Setmelanotide is used to treat rare genetic forms of obesity caused by specific mutations in genes that control appetite and metabolism. It helps reduce weight and food cravings in people with these genetic conditions.[2] Imcivree is currently approved and in use across 6 indications[4].[1]
Imcivree is one of 81 peptide programs targeting Prader-Willi syndrome. It is currently in Approved.
Indications
Total Trials
Active Trials
Competitors
FDA Applications
NDA/BLA/ANDA regulatory filings
Patents
Pipeline
Competition
49 competitors in Morbid Obesity
Imcivree
Lovenox
Ozempic
Mounjaro
Precedex
Prilosec
Tylenol
Amoxil
Xylocaine
Arixtra
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Clinical
Regulatory
Nov 25, 2020
IMCIVREE
NDA NDA213793
Nov 25, 2020
IMCIVREE
NDA NDA213793
Nov 15, 2023
IMCIVREE
NDA NDA213793
Dec 20, 2024
IMCIVREE
NDA NDA213793
Aug 21, 2025
IMCIVREE
NDA NDA213793
Mar 19, 2026
IMCIVREE
NDA NDA213793
Sources