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Platelet Rich Fibrin

Phase 3Biologic

GGovernment Dental College and Research Institute, Bangalore

Platelet Rich Fibrin is one of 68 biologic programs targeting Stress urinary incontinence. It is currently in Phase 3.

3

Indications

28

Total Trials

5

Active Trials

67

Competitors

Pipeline

Status by Indication[3][1]

Indication

Stress Urinary IncontinenceActive, not recruiting

Chronic PeriodontitisActive, not recruiting

PeriodontitisActive, not recruiting

Stress Urinary IncontinencePhase 3

Active, not recruiting

Chronic PeriodontitisPhase 2

Active, not recruiting

PeriodontitisPhase 2

Active, not recruiting

Competition

Competitive Landscape

138 competitors in Periodontitis

#DrugCompanyPhaseTrials

Peridex

DDexcel Pharma Technologies Ltd.

Acanya

Curcumin

Calcium Hydroxide

MMansoura University

Platelet Rich Fibrin

GGovernment Dental College and Research Institute, Bangalore

Calcium Intravenous Infsuion

MMansoura University

Minocycline Hcl

Boswellia

MMansoura University

Metapex

AAga Khan University

Leddermix

MMansoura University

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Post-ApprovalNot yet recruiting

Surgery

NCT06776289

Clinical

Trials by Indication[1]

Platelet-rich Fibrin4 trials

Extraction and Socket Preservation Before Implant Placement Using Freezed Dried Allograft (FDBA) and Platelet-Rich Fibrin in Smokers

Completed·KKing Saud University·N/A·NCT05161455·40 enrolled

Platelet-rich Fibrin on Nerve Regeneration After Bilateral Sagittal Split Osteotomy

Unknown status·SShiraz University of Medical Sciences·N/A·NCT03159338·25 enrolled

Rosuvastatin Gel With 1:1 Mixture of Platelet-rich Fibrin and Bone Graft in Mandibular Degree II Furcation Defects

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 4·NCT02369250·110 enrolled

Show 1 more trial

Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth

Unknown status·—·N/A·NCT05608356·26 enrolled

Dental Implant2 trials

Impact of Biological Factors on Dental Implant

Not yet recruiting·—·N/A·NCT06037070·10 enrolled

Assessment of Keratinized Gingiva With and Without PRF Application in Patients With Dental Implant

Unknown status·UUniversity of Baghdad·Phase 3·NCT04864197·10 enrolled

Surgery2 trials

Endodontic Microsurgery

Not yet recruiting·MMark Schachman·Phase 4·NCT06776289·20 enrolled

Socket Seal Surgery

Completed·—·N/A·NCT06764732·45 enrolled

Chronic Periodontitis2 trials

PLATELET RICH FIBRIN COMBINED WITH 1.2% ATORVASTATIN FOR TREATMENT OF INTRABONY DEFECTS IN CHRONIC PERIODONTITIS

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2·NCT02119520·96 enrolled

Platelet Rich Fibrin Combined With Simvastatin for Treatment of Intrabony Defect in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2·NCT02120872·90 enrolled

Third Molar Surgery2 trials

Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo

Completed·CCeren Melahat Donmezer··NCT05678296·60 enrolled

Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.

Completed·BBeste Erismen··NCT06262945·60 enrolled

16 more indications

Healing1 trial

ASSESSMENT OF SOFT TISSUE HEALING OVER IMMEDIATELY PLACED IMPLANT SEALED WITH PLATELETS RICH FIBRIN (PRF) VERSUS DIODE LASER

Completed·NNourhan M.Aly·N/A·NCT05517733·16 enrolled

ESS1 trial

Clinical and Radiographic Assessment of PRF Versus Lutein Placement

Completed·MMansoura University·N/A·NCT06358352·30 enrolled

Bone Graft1 trial

PRF and Bone Graft in Endodontic Surgeries

Completed·SSaraswati Dental College·Phase 4·NCT04377698·20 enrolled

Quality of Life1 trial

The Effect of Periodontal Dressings and Various Materials on the Donor Site's Quality of Life After Free Gingival Graft Surgery

Recruiting·IIzmir Katip Celebi University·N/A·NCT06782035·36 enrolled

Mineral Trioxide Aggregate1 trial

Effectiveness of Mineral Trioxide Aggregate and Platelet Rich Fibrin Along With Biodentine. .

Completed·MMaharishi Markendeswar University (Deemed to be University)·Phase 4·NCT04773886·60 enrolled

Pain1 trial

Platelet Rich Fibrin VS Hyaloronic Acid in Management of Pain After Harvesting a Free Gingival Graft

Unknown status·Mmostafa soliman·N/A·NCT03814707·26 enrolled

Connective Tissue Graft1 trial

Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment

Completed·KKırıkkale University·N/A·NCT02397122·40 enrolled

Randomised Controlled Trial1 trial

Evaluation of Effect of Platelet-Rich Fibrin on Orthodontic Tooth Movement: a Split Mouth Randomised Controlled Trial

Recruiting·—·Phase 1/2·NCT06634017·15 enrolled

Endodontic Treatment1 trial

Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents

Unknown status·NNahda University·N/A·NCT05517187·40 enrolled

Treatment1 trial

Evaluation of Platelets Rich Fibrin and Nanohydroxyapatite in the Treatment of Intrabony Defects

Completed·KKing Abdulaziz University·Phase 1·NCT02810548·60 enrolled

Soft Tissue Augmentation1 trial

Clinical Evaluation of Soft Tissue Augmentation Using CTG and PRF Around Immediately Placed Dental Implants Versus Immediate Implant Alone in Esthetic Zone .

Completed·AAbeer hassan sharafuddin·N/A·NCT03413553·20 enrolled

Surgical1 trial

Injectable Platelet Rich Fibrin With Non Surgical Periodontal Therapy

Unknown status·IInstitute of Dental Sciences, Bareilly, Uttar Pradesh, India·N/A·NCT04070729·120 enrolled

Periodontitis1 trial

3-Month Clinical Trial of Liquid S-PRF in Periodontal Debridement for Periodontitis Stages II-IV

Recruiting·MMahsa University·Phase 2·NCT07293962·14 enrolled

Antibiotics1 trial

Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin

Completed·CCeren Melahat Donmezer··NCT04989127·75 enrolled

Stress urinary incontinence1 trial

Comparison Between Two Techniques in Treatment of Female Stress Urinary Incontinence

Completed·KKafrelsheikh University·Phase 3·NCT07366762·40 enrolled

Unspecified1 trial

Bioactive Glass and Platelet Rich Fibrin in Intrabony Defects

Completed·—·Phase 3·NCT02982681·10 enrolled

Sources

References

[1]
ClinicalTrials.gov — 28 trial records for Platelet Rich Fibrin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Platelet Rich Fibrin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Platelet Rich Fibrin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Government Dental College and Research Institute, Bangalore company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Biologic[2]
Highest Phase: Phase 3[1]
Company: GGovernment Dental College and Research Institute, Bangalore

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