Adriamycin

(doxorubicin hydrochloride)

Phase 3Small molecule

Doxorubicin is a chemotherapy drug used to treat various cancers including breast cancer, lymphomas, and leukemias by killing rapidly dividing cancer cells throughout the body.[1] Adriamycin is currently being investigated across 98 indications[3], with its most advanced program in Phase 3.[1]

Adriamycin is one of 1260 small molecule programs targeting AIDS. It is currently in Phase 3.

Indications

552

Total Trials

Active Trials

1,259

Competitors

Pipeline

Status by Indication[3][1]

Indication

AIDSUnknown

Peritoneum CancerActive, not recruiting

HIV InfectionActive, not recruiting

Urinary Bladder CarcinomaUnknown

Non-Hodgkins LymphomaUnknown

Uterine LeiomyosarcomaActive, not recruiting

Primitive Neuroectodermal TumorActive, not recruiting

T-Cell Acute Lymphoblastic LeukemiaActive, not recruiting

Lymphoblastic LymphomaActive, not recruiting

Kidney CancerActive, not recruiting

AIDSPreclinical

Unknown

Peritoneum CancerPhase 3

Active, not recruiting

HIV InfectionPhase 2

Active, not recruiting

Urinary Bladder CarcinomaPreclinical

Unknown

Non-Hodgkins LymphomaPreclinical

Unknown

Uterine LeiomyosarcomaPhase 3

Active, not recruiting

Primitive Neuroectodermal TumorPhase 2

Active, not recruiting

T-Cell Acute Lymphoblastic LeukemiaPhase 2

Active, not recruiting

Lymphoblastic LymphomaPhase 3

Active, not recruiting

Kidney CancerPhase 3

Active, not recruiting

Showing 10 of 98 indications

Competition

Competitive Landscape

2828 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Adriamycin

GGynecologic Oncology Group

Phase 3

87 2

Tecentriq

Roche

Preclinical

36 3

Trodelvy

Gilead

Preclinical

37 4

Gemzar

GGynecologic Oncology Group

Preclinical

22 5

Lupron

EEastern Cooperative Oncology Group

Preclinical

5 6

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

3 7

Zinecard

CChildren's Oncology Group

Preclinical

2 8

Apatinib Mesylate

BBukwang Pharmaceutical

Preclinical

3 9

Motexafin Gadolinium

PPharmacyclics LLC.

Preclinical

1 10

Dextromethorphan Hydrobromide

Boehringer Ingelheim

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Phase 2Active, not recruiting

Breast Cancer

NCT00295893

Phase 1Active, not recruiting

Lymphoma

NCT02337985

Phase 3Active, not recruiting

T-Cell Acute Lymphoblastic Leukemia

NCT02112916

Q4 2026

Phase 2Active, not recruiting

Lymphoma

NCT03749018

Q4 2027

Phase 2Active, not recruiting

Classic Hodgkin Lymphoma

NCT05922904

Q1 2028

Phase 3Active, not recruiting

Acute Lymphoblastic Leukemia

NCT01190930

Clinical

Trials by Indication[1]

Breast Cancer36 trials

Combination Chemotherapy With or Without Darbepoetin Alfa in Treating Women With Stage III Breast Cancer

Unknown status·HHeinrich-Heine University, Duesseldorf·N/A·NCT00309920·1,234 enrolled

Combination Chemotherapy and Trastuzumab in Treating Women With Stage I, Stage II, or Stage III HER2-Positive Breast Cancer

Unknown status·AAzienda Ospedaliero-Universitaria di Modena·Phase 3·NCT00629278·2,500 enrolled

Chemotherapy Combined With Gene Therapy in Treating Patients Who Have Stage III or Stage IV Breast Cancer

Completed·IIntrogen Therapeutics·Phase 2·NCT00044993

Show 33 more trials

Doxorubicin Hydrochloride, Cyclophosphamide, Docetaxel, and S-1 Before Surgery in Treating Women With Stage II or Stage III Breast Cancer

Unknown status·YYonsei University·Phase 2·NCT00994968·49 enrolled

Chemotherapy Followed by Surgery in Treating Women With Stage II or Stage III Breast Cancer

Completed·—·Phase 2·NCT00003953·39 enrolled

Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer

Completed·—·Phase 2·NCT00003042·41 enrolled

Paclitaxel, Doxorubicin, and Cyclophosphamide With Or Without Carboplatin in Treating Women With Locally Advanced Breast Cancer That Can Be Removed by Surgery

