)

Completed·SShanghai Jiao Tong University School of Medicine·Phase 3·NCT01598441·8 enrolled

Study of Inhaled Iloprost for the Treatment of Pulmonary Hypertension After Repair of Congenital Heart Disease

Completed·SShanghai Jiao Tong University School of Medicine·Phase 2·NCT01320878·64 enrolled

Pulmonary Hypertension2 trials

Study of Remodulin® in Pediatric Pulmonary Hypertension With Single Ventricular Physiology After Fontan Surgery

Completed·SShanghai Jiao Tong University School of Medicine·Phase 3·NCT02865733·36 enrolled

Study of Inhaled Iloprost in Pediatric Pulmonary Hypertension (PH) After Surgery

Completed·SShanghai Jiao Tong University School of Medicine·Phase 2/3·NCT01310751·36 enrolled

Laryngeal Mask Airway1 trial

Effect of Nebulized Lidocaine on the Quality of Laryngeal Mask Airway Insertion

Unknown status·—·N/A·NCT03361397·80 enrolled

One-lung Ventilation1 trial

The Effect of Iloprost on Oxygenation During One-lung Ventilation for Lung Surgery

Completed·SSeoul St. Mary's Hospital·N/A·NCT03936140·72 enrolled

11 more indications

Silver Diamine Fluoride1 trial

Silver Diamine Fluoride for Caries Prevention in Removable Partial Dentures Wearers

Unknown status·TThe University of Hong Kong·N/A·NCT03185104·196 enrolled

Sore Throat1 trial

Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness of

Completed·TTehran University of Medical Sciences·Phase 3·NCT02114021·99 enrolled

Cesarean Section1 trial

Comparison of Postoperative Analgesic Effect of Intrathecal Clonidine and Fentanyl Added to Bupivacaine in Patients Undergoing Cesarean Section

Completed·QQazvin University Of Medical Sciences·Phase 1/2·NCT01425658·90 enrolled

Anxiety1 trial

Effect of Aromatherapy on Preoperative Anxiety Level

Completed·MMongi Slim Hospital·Phase 4·NCT05853744·90 enrolled

Necrotizing Enterocolitis1 trial

Simulated Amniotic Fluid In Preventing Feeding Intolerance and Necrotizing Enterocolitis VLBW Neonates

Unknown status·RRania Ali El-Farrash·Phase 1·NCT02405637·40 enrolled

Bladder Cancer1 trial

Efficacy of Distilled Water Versus Mitomycin C on Preventing Recurrences of Bladder Cancer After Transurethral Resection

Unknown status·—·Phase 2/3·NCT00816075·40 enrolled

Tinnitus1 trial

Action of Intra-auricular Topical Lidocaine on Tinnitus

Completed·UUniversity of Sao Paulo General Hospital·N/A·NCT05711641·32 enrolled

Irritation1 trial

A Study to Evaluate the Irritation Potential of Tazarotene Foam on Skin in Healthy Volunteers

Completed· GSK logo

GSK·Phase 1·NCT01112787·39 enrolled

Labor Analgesia1 trial

Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial

Unknown status·MMaulana Azad Medical College·Phase 2·NCT02999594·86 enrolled

Dexamethasone1 trial

Dexamethasone and Induction of Delivery

Completed·Ssamar sayed el sayed·Phase 1·NCT03658590·102 enrolled

Cholangitis1 trial

Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis

Recruiting·NNational University of Malaysia·Phase 2·NCT07407491·172 enrolled

Sources

References

[1]
ClinicalTrials.gov — 21 trial records for Distilled water. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Distilled water compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Distilled water. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — GSK company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: GSK

Distilled water

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

COVID-194 trials

Congenital Heart Disease2 trials

Pulmonary Hypertension2 trials

Laryngeal Mask Airway1 trial

One-lung Ventilation1 trial

Silver Diamine Fluoride1 trial

Sore Throat1 trial

Cesarean Section1 trial

Anxiety1 trial

Necrotizing Enterocolitis1 trial

Bladder Cancer1 trial

Tinnitus1 trial

Irritation1 trial

Labor Analgesia1 trial

Dexamethasone1 trial

Cholangitis1 trial

References

Drug Info

Quick Facts

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