Premarin

ApprovedSmall molecule

Pfizer

Premarin is one of 99 small molecule programs targeting Atrophic Vaginitis. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Atrophic VaginitisActive, not recruiting

Prostate CancerActive, not recruiting

Overactive BladderActive, not recruiting

Hot FlashesActive, not recruiting

Atrophic VaginitisPhase 1

Active, not recruiting

Prostate CancerPhase 2

Active, not recruiting

Overactive BladderApproved

Active, not recruiting

Hot FlashesPhase 2

Active, not recruiting

Competition

Competitive Landscape

1399 competitors in Prostate Cancer

#DrugCompanyPhaseTrials

Premarin

Pfizer

Approved

1 2

Novantrone

Pfizer

Preclinical

5 3

Trexall

Alnylam Pharmaceuticals

Preclinical

—4

Jatenzo

GGrupo Espanol de Tumores Neuroendocrinos

Preclinical

2 5

Ranexa

MMenarini International Operations Luxembourg SA

Preclinical

1 6

Viagra

VViatris Specialty LLC

Preclinical

1 7

Duragesic

CCephalon

Preclinical

1 8

Triptorelin Pamoate

Ipsen

Preclinical

2 9

Osmitrol

BB. Braun Medical Inc.

Preclinical

—10

Ifex

BBaxter Healthcare Corporation

Preclinical

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Estrogen Replacement Therapy2 trials

Beneficial Effects of Oral Premarin Estrogen Replacement Therapy Assessed by Human Genome Array

Completed·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 1·NCT00318318·20 enrolled

POETRY: Study of Estrogen Replacement Therapy in Postmenopausal Women With Parkinson's Disease

Completed·TThe Parkinson Study Group·Phase 2·NCT00234676·23 enrolled

Interaction1 trial

Study Evaluating Premarin and Bazedoxifene Potential Interaction

Completed· Pfizer logo

Pfizer·Phase 1·NCT00745173·30 enrolled

Postmenopausal Women1 trial

Study Comparing Four New Formulations for Premarin in Healthy Postmenopausal Women

Completed· Pfizer logo

Pfizer··NCT00380887·54 enrolled

Hot flashes1 trial

Treatment Of Hot Flashes/Flushes In Postmenopausal Women (WARM Study)

Completed· GSK logo

GSK·Phase 2·NCT00604825·356 enrolled

Preoperative1 trial

Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor

Completed·UUniversity of Texas Southwestern Medical Center·Phase 4·NCT01778985·30 enrolled

6 more indications

Treatment1 trial

Vaginal Estrogen With Pessary Treatment

Completed·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·N/A·NCT01843166·150 enrolled

Atrophic Vaginitis1 trial

Study Comparing Premarin® Vaginal Cream Versus Premarin® Oral Tablets in Atrophic Vaginitis

Completed· Pfizer logo

Pfizer·Phase 1·NCT00167921·24 enrolled

Post Operative Pain1 trial

Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?

Completed·SSunnybrook Health Sciences Centre··NCT03266926·140 enrolled

Prostate Cancer1 trial

Two Doses of Conjugated Estrogen (Premarin) in Patients With Androgen-Independent Prostate Cancer

Completed·—·Phase 2·NCT00134654·48 enrolled

Overactive Bladder1 trial

Premarin Versus Toviaz for Treatment of Overactive Bladder

Unknown status·TThe Cleveland Clinic·Phase 4·NCT01613170·90 enrolled

Surgery1 trial

Patient Adherence to Premarin Versus Vagifem Therapy After Female Pelvic Reconstructive Surgery

Withdrawn·UUniversity Hospitals Cleveland Medical Center·Phase 4·NCT02860897

Sources

References

[1]
ClinicalTrials.gov — 12 trial records for Premarin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Premarin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Premarin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Pfizer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Pfizer

Premarin

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Estrogen Replacement Therapy2 trials

Interaction1 trial

Postmenopausal Women1 trial

Hot flashes1 trial

Preoperative1 trial

Treatment1 trial

Atrophic Vaginitis1 trial

Post Operative Pain1 trial

Prostate Cancer1 trial

Overactive Bladder1 trial

Surgery1 trial

References

Drug Info

Quick Facts

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