Terminated·NNational Cancer Centre, Singapore·Phase 2·NCT00589238·16 enrolled

Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer

Terminated·—·N/A·NCT01897441·31 enrolled

Doxorubicin and Cyclophosphamide Followed by Paclitaxel, Trastuzumab, and Lapatinib in Treating Patients With HER2/Neu-Overexpressed Breast Cancer

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00482391·95 enrolled

Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery

Completed·UUniversity of Washington·Phase 2·NCT00194779·50 enrolled

Sunitinib Malate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide Before Surgery in Treating Patients With Stage IIB-IIIC Breast Cancer

Completed·UUniversity of Washington·Phase 2·NCT00513695·68 enrolled

Cyclophosphamide and Docetaxel or Doxorubicin in Treating Women With Newly Diagnosed Breast Cancer That Can Be Removed by Surgery

Unknown status·NNational Cancer Centre, Singapore·Phase 2·NCT00801411·318 enrolled

Studying Tissue Samples From Women Who Underwent Chemotherapy for Lymph Node-Positive Stage II or Stage IIIA Breast Cancer on Clinical Trial CLB-9741 or CLB-9344

Completed·AAlliance for Clinical Trials in Oncology··NCT00897026·1,195 enrolled

Combination Chemotherapy With or Without Trastuzumab in Treating Patients With Stage II or Stage III Breast Cancer

Active, not recruiting·—·Phase 2·NCT00295893·121 enrolled

S9623, Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer

Terminated·SSWOG Cancer Research Network·Phase 3·NCT00002772·602 enrolled

Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer

Completed·NNational Cancer Institute (NCI)·Phase 3·NCT01275677·3,270 enrolled

Combination Chemotherapy With or Without Microwave Thermotherapy Before Surgery in Treating Women With Locally Advanced Breast Cancer

Unknown status·IImunon·Phase 2·NCT00036985

Comparison of Three Combination Chemotherapy Regimens in Treating Women With Stage I or Stage II Breast Cancer

Completed·RRoyal Marsden NHS Foundation Trust·Phase 2·NCT00004237

Bevacizumab, Doxorubicin, and Cyclophosphamide Followed By Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab in Treating Patients Who Have Undergone Surgery for Early-Stage Breast Cancer

Unknown status·MMemorial Sloan Kettering Cancer Center·N/A·NCT00436709·75 enrolled

PTX-200, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancer

Terminated·PPrescient Therapeutics, Ltd.·Phase 1/2·NCT01697293·34 enrolled

Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women)

Completed·UUniversity of Nebraska·Phase 2·NCT00499083·17 enrolled

SU5416 and Doxorubicin in Treating Patients With Stage IIIB or Stage IV Inflammatory Breast Cancer

Completed·—·Phase 1·NCT00005822·21 enrolled

Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer

Completed·SScottish Cancer Therapy Network·Phase 3·NCT00002755·600 enrolled

Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer

Active, not recruiting·NNational Cancer Institute (NCI)·Phase 3·NCT00433511·4,994 enrolled

Combination Chemotherapy in Treating Women With Stage II or Stage IIIA Breast Cancer That Has Spread to the Lymph Nodes

Completed·EEastern Cooperative Oncology Group·Phase 3·NCT00004125

Doxorubicin or Epirubicin and Cyclophosphamide in Treating Older Women With Invasive Breast Cancer

Unknown status·—·Phase 3·NCT00516425·1,000 enrolled

High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Combination Chemotherapy in Treating Women With High-Risk Breast Cancer

Completed·EETOP IBCSG Partners Foundation·Phase 3·NCT00002784·344 enrolled

Targeted T Cells After Neoadjuvant Chemotherapy in Treating Women With Stage II or III Breast Cancer Undergoing Surgery

Terminated·BBarbara Ann Karmanos Cancer Institute·Phase 2·NCT01147016·8 enrolled

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Stage II or Stage III Breast Cancer

Withdrawn·RRoger Williams Medical Center·Phase 1/2·NCT00022230

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

Completed·UUniversity of California, San Francisco··NCT00755313·81 enrolled

Combination Chemotherapy in Treating Patients With High-Risk Breast Cancer

Completed·—·Phase 2·NCT00004092·72 enrolled

Combination Chemotherapy in Treating Women With Breast Cancer

Unknown status·SScottish Cancer Therapy Network·Phase 3·NCT00003679·350 enrolled

Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

Completed·MMayo Clinic·Phase 2·NCT00436566·122 enrolled

Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer

Completed·IInstitute of Cancer Research, United Kingdom·Phase 3·NCT00002582·6,000 enrolled

Allogeneic Transplantation Using Mini-Conditioning for Treatment of Stage IV Breast Cancer

