Hepatitis B vaccine

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

MemoryHepatitis BCeliac DiseaseVaccinationChronic Hepatitis B

48 competitors in Memory

#DrugCompanyPhaseTrials

1

Aricept

Eisai

Approved

72

Myrbetriq

Astellas

Approved

13

Ritalin

Novartis

Approved

14

Inderal

WWyeth-Lederle Vaccines

Approved

65

Ambien

PPurdue Pharma LP

Approved

36

Intuniv

PPromius Pharma, LLC

Approved

27

Pitocin

RRetrophin

Approved

18

Mifeprex

DDanco

Approved

19

Rilutek

AAzurity Pharmaceuticals

Approved

110

Nuvigil

NNuvo Research GmbH

Approved

1Show 30 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Hepatitis B20 trials

Strategies for the Prevention of Hepatitis B Among HIV Infected Patients in Uganda

Completed·FFred Hutchinson Cancer Center·Phase 4·NCT02316444·132 enrolled

New Methods to Measure the Immune Response to Hepatitis B Vaccine

Completed·UUniversity of Oxford·Phase 4·NCT01821547·21 enrolled

Dose of Hepatitis B Vaccines in Non/Low-response Populations

Completed·WWu Jiang·N/A·NCT01564134·537 enrolled

Show 17 more trials

Optimal Timing of Hepatitis B Vaccination After Transplants

Not yet recruiting·IInstitute of Hematology & Blood Diseases Hospital, China·Phase 3·NCT06888479·1,500 enrolled

Immunity to Hepatitis B Vaccine

Completed·UUniversity of British Columbia·Phase 4·NCT03083158·16 enrolled

Persistence of the Immune Response to Hepatitis B in 4-6 Years Old Children Previously Vaccinated With DTPa-HBV-IPV/Hib

Completed·GSK·Phase 4·NCT00335881·300 enrolled

VaxTeen Hepatitis B Vaccine Booster Study

Completed·CCenters for Disease Control and Prevention·Phase 4·NCT00144313·60 enrolled

Persistence of the Immune Response to Hepatitis B in 7-9 Years Old Children Previously Vaccinated With DTPa-HBV-IPV/Hib

Completed·GSK·Phase 4·NCT00356564·350 enrolled

Immunogenicity of Influenza, Pneumococcal and Hepatitis B Vaccines in IBD Patients Treated With Vedolizumab

Completed·—··NCT03056924·173 enrolled

A Trial Investigating the Influence of BCG and Hepatitis B Immunisation at Birth on Neonatal Immune Responses: The Early Life Vaccines and Immunity Study

Completed·MMurdoch Childrens Research Institute·N/A·NCT02444611·185 enrolled

A Study of 2 Doses of a Hepatitis B Vaccine (V232 RECOMBIVAX HB) in Healthy Infants (V232-057)

Completed·Merck & Co.·Phase 3·NCT00414050·1,718 enrolled

Efficacy of Hepatitis B Vaccine Boosters Among Neonatally Vaccinated Children in Chongqing

Unknown status·—··NCT03867643·80 enrolled

Hepatitis B Virus Antibody Booster Program for the Production of Hepatitis B Immune Globulin (HBIG)

Terminated·Emergent BioSolutions·Phase 3·NCT01311674·141 enrolled

The Hepatitis B Vaccine Booster Response Among the Youth Who Had Completed Neonatal Hepatitis B Vaccines

Completed·NNational Taiwan University Hospital·N/A·NCT00792610·127 enrolled

A Randomized,Parallel-group Clinical Trial of Hepatitis B Vaccine With Different Dosages and Schedules in Healthy Adults

Completed·PPeking University·Phase 4·NCT02203357·353 enrolled

Comparison of Monodose and Multidose Presentations of GSK Biologicals' Hepatitis B Vaccine in Terms of Immune Response

Completed·GSK·Phase 4·NCT00197158·280 enrolled

The Effect of Alendronate on the Immune Response to Hepatitis B Vaccine in Healthy Adults

Completed·MMassachusetts General Hospital·Phase 1·NCT02057263·28 enrolled

Response to Booster Doses of Hepatitis B Vaccine in Children and Adolescents

Completed·CCenters for Disease Control and Prevention··NCT00141999·400 enrolled

Immunologic Response of Hepatitis B Vaccine

Unknown status·—·Phase 4·NCT03219203·80 enrolled

Adolescents' Response to Hepatitis B Vaccine Booster Dose

Unknown status·—·Phase 4·NCT01341275·400 enrolled

Immunogenicity8 trials

Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico

Completed·Sanofi·Phase 3·NCT03630705·525 enrolled

A Controlled Study to Evaluate the Safety and Immunogenicity of StreptAnova™ in Healthy Adults

Unknown status·—·Phase 1·NCT02564237·39 enrolled

Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults

Completed·—·Phase 1·NCT02126462·32 enrolled

Show 5 more trials

A Phase I Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00000745·72 enrolled

