Oxycodone HCl

PreclinicalSmall molecule

PPurdue Pharma LP

Oxycodone HCl is one of 6 small molecule programs targeting Analgesic Efficacy. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Analgesic EfficacyNot yet recruiting

Analgesic EfficacyPreclinical

Not yet recruiting

Competition

Competitive Landscape

8 competitors in Analgesic Efficacy

#DrugCompanyPhaseTrials

Advil

KKenvue Brands

Approved

4 2

Ultram

WWim Janssens

Approved

1 3

Journavx

Vertex Pharmaceuticals

Phase 3

1 4

Paracetamol

GSK

Phase 3

6 5

Acupan

YYonsei University

Preclinical

1 6

Oxycodone HCl

PPurdue Pharma LP

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2029

Phase 1Not yet recruiting

Opioid Use

NCT07218549

Clinical

Trials by Indication[1]

Oxycodone2 trials

Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children With Moderate to Severe Malignant and/ or Nonmalignant Pain Requiring Opioids

Completed·PPurdue Pharma LP·Phase 3·NCT01192295·155 enrolled

Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients

Completed·QQRxPharma Inc.·Phase 3·NCT01280331·375 enrolled

Efficacy and Safety2 trials

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Completed·QQRxPharma Inc.·Phase 3·NCT01016808·522 enrolled

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Completed·QQRxPharma Inc.·Phase 2·NCT00831051·197 enrolled

Low back pain2 trials

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Completed·PPurdue Pharma LP·Phase 3·NCT01427283·450 enrolled

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Completed·PPurdue Pharma LP·Phase 3·NCT01427270·455 enrolled

Analgesic Efficacy1 trial

Evaluating the Analgesic Efficacy of Oxycodone Hydrochloride in Pediatric Laparoscopic Cryptorchidism Surgery

Not yet recruiting·SShantou University Medical College·N/A·NCT06665048·162 enrolled

Abuse Potential1 trial

Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users

Completed·VViatris Specialty LLC·Phase 4·NCT05319756·54 enrolled

2 more indications

Acetaminophen1 trial

Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery

Completed·UUniversity of Southern California·Phase 2·NCT03111186·40 enrolled

Opioid Use1 trial

Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use

Not yet recruiting·CChristopher D. Verrico·Phase 1·NCT07218549·72 enrolled

Sources

References

[1]
ClinicalTrials.gov — 10 trial records for Oxycodone HCl. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Oxycodone HCl compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Oxycodone HCl. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Purdue Pharma LP company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: PPurdue Pharma LP

Oxycodone HCl

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2029

Trials by Indication[1]

Oxycodone2 trials

Efficacy and Safety2 trials

Low back pain2 trials

Analgesic Efficacy1 trial

Abuse Potential1 trial

Acetaminophen1 trial

Opioid Use1 trial

References

Drug Info

Quick Facts

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