IV Ketamine

Phase 2Small molecule

MMinneapolis Veterans Affairs Medical Center

IV Ketamine is one of 98 small molecule programs targeting Treatment. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

TreatmentNot yet recruiting

Cognitive ImpairmentActive, not recruiting

TreatmentPhase 2

Not yet recruiting

Cognitive ImpairmentPhase 2

Active, not recruiting

Competition

Competitive Landscape

350 competitors in Treatment

#DrugCompanyPhaseTrials

Biltricide

Bayer

Preclinical

4 2

Alfenta

Jazz Pharmaceuticals

Preclinical

1 3

Niclocide

Bayer

Preclinical

1 4

Minipress

Pfizer

Preclinical

1 5

Theo-Dur

Pfizer

Preclinical

1 6

Emtriva

Gilead

Preclinical

1 7

Hivid

CConrado Roberto Hoffmann Filho

Preclinical

6 8

IV Ketamine

MMinneapolis Veterans Affairs Medical Center

Phase 2

1 9

Intuniv

PPromius Pharma, LLC

Preclinical

1 10

Clomid

Ferring

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Phase 2/3Recruiting

Sedation

NCT04195256

Q1 2027

Phase 2Not yet recruiting

Treatment

NCT06228391

Q4 2029

Recruiting

Major Depression

NCT06725277

Clinical

Trials by Indication[1]

Sedation2 trials

Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation

Recruiting·NNaveen Poonai·Phase 2/3·NCT04195256·400 enrolled

Intranasal Ketamine for Procedural Sedation

Unknown status·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 3·NCT02828566·470 enrolled

Renal Colic1 trial

Comparison of Treatment by IM Ketamine to IV Ketamine in Patients With Renal Colic

Unknown status·TTel-Aviv Sourasky Medical Center·Phase 3·NCT04013958·100 enrolled

Cognitive impairment1 trial

Single-dose Ketamine Treatment to Improve Depression in Mild Cognitive Impairment

Active, not recruiting·IIcahn School of Medicine at Mount Sinai·Phase 2·NCT06069843·15 enrolled

Abortion1 trial

Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion

Suspended·—·Phase 3·NCT03751423·123 enrolled

Treatment1 trial

Ketamine Treatment for PTSD and MDD in TBI

Not yet recruiting·MMinneapolis Veterans Affairs Medical Center·Phase 2·NCT06228391·40 enrolled

1 more indication

Major Depression1 trial

Comparative Effectiveness of Racemic Ketamine Versus Esketamine (Spravato®) for Depression: The OBSERVE Protocol

Recruiting·YYale University··NCT06725277·450 enrolled

Sources

References

[1]
ClinicalTrials.gov — 7 trial records for IV Ketamine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — IV Ketamine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for IV Ketamine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Minneapolis Veterans Affairs Medical Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: MMinneapolis Veterans Affairs Medical Center

IV Ketamine

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Q1 2027

Q4 2029

Trials by Indication[1]

Sedation2 trials

Renal Colic1 trial

Cognitive impairment1 trial

Abortion1 trial

Treatment1 trial

Major Depression1 trial

References

Drug Info

Quick Facts

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