Seroquel Xr

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Bipolar DisorderAnxietyPostpartum DepressionPanic Disorder

89 competitors in Bipolar Disorder

#DrugCompanyPhaseTrials

1

Geodon

Pfizer

Approved

72

Namenda

AbbVie

Approved

43

Risperdal

WWim Janssens

Approved

144

Trileptal

Novartis

Approved

35

Tegretol

Novartis

Approved

16

Zofran

Novartis

Approved

17

Ozempic

Novo Nordisk

Approved

18

Keppra

UCB

Approved

—9

Vraylar

AbbVie

Approved

—10

Ritalin

Novartis

Approved

—Show 46 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Schizophrenia5 trials

A 6-week Study to Evaluate the Efficacy and Safety of Lurasidone HCL in Acutely Psychotic Patients With Schizophrenia

Completed·BBukwang Pharmaceutical·Phase 3·NCT03465787·210 enrolled

Efficacy and Safety of SEROQUEL Extended Release (XR) in Acute Schizophrenia

Completed·AstraZeneca·Phase 4·NCT00954122·35 enrolled

Lurasidone HCl - A Long Term Phase 3 Study of Patients With Chronic Schizophrenia

Completed·Sumitomo Pharma America, Inc.·Phase 3·NCT00789698·240 enrolled

Show 2 more trials

A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia.

Completed·Otsuka·Phase 3·NCT04115319·305 enrolled

Lurasidone HCL - A 6-week Phase 3 Study of Patients With Acute Schizophrenia.

Completed·Sumitomo Pharma America, Inc.·Phase 3·NCT00790192·488 enrolled

Major Depressive Disorder4 trials

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder

Completed·Johnson & Johnson·Phase 3·NCT04338321·676 enrolled

Identifying Very Early Response to Seroquel Extended Release (XR) Augmentation for Major Depressive Disorder

Completed·SSunnybrook Health Sciences Centre·Phase 4·NCT00892463·26 enrolled

A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

Completed·Johnson & Johnson·Phase 2·NCT03321526·107 enrolled

Show 1 more trial

A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Completed·Johnson & Johnson·Phase 3·NCT04513912·757 enrolled

Generalized Anxiety Disorder2 trials

Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)

Completed·UUniversity Hospitals Cleveland Medical Center·Phase 3·NCT00671853·120 enrolled

Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Disorder

Terminated·KKeming Gao·Phase 3·NCT00868374·23 enrolled

TIA2 trials

Quetiapine XR in Schizophrenic Patients

Terminated·HHannover Medical School·Phase 3·NCT01071135·5 enrolled

Comparison of the Subjective Well-being and Tolerability of Quetiapine XR to Risperidone

Completed·AstraZeneca·Phase 3·NCT00600756·798 enrolled

Depression2 trials

The Quietude Study: Quetiapine Use for Agitated Depression

Terminated·PPhysicians Research And Education Network·Phase 3·NCT01363310·250 enrolled

Brain Imaging of Quetiapine Response in Anxious Depression

Completed·IIndiana University School of Medicine·Phase 4·NCT00982345·20 enrolled

15 more indications

Anxiety Disorder2 trials

Clinical Benefits of Seroquel XR in Anxiety Disorder

Unknown status·CCorporation de Recherche en Neuropsycho Pharmacologie de Quebec·Phase 3·NCT01672554·40 enrolled

Efficacy and Safety Study of Seroquel SR in the Treatment of Generalised Anxiety Disorder

Completed·AstraZeneca·Phase 3·NCT00389064·450 enrolled

Agitation1 trial

Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry

Unknown status·BBayside Health·Phase 4·NCT00986167·72 enrolled

Bipolar Disorder1 trial

Quetiapine XR for Cognitive and Functional Disability in Clinically Stable Patients With Bipolar Disorder

Terminated·EEmory University·Phase 4·NCT00746421·32 enrolled

Anxiety1 trial

Cardiovascular Biomarkers and Quetiapine in Depression and Anxiety Patients

Completed·LLoyola University·Phase 4·NCT00951483·91 enrolled

CAR1 trial

Schizophrenic Patients in Integrated Care

Terminated·AstraZeneca·Phase 4·NCT00681629·7 enrolled

Alcohol Abstinence1 trial

The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence

Completed·SSubhajit Chakravorty·Phase 3·NCT00434876·22 enrolled

Panic Disorder1 trial

A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients

Completed·IIndiana University·Phase 4·NCT00619892·26 enrolled

Specific Phobia1 trial

Quetiapine in Specific Phobia

Completed·UUniversity Hospital Muenster·Phase 2·NCT00872716·60 enrolled

Cognition1 trial

The Effects of Quetiapine XR on Cognition, Mood and Anxiety Symptoms in SSRI-Resistant Unipolar Depression

Completed·UUniversity of British Columbia·Phase 3·NCT00517387·64 enrolled

IPEX1 trial

Bipolar Study of Seroquel XR With Pramipexole Dihydrochloride

Completed·—·Phase 2·NCT00893841·96 enrolled

Postpartum Depression1 trial

Quetiapine in the Treatment of Postpartum Depression (PPD) in Bipolar Disorder (BD), Type II

Completed·—·N/A·NCT01527448·26 enrolled

Major Depression1 trial

Serotonin Transporter Genetic Variation and Amygdala Responses to Antidepressant Medications in Major Depression

Completed·UUniversity of Calgary·Phase 4·NCT02132286·57 enrolled

Double-blind1 trial

An Open Label, Double-blind Discontinuation Study of Quetiapine Extended Release(XR)

Terminated·—·Phase 1·NCT00606541·55 enrolled

Bipolar Depression1 trial

Pediatric Bipolar Depression

Completed·AstraZeneca·Phase 3·NCT00811473·193 enrolled

Monotherapy1 trial

Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients

Completed·AstraZeneca·Phase 3·NCT00789854·688 enrolled

Regulatory

FDA Approval Timeline[4]

Details

Drug Info

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