Systems Biology to Identify Biomarkers of Neonatal Vaccine Immunogenicity

Completed·—·N/A·NCT03246230·911 enrolled

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

Completed·Sanofi·Phase 3·NCT03537508·2,627 enrolled

Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

Completed·Sanofi·Phase 3·NCT03691610·950 enrolled

Immunogenicity of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared With PENTAXIM™ and ENGERIX B® at 2-3-4 Months Schedule

Completed·Sanofi·Phase 3·NCT00315055·310 enrolled

Immune System4 trials

Immune System Function Following Vaccination in HIV Infected Children Taking Anti-HIV Drugs

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00257127·101 enrolled

Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy

Terminated·NNational Cancer Institute (NCI)·Phase 2·NCT01339000·1 enrolled

Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00001119·288 enrolled

Show 1 more trial

A Study to Test If Giving Remune (an HIV Vaccine) Can Improve the Immune Systems of HIV-Positive Patients Who Are Also Participating in ACTG 328

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000943·50 enrolled

Children3 trials

Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children

Completed·—·Phase 1·NCT02839161·60 enrolled

A Phase Ib Trial of MSP 3 LSP in 1-2 Year Old Children in Burkina Faso

Unknown status·AAfrican Malaria Network Trust·Phase 1·NCT00452088·45 enrolled

Phase Ib Trial of MSP3 LSP in Children in Tanzania

Unknown status·AAfrican Malaria Network Trust·Phase 1·NCT00469651·45 enrolled

Immune Response3 trials

Evaluate Immune Response Approximately 5 to 6 Years After Receiving Different Formulations of GSK Bio Hep B Vaccine

Completed·GSK·Phase 4·NCT00329576·632 enrolled

Immune Response to Systemic and Mucosal Antigenic Challenge in the Presence of Vedolizumab

Completed·Takeda·Phase 1·NCT01981616·127 enrolled

Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults

Completed·HHIV Vaccine Trials Network·Phase 1·NCT02109354·202 enrolled

15 more indications

Papilloma2 trials

Dose-Ranging Study of Recombinant Human Papillomavirus Virus 16/18 Bivalent Vaccine

Completed·XXiamen University·Phase 2·NCT01356823·1,600 enrolled

Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts

Completed·UUniversity of Pretoria·Phase 3·NCT02750202·52 enrolled

Vaccination2 trials

HBV Vaccination in HIV-infected Adults

Unknown status·—·Phase 4·NCT03212911·96 enrolled

HBV Vaccination of Healthy Volunteers to Evaluate the Composition of Germinal Centers

Recruiting·RRockefeller University·Phase 4·NCT05272735·12 enrolled

Vaccine2 trials

A Study of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Infants and Toddlers

Completed·Sanofi·Phase 2·NCT01049035·580 enrolled

HBV Vaccine in Anti-core Positive Donors After LT

Unknown status·HHospital Clinic of Barcelona·Phase 2·NCT04442841·114 enrolled

Pediatric1 trial

Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

Completed·Sanofi·Phase 3·NCT03673462·2,797 enrolled

Respiratory Syncytial Virus1 trial

Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers

Terminated·Sanofi·Phase 3·NCT06397768·2,226 enrolled

Hepatitis1 trial

Clinical Trial of Recombinant Hepatitis E Vaccine

Completed·XXiamen University·Phase 3·NCT01014845·112,604 enrolled

Chronic Hepatitis1 trial

Combination Therapy With Interferon Plus Interleukin 2 and Hepatitis B Vaccine in Chronic Hepatitis B Patients

Completed·TTongji Hospital·Phase 4·NCT02360592·94 enrolled

HIV Seropositive1 trial

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Immuno-AG Recombinant HIV gp160 in Asymptomatic HIV Seropositive Individuals

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00000633·55 enrolled

Kidney Failure1 trial

Safety of HEPLISAV™ Hepatitis B Virus Vaccine in End-stage Kidney Failure Patients

Completed·DDynavax Technologies Corporation·Phase 1·NCT00426712·42 enrolled

Immunization1 trial

Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00013871·300 enrolled

Gene Expression1 trial

Pilot Study: Gene Expression Profiling of Immune Response to HBV Vaccination in Healthy Volunteers

Completed·RRockefeller University·N/A·NCT02055365·10 enrolled

Celiac Disease1 trial

Response to Hepatitis B Vaccine in Celiac Disease Patients

Terminated·SShaare Zedek Medical Center·N/A·NCT00739128·210 enrolled

Poliomyelitis1 trial

Study of Tetanus and Diphtheria Toxoids Adsorbed Combined With Component Pertussis Vaccine and Inactivated Poliomyelitis

Completed·Sanofi·Phase 2·NCT02040636·277 enrolled

Memory1 trial

Antibody Response and Immune Memory 15-18 Years After HBV Vaccination

Unknown status·NNational Taiwan University Hospital·N/A·NCT00172328

Chronic Hepatitis b1 trial

A Randomized, Open-Label, Multicenter Phase II Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Combination With Hepatitis B Vaccine or Pegylated Interferon α-2b (Peg-IFN) in Participants With HBeAg-Negative Chronic Hepatitis B (CHB) Treated With Nucleos(t)Ide Analogue (NAs)

Recruiting·AAusper Biopharma Co., Ltd.·Phase 2·NCT07069569·200 enrolled

Details

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