Explore

Companies

Drugs

/

About·Data Management·Terms·Privacy

Stay informed

© 2026 VivoSeq. All rights reserved.

Musculoskeletal/Back Pain

Musculoskeletal

Back Pain

45

Pipeline Programs↗

150

Active Trials↗

73

Companies Involved↗

Back pain is a moderately active landscape with 45 programs across 73 companies. 3 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

72/100

Pipeline Velocity

90/100

Mech. Concentration

25/100

Completion Rate

88/100

Attrition Rate

7/100

Pipeline

Programs by Phase

Preclinical35

Lidocaine Hydrochloride

Citius Pharmaceuticals, Inc.

Naproxen Sodium

Bayer

Ketamine

Aultman Health Foundation

Local Anesthetic

Rennes University Hospital

Ketorolac

Javelin Pharmaceuticals

Phase 14

Psilocybin

COMPASS Pathways

Naloxone

Scienture

CNTX-3001

Centrexion Therapeutics

Sodium Aescinate

Xijing Hospital

Phase 23

Ketamine Hydrochloride

Boehringer Ingelheim

Diclofenac /ml

Aksaray University Training and Research Hospital

Psilocybin Therapy With Zolpidem

Joshua Woolley, MD, PhD

Phase 33

Rexlemestrocel-L

Mesoblast, Ltd.

Tolperisone

Neurana Pharmaceuticals, Inc.

Biofreeze

Sport and Spine Rehab Clinical Research Foundation

Approved

No programs

Analysis

Modality Breakdown

98%

Small molecule

40 of 41 classified programs — the dominant modality here.

Small molecule leads; the ring shows all 41 classified programs, each share of the total. Modality classified for 98% of 45 pipeline programs.

Analysis

Trial Status

472

clinical trials

Completed257 · 54%

Recruiting71 · 15%

Not yet recruiting50 · 11%

Unknown status29 · 6%

Active, not recruiting21 · 4%

Terminated20 · 4%

Other24 · 5%

Clinical Trials

Trial Activity

472 trials

The Prognostic Role of Central Sensitization in Short-Term Clinical Outcomes in Chronic Nonspecific Low Back Pain

Recruiting·Mardin Artuklu University·N/A·NCT07826546·180 enrolled

Back to Back: the Forgotten Role of Back Muscle Characteristics to Tailor Exercise Therapy for Recurrent Non-specific Low Back Pain

Recruiting·HHasselt University·N/A·NCT05851196·100 enrolled

Impact of Leisure Activities on Quality of Life in Patients With Chronic Low Back Pain

Recruiting·Centre Hospitalier Valida·N/A·NCT07467499·148 enrolled

Algorithm-informed Decision-making to Advance Pain Treatment (ADAPT Study)

Recruiting·UUniversity of Michigan·Preclinical·NCT07731750·500 enrolled

A Comparative Study of Erector Spinae Fascia (ESF) Injection and Dry Needling Combined With Functional Rehabilitation (FR) in Patients With Chronic Low Back Pain Who Have Undergone Spinal Surgery (SPIN-NEED)

Recruiting·CClinique de la Côte d'Emeraude·Preclinical·NCT07555496·120 enrolled

A Multi-Center Randomized Clinical Study of the NOCISCAN MR Spectroscopy (MRS) in Patients Treated for Discogenic Low Back Pain

Recruiting·AAclarion·N/A·NCT06661850·300 enrolled

Effectiveness of Ultrasound-guided Percutaneous Electrical Stimulation of the Inferior and Superior Gluteal Nerves as Treatment for Gluteus Maximus and Medius Muscle Dysfunction After an Episode of Low Back Pain: Randomized Clinical Trial

Recruiting·—·Preclinical·NCT06873386·24 enrolled

Influence of TECAR Therapy on Cervical Mobility and Functional Disability in Patients With Mechanical Neck Pain: Randomized Control Study

Recruiting·Batterjee Medical College·Preclinical·NCT07596953·40 enrolled

Ultrasound-guided Erector Spinae Plane (ESP) Block Versus Trigger Point Injection (TPI) for Chronic Thoracic Myofascial Pain: A Randomized Controlled Trial

Recruiting·MMayo Clinic·Approved·NCT07632820·76 enrolled

Fusion or Not- a Randomized Controlled Study on Low Back Pain

Recruiting·UUppsala University·Preclinical·NCT06709391·90 enrolled

Study of Correlation Between Serum BDNF Levels and Pfirmann Grading and IL- 1β

Recruiting·KKeimyung University Dongsan Medical Center·N/A·NCT07807839·59 enrolled

Psilocybin and Affective Function in Chronic Lower Back Pain Depression

Recruiting·JJohns Hopkins University·Phase 1·NCT06355414·40 enrolled

Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

Recruiting·BBoston Scientific Corporation·N/A·NCT06827262·1,500 enrolled

Comparing the Effects of Yoga Nidra, Yoga, and Control Condition on Thermal Pain Processing, Psychological Factors, and Movement-Evoked Pain in Individuals With Chronic Low Back Pain

Recruiting·University of Central Florida·Preclinical·NCT07543835·27 enrolled

Combined Effects of Post-Isometric Relaxation and Myofascial Release in Patients With Low Back Pain and Lower Cross Syndrome: A Randomized Controlled Trial

Recruiting·UUniversity of Karachi·Preclinical·NCT07496099·60 enrolled

Page 1 of 32

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)