Tranilast
Phase 3Small molecule
Tranilast is one of 18 small molecule programs targeting Esophageal stricture. It is currently in Phase 3.
2
Indications
12
Total Trials
2
Active Trials
17
Competitors
Pipeline
Status by Indication[3][1]
Competition
Competitive Landscape
17 competitors in Rosacea
#DrugCompanyPhaseTrials
1Vibramycin
PPfizer's Upjohn has merged with Mylan to form Viatris Inc.
Approved
Alphagan
NovartisApproved
Minocin
TTriax
Approved
Flagyl
DDePuy Orthopaedics
Approved
Retin-a
VValeant Pharmaceuticals
Approved
Avlosulfon
AAlmirall, S.A.
Approved
Stromectol
CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 3
Tofranil
SanofiPhase 2
Elavil
AstraZenecaPhase 2
Seysara
AAlmirall, S.A.
Approved
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Treatment2 trials
A Clinical Study of Tranilast in the Treatment of Mucinoses
Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 1·NCT03490708·56 enrolled
A Clinical Study of Tranilast in the Treatment of Scleredema Diabeticorum
Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 1·NCT03512873·56 enrolled
Rheumatoid Arthritis2 trials
Hyperuricemia2 trials
Esophageal stricture1 trial
Tranilast Vs. Steroids to Prevent Esophageal Stricture (TAPES) After Endoscopic Resection for Superficial Neoplasms
Not yet recruiting·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 2·NCT06643689·394 enrolled
LAM1 trial
Effect of Inflammasome Inhibitor on hsCRP in Patients After PCI
Completed·UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology·Phase 4·NCT05130892·132 enrolled
4 more indications
Nasopharyngeal Carcinoma1 trial
Rosacea1 trial
Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of Rosacea
Enrolling by invitation·SSecond Affiliated Hospital of Xi'an Jiaotong University·Phase 4·NCT06307288·45 enrolled
Sarcoidosis1 trial
A Clinical Study of Tranilast in the Treatment of Sarcoidosis
Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 1·NCT03528070·56 enrolled
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Tranilast. EMBL-EBI & Wellcome Sanger Institute.
- [4]
Details
Drug Info
Quick Facts
- Modality
- Small molecule[2]
- Highest Phase
- Phase 3[1]
- Company
- NNuon Therapeutics, Inc.