Withdrawn·—·Phase 2·NCT00006261

Tamoxifen in Treating Women With High-Risk Breast Cancer

Completed·NNCIC Clinical Trials Group·Phase 3·NCT00002542·672 enrolled

Lymphoma35 trials

Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma

Completed·CChildren's Oncology Group·Phase 3·NCT01026220·166 enrolled

Nivolumab With DA-REPOCH Chemotherapy Regimen in Treating Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

Active, not recruiting·—·Phase 2·NCT03749018·30 enrolled

Combination Chemotherapy Plus Rituximab in Treating Patients With Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma

Unknown status· Amgen logo

Amgen·Phase 2·NCT00005959

Show 32 more trials

S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma

Completed·SSWOG Cancer Research Network·Phase 2·NCT00822120·371 enrolled

Combination Chemotherapy Plus Filgrastim With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma

Unknown status·CCommissie Voor Klinisch Toegepast Onderzoek·Phase 3·NCT00028717·400 enrolled

S0014 Combination Chemotherapy Plus Rituximab and Radiation Therapy in Treating Patients With Stage I or Stage II Non-Hodgkin's Lymphoma

Completed·SSWOG Cancer Research Network·Phase 2·NCT00005089·71 enrolled

Gene Therapy and Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma

Active, not recruiting·—·Phase 1·NCT02337985·10 enrolled

Combination Chemotherapy in Treating Older Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma

Completed·CCancer Research Campaign Clinical Trials Centre·Phase 3·NCT00002576·200 enrolled

Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Lymphoma

Completed·CChildren's Oncology Group·Phase 3·NCT00302003·287 enrolled

Positron Emission Tomography Using Fludeoxyglucose F 18 in Predicting Response to Treatment in Patients Who Are Receiving Rituximab and Combination Chemotherapy for Newly Diagnosed Non-Hodgkin's Lymphoma

Withdrawn·—·N/A·NCT00110006

High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma

Unknown status·CCancer Research UK·Phase 2·NCT00669812·60 enrolled

S0349 Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone With or Without Oblimersen in Treating Patients With Advanced Diffuse Large B-Cell Non-Hodgkin's Lymphoma

Terminated·NNational Cancer Institute (NCI)·Phase 2·NCT00080847·160 enrolled

Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas

Completed·NNational Cancer Institute (NCI)·Phase 1/2·NCT01193842·107 enrolled

Combination Chemotherapy, Rituximab, and Ixazomib Citrate in Treating Patients With Non-Hodgkin Lymphoma

Unknown status·NNorthwestern University·Phase 1/2·NCT02481310·38 enrolled

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma

Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00049595·552 enrolled

A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 3·NCT00000658·250 enrolled

Rituximab and Combination Chemotherapy With or Without Bleomycin Sulfate in Treating Patients With Primary Mediastinal Large B-Cell Lymphoma

Withdrawn·OOhio State University Comprehensive Cancer Center·Phase 2·NCT00983944

Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma

Completed·NNorthwestern University·Phase 1·NCT03742258·12 enrolled

PET-Directed Therapy With Pembrolizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Classical Hodgkin Lymphoma

Unknown status·NNorthwestern University·Phase 2·NCT03226249·30 enrolled

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Aggressive Non-Hodgkin's Lymphoma

Completed·SSwiss Cancer Institute·Phase 3·NCT00003215·400 enrolled

Combination Chemotherapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma

Completed·LLymphoma Trials Office·Phase 3·NCT00005867·310 enrolled

Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma

Unknown status·CChildren's Cancer and Leukaemia Group·Phase 2·NCT00025064·260 enrolled

Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma

Completed·UUniversity College, London·Phase 3·NCT00678327·1,202 enrolled

Rituximab and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Non-Hodgkin's Lymphoma

Completed·EEastern Cooperative Oncology Group·Phase 2·NCT00274924·100 enrolled

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Recruiting·AAIDS Malignancy Consortium·Phase 1·NCT04139304·15 enrolled

Rituximab Followed by Combination Chemotherapy in Treating Patients With Refractory or Recurrent Non-Hodgkin's Lymphoma

Withdrawn·MMedstar Health Research Institute·Phase 2·NCT00006669

S9911, Combination Chemotherapy Plus Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma

Completed·SSWOG Cancer Research Network·Phase 2·NCT00003784·102 enrolled

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Previously Untreated Aggressive Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma

Completed·AAlliance for Clinical Trials in Oncology·Phase 2·NCT00005964·59 enrolled

Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma

Completed·AAlliance for Clinical Trials in Oncology·Phase 2·NCT00032019·78 enrolled

Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma

Completed·UUniversity of Nebraska·Phase 1/2·NCT02561273·54 enrolled

GM-CSF, Rituximab, and Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Follicular Non-Hodgkin Lymphoma

Unknown status·FFrench Innovative Leukemia Organisation·Phase 2·NCT00896519·30 enrolled

Vaccine Therapy Plus Sargramostim Following Chemotherapy in Previously Untreated Aggressive Non-Hodgkin's Lymphoma

Completed·UUniversity of Nebraska·Phase 2·NCT00004197

Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000703·45 enrolled

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Previously Untreated HIV-Associated Non-Hodgkin's Lymphoma

Completed·NNational Cancer Institute (NCI)·Phase 3·NCT00003595·120 enrolled

Doxorubicin Hydrochloride, Pembrolizumab, Vinblastine, and Dacarbazine in Treating Patients With Classical Hodgkin Lymphoma

Completed·UUniversity of Washington·Phase 1/2·NCT03331341·50 enrolled

Acute Lymphoblastic Leukemia13 trials

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Active, not recruiting·CChildren's Oncology Group·Phase 3·NCT01190930·9,350 enrolled

Carfilzomib and Hyper-CVAD in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoma

Completed·MMehrdad Abedi, MD·Phase 1·NCT02293109·10 enrolled

Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Completed·CChildren's Oncology Group·Phase 3·NCT00671034·166 enrolled

Show 10 more trials

Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Withdrawn·UUniversity of Washington·Phase 2·NCT02538926

International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia

Completed·UUniversity Hospital Schleswig-Holstein·Phase 3·NCT01117441·6,136 enrolled

Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Unknown status·OOhio State University Comprehensive Cancer Center·Phase 2·NCT01005758·180 enrolled

Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma

Completed·CChildren's Oncology Group·Phase 3·NCT01230983·573 enrolled

Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

Unknown status·UUniversitätsklinikum Hamburg-Eppendorf·N/A·NCT00343369·550 enrolled

Pegaspargase and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Terminated·OOHSU Knight Cancer Institute·Phase 2·NCT01005914·11 enrolled

Dose Adjusted EPOCH Regimen in Combination With Ofatumumab or Rituximab in Treating Patients With Newly Diagnosed or Relapsed or Refractory Burkitt Lymphoma or Relapsed or Refractory Acute Lymphoblastic Leukemia

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT02199184·14 enrolled

Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia

Unknown status·MMedical Research Council·Phase 3·NCT00003437·1,800 enrolled

Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia

Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00002700·392 enrolled

Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia

Completed·OOHSU Knight Cancer Institute·Phase 1·NCT02779283·7 enrolled

Soft Tissue Sarcoma13 trials

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma

Completed·CChildren's Oncology Group·Phase 2·NCT00002804·43 enrolled

Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone Sarcoma

Terminated·—·Phase 2·NCT00544778·7 enrolled

Doxorubicin Plus External-Beam Radiation Therapy in Treating Patients With Soft Tissue Sarcoma

Completed·MM.D. Anderson Cancer Center·Phase 1·NCT00004109·30 enrolled

Show 10 more trials

Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma

Completed·CChildren's Oncology Group·Phase 3·NCT00346164·588 enrolled

PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma

Completed·MMasonic Cancer Center, University of Minnesota·N/A·NCT00346125·70 enrolled

Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma

Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00061984·455 enrolled

Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma

Completed·NNational Cancer Institute (NCI)·Phase 1·NCT00720174·30 enrolled

Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma

Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00003212·780 enrolled

Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma

Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00003052·340 enrolled

SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma

Recruiting·MM.D. Anderson Cancer Center·Phase 2·NCT07049848·50 enrolled

Combination Chemotherapy in Treating Patients With Soft Tissue Sarcoma

Completed·UUniversity of Miami·Phase 2·NCT00002492

A Phase 2 Clinical Study of Evaluation of Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection (609A) Combined With Doxorubicin Hydrochloride in the Treatment of Metastatic/Unresectable Non-specific Soft Tissue Sarcoma

Unknown status·SSunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.·Phase 2·NCT05138146·70 enrolled

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Completed·OOHSU Knight Cancer Institute·Phase 1·NCT03009201·16 enrolled

Mantle Cell Lymphoma7 trials

Combination Chemotherapy With or Without Bortezomib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Completed·UUniversity Hospital Plymouth NHS Trust·Phase 2·NCT00513955·50 enrolled

Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT00003311·19 enrolled

Combination Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma

Completed·MMemorial Sloan Kettering Cancer Center·Phase 1/2·NCT00003541·24 enrolled

Show 4 more trials

Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Completed·RRoswell Park Cancer Institute·Phase 2·NCT01527149·37 enrolled

Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma

Recruiting·—·Phase 2·NCT04626791·45 enrolled

Combination Chemotherapy, Bone Marrow or Peripheral Stem Cell Transplantation, and/or Biological Therapy in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma

Completed·NNorthwestern University·Phase 2·NCT00004231

S0601 Rituximab, Combination Chemotherapy, and Bortezomib Followed by Bortezomib Alone in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Completed·SSWOG Cancer Research Network·Phase 2·NCT00376961·68 enrolled

48 more indications

Hodgkin's Disease6 trials

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Completed·CChildren's Oncology Group·Phase 3·NCT00005578·219 enrolled

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Early-Stage Hodgkin's Disease

Completed·SStanford University·Phase 2·NCT00002714

Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease

Completed·MMedical Research Council·Phase 3·NCT00003421·800 enrolled

Show 3 more trials

Phase II Study of Filgrastim (G-CSF) Plus ABVD in the Treatment of HIV-Associated Hodgkin's Disease

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00000626·27 enrolled

Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease

Completed·CChildren's Oncology Group·Phase 3·NCT00025259·1,734 enrolled

Radiation Therapy and Chemotherapy in Treating Patients With Hodgkin's Disease

Completed·NNCIC Clinical Trials Group·Phase 3·NCT00002561·405 enrolled

Neuroblastoma6 trials

Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma

Completed·—·Phase 3·NCT00002802·500 enrolled

Topotecan, Vincristine, and Doxorubicin in Treating Young Patients With Refractory Stage 4 Neuroblastoma

Unknown status·CChildren's Cancer and Leukaemia Group·Phase 2·NCT00392340·63 enrolled

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma

Completed·CChildren's Oncology Group·Phase 1·NCT00002740·30 enrolled

Show 3 more trials

Surgery in Treating Children With Neuroblastoma

Completed·CChildren's Oncology Group·Phase 3·NCT00003119·968 enrolled

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma

Completed·CChildren's Oncology Group·Phase 3·NCT00004188·495 enrolled

Combination Chemotherapy or Observation Following Surgery in Treating Infants With Neuroblastoma

Completed·—·Phase 2·NCT00002803·44 enrolled

Prostate Cancer6 trials

Combination Chemotherapy Plus Warfarin in Treating Patients With Prostate Cancer

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00014352

Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer

Completed·MM.D. Anderson Cancer Center·Phase 3·NCT00002855·306 enrolled

Combination Chemotherapy With Ketoconazole in Treating Patients With Prostate Cancer

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT00003084·75 enrolled

Show 3 more trials

Combination Chemotherapy in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy

Unknown status· Amgen logo

Amgen·Phase 2·NCT00005960

Hormone Therapy Plus Chemotherapy in Treating Patients With Prostate Cancer

Completed· Radiation Therapy Oncology Group logo

Radiation Therapy Oncology Group·Phase 3·NCT00030654·21 enrolled

Doxorubicin and Strontium-89 With or Without Celecoxib in Treating Patients With Progressive Androgen-Independent Prostate Cancer and Bone Metastases

Terminated·MM.D. Anderson Cancer Center·Phase 2·NCT00080782·14 enrolled

Multiple Myeloma5 trials

Combination Chemotherapy With or Without Thalidomide in Treating Patients With Multiple Myeloma

Unknown status·CCommissie Voor Klinisch Toegepast Onderzoek·Phase 3·NCT00028886·450 enrolled

S0833, Bortezomib, Thalidomide, Lenalidomide, Combination Chemotherapy, and Autologous Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma

Withdrawn·SSWOG Cancer Research Network·Phase 2·NCT01055301

Combination Chemotherapy With or Without Cyclophosphamide and Prednisone in Treating Older Patients With Multiple Myeloma

Unknown status·MMedical Research Council·Phase 3·NCT00002653·1,000 enrolled

Show 2 more trials

Thalidomide, Doxorubicin, and Dexamethasone in Treating Patients With Untreated Stage II or Stage III Multiple Myeloma

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00008242

Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple Myeloma

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT00006184·20 enrolled

Liver Cancer5 trials

Sorafenib Tosylate and Chemoembolization in Treating Patients With Unresectable Liver Cancer

Completed·—·Phase 1·NCT01042041·18 enrolled

Doxorubicin and Interleukin-2 in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Completed·RRoswell Park Cancer Institute·Phase 2·NCT00004248·24 enrolled

