Perineural dexamethasone

PreclinicalSmall molecule

Perineural dexamethasone is one of 19 small molecule programs targeting Postoperative Analgesia. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Postoperative AnalgesiaUnknown status

Postoperative AnalgesiaPreclinical

Unknown status

Competition

Competitive Landscape

23 competitors in Postoperative Analgesia

#DrugCompanyPhaseTrials

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Approved

15 2

Duragesic

CCephalon

Approved

4 3

Decadron

AAspen Global Incorporated

Approved

4 4

Nubain

AAultman Health Foundation

Approved

3 5

Celebrex

PPhiladelphia Eye Associates

Approved

1 6

EXPAREL

Pacira Pharmaceuticals, Inc

Approved

2 7

Intrathecal Morphine

Pacira Pharmaceuticals, Inc

Phase 3

5 8

Bupivacaine Only

Pacira Pharmaceuticals, Inc

Phase 3

4 9

Anrikefon

ZZhujiang Hospital

Phase 3

1 10

Fentanyl and Bupivacaine

HHospital Central Dr. Luis Ortega

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Dexamethasone1 trial

Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effects?

Completed·ZZealand University Hospital·Phase 2·NCT04817982·16 enrolled

Interscalene Brachial Plexus Block1 trial

The Effects of Dexamethasone on Low Dose Interscalene Brachial Plexus Block

Completed·—·Phase 4·NCT02322242·182 enrolled

Inflammatory Response1 trial

The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction

Recruiting·PPoznan University of Medical Sciences·Phase 4·NCT06789029·60 enrolled

Dexamethasone Administration1 trial

The Effect of Dexamethasone Administration Route in PENG Block for Pediatric Hip Surgery

Completed·PPoznan University of Medical Sciences·Phase 4·NCT06789367·60 enrolled

Total Hip Arthroplasty1 trial

The Effect of Dexamethasone Administration Route on Pain and Inflammatory Response in PENG Block for Total Hip Arthroplasty

Completed·PPoznan University of Medical Sciences·Phase 4·NCT06789328·60 enrolled

3 more indications

Shoulder Arthroscopy1 trial

Interscalene Block With Low-dose IV vs. Perineural Dexamethasone for Shoulder Arthroscopy

Completed·HHospital for Special Surgery, New York·Phase 4·NCT02506660·128 enrolled

Postoperative Analgesia1 trial

Nerve Blocks With Dexamethasone and Local Anaesthetic to Improve Postoperative Analgesia

Unknown status·—·N/A·NCT02436694·56 enrolled

Arm1 trial

The Effect of Dexamethasone Administration Route in Infraclavicular Brachial Plexus Block for Pediatric Arm and/or Hand Surgery

Completed·PPoznan University of Medical Sciences·Approved·NCT07061678·90 enrolled

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for Perineural dexamethasone. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Perineural dexamethasone compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Perineural dexamethasone. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Poznan University of Medical Sciences company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: PPoznan University of Medical Sciences

Perineural dexamethasone

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Dexamethasone1 trial

Interscalene Brachial Plexus Block1 trial

Inflammatory Response1 trial

Dexamethasone Administration1 trial

Total Hip Arthroplasty1 trial

Shoulder Arthroscopy1 trial

Postoperative Analgesia1 trial

Arm1 trial

References

Drug Info

Quick Facts

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