Triiodothyronine

ApprovedSmall molecule

HHadassah Medical Organization

Triiodothyronine is one of 153 small molecule programs targeting Hypothyroidism. It is currently in Approved.

Indications

Total Trials

Active Trials

152

Competitors

Pipeline

Status by Indication[3][1]

Indication

HypothyroidismActive, not recruiting

Breast CarcinomaActive, not recruiting

Adverse EffectActive, not recruiting

Septic ShockActive, not recruiting

Atrial FibrillationActive, not recruiting

HypothyroidismApproved

Active, not recruiting

Breast CarcinomaPhase 2

Active, not recruiting

Adverse EffectPreclinical

Active, not recruiting

Septic ShockPhase 2

Active, not recruiting

Atrial FibrillationPhase 1

Active, not recruiting

Competition

Competitive Landscape

376 competitors in Atrial Fibrillation

#DrugCompanyPhaseTrials

Triiodothyronine

HHadassah Medical Organization

Approved

1 2

Rituxan

Calan

4 4

Brukinsa

BBeOne Medicines

Preclinical

1 5

Imbruvica

PPharmacyclics LLC.

Preclinical

1 6

Ondexxya

UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology

Preclinical

1 7

Romazicon

CConrado Roberto Hoffmann Filho

Preclinical

1 8

Calcium

Eli Lilly

Preclinical

1 9

Low-Molecular-Weight Heparin

Daiichi Sankyo

Preclinical

1 10

SGLT2 Inhibitor

Eli Lilly

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Atrial Fibrillation1 trial

Study of T3 on the Incidence of Atrial Fibrillation in Patients Undergoing Cardiac Surgery

Completed·NNorthwell Health·Phase 1·NCT00289367·280 enrolled

Septic Shock1 trial

Thyroid Hormone Supplementation in Patients With Septic Shock

Completed·—·Phase 2·NCT05270798·108 enrolled

Depression1 trial

Triiodothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression.

Completed·HHadassah Medical Organization·Phase 3·NCT00158990·220 enrolled

Refractory Depression1 trial

Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression

Terminated·NNew York State Psychiatric Institute·Phase 4·NCT00296686·31 enrolled

Major Depression1 trial

Thyroid Medication and Antidepressants for Treating Major Depression

Completed·EEmory University·Phase 4·NCT00208702·153 enrolled

4 more indications

Hypothyroidism1 trial

Effect of T4-T3 Combination Therapy Versus T4 Monotherapy in Patients With Hypothyroidism

Completed·—·Phase 4·NCT00531713·59 enrolled

Adverse Effect1 trial

Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.

Completed·HHadassah Medical Organization·N/A·NCT00421369·35 enrolled

Cardiopulmonary Bypass1 trial

Oral Triiodothyronine for Children Undergoing Cardiopulmonary Bypass in Indonesia

Completed·NNational Cardiovascular Center Harapan Kita Hospital Indonesia·Phase 3·NCT02521168·177 enrolled

Breast Carcinoma1 trial

Study of Euthyroid Hypothyroxinemia in Metastatic Breast Carcinoma

Terminated·AAultman Health Foundation·Phase 2·NCT03787303·7 enrolled

Sources

References

[1]
ClinicalTrials.gov — 9 trial records for Triiodothyronine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Triiodothyronine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Triiodothyronine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Hadassah Medical Organization company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: HHadassah Medical Organization

Triiodothyronine

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Atrial Fibrillation1 trial

Septic Shock1 trial

Depression1 trial

Refractory Depression1 trial

Major Depression1 trial

Hypothyroidism1 trial

Adverse Effect1 trial

Cardiopulmonary Bypass1 trial

Breast Carcinoma1 trial

References

Drug Info

Quick Facts

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