Thalidomide and Chemoembolization With Doxorubicin in Treating Patients With Liver Cancer That Cannot be Removed by Surgery

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT00006016·75 enrolled

Show 2 more trials

Sunitinib and Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Terminated·RRoswell Park Cancer Institute·Phase 2·NCT00524316·16 enrolled

Combination Chemotherapy and Interferon Alfa-2b in Treating Patients With Nonmetastatic Liver Cancer That Cannot Be Removed by Surgery

Unknown status·NNational Cancer Centre, Singapore·Phase 2·NCT00471484·54 enrolled

Endometrial Cancer5 trials

Combination Chemotherapy With or Without G-CSF in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Completed·GGynecologic Oncology Group·Phase 3·NCT00003691·240 enrolled

Intraperitoneal Paclitaxel, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Stage III-IV Endometrial Cancer

Completed·GGynecologic Oncology Group·Phase 1·NCT00575952·27 enrolled

Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Advanced Endometrial Cancer

Completed·GGynecologic Oncology Group·Phase 3·NCT00002493

Show 2 more trials

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Endometrial Cancer

Completed·NNordic Society of Gynaecological Oncology - Clinical Trials Unit·Phase 3·NCT00005583·400 enrolled

Doxorubicin, Paclitaxel, and Carboplatin in Treating Patients With Primary Stage III, Stage IV, or Recurrent Endometrial Cancer

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00006377

Diffuse Large B-Cell Lymphoma4 trials

Oblimersen Sodium & Combination Chemotherapy in Treating Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma

Terminated·UUniversity of Nebraska·Phase 1·NCT00736450·37 enrolled

Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Lymphoma

Completed·—·Phase 1/2·NCT02073097·48 enrolled

Nivolumab and Combination Chemotherapy in Treating Participants With Diffuse Large B-Cell Lymphoma

Suspended·NNorthwestern University·Phase 1/2·NCT03704714·30 enrolled

Show 1 more trial

Combination Chemo, Rituximab, and Bevacizumab in Older Patients With Stage II-IV Diffuse Large B-Cell Lymphoma

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT00121199·73 enrolled

Advanced Cancer3 trials

Two-Drug Combination Chemotherapy Compared With Four-Drug Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium

Completed·EEastern Cooperative Oncology Group·Phase 3·NCT00003376·330 enrolled

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

Completed·UUniversity of Wisconsin, Madison·Phase 1·NCT00036790

Combination Chemotherapy in Treating Patients With Recurrent or Advanced Cancer of the Uterus

Terminated·GGynecologic Oncology Group·Phase 2·NCT00002993·30 enrolled

Bone Marrow Transplantation3 trials

Chemotherapy, Radiation Therapy, Immunotherapy, and Bone Marrow Transplantation in Treating Patients With Neuroblastoma

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00002634·45 enrolled

High Dose Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma

Unknown status·LLymphoma Trials Office·Phase 3·NCT00003578·500 enrolled

Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma

Completed·SSt. Jude Children's Research Hospital·Phase 2·NCT00004006·4 enrolled

Stem Cell Transplantation3 trials

Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma

Unknown status·MMedical Research Council·Phase 3·NCT00002599·750 enrolled

S9901 Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Men With Stage III or Stage IV Hodgkin's Disease

Terminated·SSWOG Cancer Research Network·Phase 3·NCT00005090·11 enrolled

Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors

Completed·CChildren's Oncology Group·Phase 3·NCT00002610·203 enrolled

Bladder Cancer3 trials

Combination Chemotherapy in Treating Patients With Bladder Cancer

Completed·AAlliance for Clinical Trials in Oncology·Phase 3·NCT00014534·42 enrolled

Combination Chemotherapy in Treating Patients With Stage II Bladder Cancer

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00002919·30 enrolled

Transurethral Resection and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer

Terminated·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 2·NCT00003640·73 enrolled

Rhabdomyosarcoma3 trials

Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors

Completed·SSociete Internationale d'Oncologie Pediatrique·Phase 2·NCT00025441

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT01055314·175 enrolled

High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or Ectomesenchymoma

Completed·CChildren's Oncology Group·Phase 3·NCT00354744·109 enrolled

Kidney Cancer2 trials

Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer

Completed·CChildren's Oncology Group·Phase 3·NCT00002611·3,031 enrolled

Combination Chemotherapy in Treating Patients With Advanced Bladder or Kidney Cancer

Completed·MMemorial Sloan Kettering Cancer Center·Phase 1·NCT00003342·30 enrolled

