Flomax
(Tamsulosin)ApprovedSmall molecule
SanofiTamsulosin is used to treat urinary symptoms of an enlarged prostate, such as difficulty urinating, weak urine stream, and needing to urinate frequently or urgently.[2] Flomax is currently approved and in use across 27 indications[4].[1]
Flomax is one of 414 small molecule programs targeting Urinary retention. It is currently in Approved.
27
Indications
129
Total Trials
22
Active Trials
413
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
Pipeline
Status by Indication[4][1]
Indication
Showing 10 of 27 indications
Competition
Competitive Landscape
348 competitors in Prostate Cancer
#DrugCompanyPhaseTrials
1Flomax
SanofiApproved
Talzenna
PfizerPhase 3
Antiandrogen Therapy
UUniversity of Washington
Phase 3
Triptorelin Embonate
IpsenPhase 3
Androgen Deprivation Treatment
MMedical University of Vienna
Phase 3
Lupron Depot
RRepros Therapeutics Inc.
Phase 3
Trexall
Jazz PharmaceuticalsPreclinical
Duragesic
CCephalon
Preclinical
Ranexa
MMenarini International Operations Luxembourg SA
Preclinical
Botox
VVitae Pharmaceuticals Inc., an Allergan affiliate
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Benign Prostatic Hyperplasia25 trials
Show 22 more trials
Efficacy of Silodosin in the Treatment of Symptomatic Benign Prostatic Hyperplasia (BPH)
Completed·—·Phase 4·NCT04107896·141 enrolled
Urinary retention16 trials
Show 13 more trials
Tamsulosin to Prevent Postoperative Urinary Retention in Laparoscopic Inguinal Hernia Repair
Terminated·—·Phase 4·NCT04434378·170 enrolled
Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery
Recruiting·—·Phase 2·NCT04597372·154 enrolled
Treatment8 trials
Show 5 more trials
Behavior and Exercise Versus Drug Treatment in Men With Nocturia (BEDTiMe)
Completed·—·Phase 4·NCT00824200·72 enrolled
The Use of Tamsulosin in Treatment of (10-15 mm) Lower Ureteric Stones in Adults With Non-emergent Symptoms
Unknown status·—·Phase 1·NCT03274700·80 enrolled
Lower Urinary Tract Symptom5 trials
Show 2 more trials
Pilot Trial Of Urinary Nerve Growth Factor (NGF) As Biomarker for Male Lower Urinary Tract Symptoms
Completed·—·Phase 4·NCT01457573·10 enrolled
MPA4 trials
Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion
Not yet recruiting·TTaipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation·Phase 4·NCT07310797·500 enrolled
Effect of Tamsulosin on PE Compared With Paroxetine Hydrochloride
Unknown status·—·Phase 3·NCT03879746·160 enrolled
COMPARISON OF SILODOSIN AND TAMSULOSIN IN MEDICAL EXPULSIVE THERAPY OF DISTAL URETERIC CALCULI
Completed·—·Phase 1·NCT05790902·142 enrolled
Show 1 more trial
52 more indications
Hyperplasia3 trials
Shock3 trials
Can Acupoint Low Intensity Shockwave Therapy Improve Bladder Voiding Efficiency
Recruiting·—·N/A·NCT06020963·100 enrolled
Monotherapy2 trials
Fed2 trials
Renal Stones2 trials
Prospective2 trials
Efficacy and Safety2 trials
AIN2 trials
Prolonged2 trials
Fasting Conditions2 trials
TED2 trials
Emergency Department Patient2 trials
Overactive Bladder2 trials
Urolithiasis2 trials
Extracorporeal Shockwave Lithotripsy1 trial
Chronic Prostatitis1 trial
Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis
Unknown status·—·N/A·NCT00913315·30 enrolled
ESS1 trial
Tamsulosin Assisted Ureteral Access Sheath Insertion
Unknown status·—·Phase 3·NCT05197088·110 enrolled
Multiple Sclerosis1 trial
Efficacy of Alpha-blockers (Tamsulosin) in the Treatment of Symptomatic Dysuria in Multiple Sclerosis in Women
Recruiting·—·N/A·NCT05439902·60 enrolled
Prostate Cancer1 trial
A Pilot Study of Ultra-High-Dose Hypofractionated or Single-Dose Radiotherapy for Intermediate Risk Prostate Cancer
Active, not recruiting·—·Phase 2·NCT04147806·30 enrolled
Bladder Cancer1 trial
Comparison of Medical and Surgical Treatments of Benign Prostate Hyperplasia in Patients Who Have Low Grade Non Muscle Invasive Bladder Cancer for Tumour Recurrence and Progression
Unknown status·—·Phase 4·NCT02443844·40 enrolled
Surgery1 trial
Prostatectomy1 trial
Impact of Tamsulosin on Voiding Patterns Following Early Catheter Removal After Robot-assisted Laparoscopic Radical Prostatectomy
Unknown status·—·N/A·NCT01209988·220 enrolled
Voiding Dysfunction1 trial
Tics1 trial
Posterior Urethral Valve1 trial
Cardiovascular1 trial
Refractory1 trial
Randomized Controlled Trial1 trial
Effect of Perioperative Selective alpha1-blockers in Non-stented Ureteroscopic Laser Lithotripsy for Ureteric Stones: A Randomized Controlled Trial
Completed·—·Phase 3·NCT04557202·120 enrolled
Spine Surgery1 trial
Decreasing Rates of Intraurethral Catheterization Postoperatively in Spine Surgery
Completed·—·Phase 4·NCT02919436·610 enrolled
Safety and Efficacy1 trial
Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients with BPH.
Recruiting·—·Phase 2·NCT05401032·70 enrolled
Randomized1 trial
Silodosin vs Tamsulosin for LUTS Due to BPH: A Randomized Crossover Trial
Not yet recruiting·—·Phase 4·NCT07467343·140 enrolled
Drug1 trial
Double J Stent1 trial
Mydriasis1 trial
Medication1 trial
Clinical Trial1 trial
Chronic Kidney Disease (CKD)1 trial
Risk of Serious Adverse Events Associated With Tamsulosin Use in Older Adults With Advanced Chronic Kidney Disease: A Population-Based Cohort Study Research Protocol
Active, not recruiting·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's··NCT07274228·14,000 enrolled
Stent Related Symptoms1 trial
Tamsulosin1 trial
Unspecified4 trials
Silodosin vs Tamsulosin as MET
Unknown status·—·Phase 3·NCT05570084·80 enrolled
Show 1 more trial
Regulatory
FDA Approval Timeline[5]
Apr 15, 1997
FLOMAX
NDA NDA020579
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Flomax drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Tamsulosin. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]