Tolperisone

Phase 3Small molecule

NNeurana Pharmaceuticals, Inc.

Tolperisone is one of 53 small molecule programs targeting Muscle spasm. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Muscle SpasmActive, not recruiting

Low Back PainActive, not recruiting

Muscle SpasmPhase 3

Active, not recruiting

Low Back PainPhase 3

Active, not recruiting

Competition

Competitive Landscape

237 competitors in Low Back Pain

#DrugCompanyPhaseTrials

Tofranil

Sanofi

Phase 3

1 2

Sympazan

Lundbeck

Phase 3

1 3

Arcoxia

Novartis

Phase 3

1 4

Pred Forte

Suboxone

4 6

Tylenol

KKenvue Brands

Phase 3

3 7

Keterol

PPamukkale University

Phase 3

3 8

Botox

RRevance Therapeutics, Inc.

Phase 3

1 9

Detrol La

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Phase 3

1 10

Amoxil

GGlobal Antibiotics Research and Development Partnership

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Muscle spasm2 trials

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm

Completed·NNeurana Pharmaceuticals, Inc.·Phase 3·NCT04671082·1,004 enrolled

Tolperisone in Acute Muscle Spasm of the Back

Completed·NNeurana Pharmaceuticals, Inc.·Phase 2·NCT03802565·415 enrolled

Phase 11 trial

A Phase 1 PK Study of Tolperisone in Healthy Subjects

Completed·NNeurana Pharmaceuticals, Inc.·Phase 1·NCT04465266·27 enrolled

Cognitive Function1 trial

Effects of Tolperisone on Measures of Drowsiness and Cognitive Function

Completed·NNeurana Pharmaceuticals, Inc.·Phase 1·NCT04407377·39 enrolled

Low back pain1 trial

The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain and Sciatic Pain "BETA"

Active, not recruiting·SSemmelweis University·Phase 3·NCT05544656·150 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for Tolperisone. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Tolperisone compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Tolperisone. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Neurana Pharmaceuticals, Inc. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: NNeurana Pharmaceuticals, Inc.

Tolperisone

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Muscle spasm2 trials

Phase 11 trial

Cognitive Function1 trial

Low back pain1 trial

References

Drug Info

Quick Facts

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