Ewing sarcoma2 trials

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Completed·CChildren's Oncology Group·N/A·NCT00618813·35 enrolled

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma

Completed·CChildren's Oncology Group·Phase 3·NCT01231906·642 enrolled

Kaposi's sarcoma2 trials

A Study of Doxorubicin in the Treatment of AIDS-Related Kaposi's Sarcoma

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00000996·48 enrolled

A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcoma

Unknown status·SSequus Pharmaceuticals·Phase 3·NCT00002318·225 enrolled

Anaplastic Large Cell Lymphoma2 trials

Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Completed·CChildren's Oncology Group·Phase 1·NCT01606878·46 enrolled

Combination Chemotherapy in Treating Children With Anaplastic Large Cell Lymphoma (ALCL 99)

Completed·GGustave Roussy, Cancer Campus, Grand Paris·Phase 3·NCT00006455·885 enrolled

Osteosarcoma2 trials

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT00023998·80 enrolled

Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

Completed·CChildren's Oncology Group·Phase 1·NCT00742924·24 enrolled

Radiation Therapy2 trials

Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma

Unknown status·UUniversity Hospital Muenster·Phase 3·NCT00002516

Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor

Active, not recruiting·CChildren's Oncology Group·Phase 3·NCT00352534·808 enrolled

Induction Therapy2 trials

Cladribine and Rituximab as Remission Induction Therapy Followed By Rituximab and Stem Cell Mobilization in Treating Patients With CLL

Completed·SSwiss Cancer Institute·Phase 2·NCT00072007·43 enrolled

Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak)

Terminated·UUniversity of California, San Francisco·Phase 2·NCT00632827·21 enrolled

Leukemia2 trials

Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma

Completed·MMemorial Sloan Kettering Cancer Center·Phase 3·NCT00002766·170 enrolled

High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia

Completed·WWake Forest University Health Sciences·Phase 2·NCT00002865·25 enrolled

Patients With Solid Tumors1 trial

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Completed·OOttawa Regional Cancer Centre·Phase 2·NCT00002608·30 enrolled

Classic Hodgkin Lymphoma1 trial

PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma

Active, not recruiting·MM.D. Anderson Cancer Center·Phase 2·NCT05922904·25 enrolled

Ewing's Sarcoma1 trial

Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors

Completed·CChildren's Oncology Group·Phase 2·NCT00061893·38 enrolled

Nausea and vomiting1 trial

Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer

Completed·UUniversity of Washington·N/A·NCT00343863·41 enrolled

T-cell acute lymphoblastic leukemia1 trial

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active, not recruiting·NNational Cancer Institute (NCI)·Phase 3·NCT02112916·847 enrolled

Wilms tumor1 trial

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor

Active, not recruiting·CChildren's Oncology Group·Phase 3·NCT00945009·249 enrolled

Chemotherapy1 trial

Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor

Completed·CChildren's Oncology Group·Phase 3·NCT00304070·78 enrolled

Lung Cancer1 trial

Inhaled Doxorubicin in Treating Patients With Primary Lung Cancer or Lung Metastases

Completed·MMemorial Sloan Kettering Cancer Center·Phase 1·NCT00004930

Ovarian Epithelial Cancer1 trial

Adjuvant Chemotherapy Compared With Observation in Treating Patients With Resected Early Stage Ovarian Epithelial Cancer

Unknown status·MMedical Research Council·Phase 3·NCT00002477

Metastatic Cancer1 trial

Combination Chemotherapy in Treating Patients With Metastatic Cancer of an Unknown Site of Origin

Unknown status·TThe Christie NHS Foundation Trust·Phase 3·NCT00022178

Primitive Neuroectodermal Tumor1 trial

Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT00002643·130 enrolled

Chronic Lymphocytic Leukemia1 trial

Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia

Completed·LLeukemia Research Fund·Phase 3·NCT00004218

Richter Transformation1 trial

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

Not yet recruiting·SSWOG Cancer Research Network·Phase 3·NCT07220187·102 enrolled

Immunosuppression1 trial

SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant

Completed·SSWOG Cancer Research Network·Phase 2·NCT00002657·20 enrolled

Small Cell Lung Cancer1 trial

Radiation Therapy Plus Combination Chemotherapy In Treating Patients With Limited Stage Small Cell Lung Cancer

Completed·LLondon Lung Cancer Group·Phase 3·NCT00003364·398 enrolled

Recurrent Sarcoma1 trial

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Recruiting·MM.D. Anderson Cancer Center·N/A·NCT04199026·20 enrolled

B-cell acute lymphoblastic leukemia1 trial

Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia

Completed·CChildren's Oncology Group·Phase 3·NCT00381680·275 enrolled

Lymphoblastic Lymphoma1 trial

Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma

Completed·CChildren's Oncology Group·Phase 3·NCT00004228·393 enrolled

Thyroid Cancer1 trial

Induction Chemotherapy Using Doxorubicin and Cisplatin Followed by Combretastatin A4 Phosphate and Radiation Therapy in Treating Patients With Newly Diagnosed Regionally Advanced Anaplastic Thyroid Cancer

Terminated·—·Phase 1/2·NCT00077103·4 enrolled

Neuroectodermal Tumors1 trial

Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00002466

Ovarian Carcinoma1 trial

Phase II Clinical Study of Pegylated Liposomal Doxorubicin Hydrochloride Injection as 2nd-line or Later Therapy in Patients With Mullerian Carcinoma (Epithelial Ovarian Carcinoma, Primary Carcinoma of Fallopian Tube, Peritoneal Carcinoma) Having Prior Platinum-Based Chemotherapy

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 2·NCT00216645·74 enrolled

Mycosis Fungoides1 trial

Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides

Unknown status·NNational Cancer Institute (NCI)·Phase 2·NCT00002557·3 enrolled

Pembrolizumab1 trial

Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by Surgery

Completed·FFred Hutchinson Cancer Center·Phase 1/2·NCT02888665·37 enrolled

Terminated·UUNICANCER·Phase 3·NCT00003682·160 enrolled

HIV infection1 trial

Combination Chemotherapy in Treating Patients With Hodgkin's Disease and HIV Infection

Unknown status·CCentro di Riferimento Oncologico - Aviano·Phase 2·NCT00003262·30 enrolled

Hepatocellular Carcinoma1 trial

Doxorubicin By Infusion or Chemoembolization in Treating Patients With Advanced Unresectable Hepatocellular Carcinoma (Liver Cancer)

Unknown status·UUniversity Hospital Birmingham·Phase 3·NCT00079027·280 enrolled

Sources

References

[1]
ClinicalTrials.gov — 552 trial records for doxorubicin hydrochloride. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — doxorubicin hydrochloride compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for doxorubicin hydrochloride. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Gynecologic Oncology Group company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: DNA Topoisomerase II Alpha Inhibitor[2]
Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: GGynecologic Oncology Group

Adriamycin

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2026

Q4 2026

Q4 2027

Q1 2028

Trials by Indication[1]

Breast Cancer36 trials

Lymphoma35 trials

Acute Lymphoblastic Leukemia13 trials

Soft Tissue Sarcoma13 trials

Mantle Cell Lymphoma7 trials

Hodgkin's Disease6 trials

Neuroblastoma6 trials

Prostate Cancer6 trials

Multiple Myeloma5 trials

Liver Cancer5 trials

Endometrial Cancer5 trials

Diffuse Large B-Cell Lymphoma4 trials

Advanced Cancer3 trials

Bone Marrow Transplantation3 trials

Stem Cell Transplantation3 trials

Bladder Cancer3 trials

Rhabdomyosarcoma3 trials

Kidney Cancer2 trials

Ewing sarcoma2 trials

Kaposi's sarcoma2 trials

Anaplastic Large Cell Lymphoma2 trials

Osteosarcoma2 trials

Radiation Therapy2 trials

Induction Therapy2 trials

Leukemia2 trials

Patients With Solid Tumors1 trial

Classic Hodgkin Lymphoma1 trial

Ewing's Sarcoma1 trial

Nausea and vomiting1 trial

T-cell acute lymphoblastic leukemia1 trial

Wilms tumor1 trial

Chemotherapy1 trial

Lung Cancer1 trial

Ovarian Epithelial Cancer1 trial

Metastatic Cancer1 trial

Primitive Neuroectodermal Tumor1 trial

Chronic Lymphocytic Leukemia1 trial

Richter Transformation1 trial

Immunosuppression1 trial

Small Cell Lung Cancer1 trial

Recurrent Sarcoma1 trial

B-cell acute lymphoblastic leukemia1 trial

Lymphoblastic Lymphoma1 trial

Thyroid Cancer1 trial

Neuroectodermal Tumors1 trial

Ovarian Carcinoma1 trial

Mycosis Fungoides1 trial

Pembrolizumab1 trial

Malignant Peripheral Nerve Sheath Tumor1 trial

Central Nervous System Lymphoma1 trial

Metastatic Prostate Cancer1 trial

HIV infection1 trial

Hepatocellular Carcinoma1 trial

References

Drug Info

Quick Facts

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