local anesthetic

Phase 3Small molecule

RRennes University Hospital

local anesthetic is one of 124 small molecule programs targeting Hernia. It is currently in Phase 3.

Indications

Total Trials

Active Trials

123

Competitors

Pipeline

Status by Indication[3][1]

Indication

Lateral EpicondylitisActive, not recruiting

Frozen ShoulderActive, not recruiting

StrabismusActive, not recruiting

AnxietyActive, not recruiting

Back PainActive, not recruiting

Nitrous OxideCompleted

Peripheral Nerve BlockTerminated

BronchiectasisRecruiting

Lateral EpicondylitisPreclinical

Active, not recruiting

Frozen ShoulderPreclinical

Active, not recruiting

StrabismusPreclinical

Active, not recruiting

AnxietyPreclinical

Active, not recruiting

Back PainPreclinical

Active, not recruiting

Nitrous OxidePreclinical

Completed

Peripheral Nerve BlockPreclinical

Terminated

BronchiectasisPhase 3

Recruiting

Competition

Competitive Landscape

61 competitors in Anxiety

#DrugCompanyPhaseTrials

Versed

CConrado Roberto Hoffmann Filho

Approved

19 2

Lexapro

AbbVie

Approved

5 3

Ritalin

Novartis

Approved

3 4

Cymbalta

Jazz Pharmaceuticals

Approved

2 5

Buspar

Bristol-Myers Squibb

Approved

1 6

Neupro

UCB

Approved

1 7

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Approved

5 8

Xanax

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

5 9

Lyrica

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

5 10

Keppra

UCB

Approved

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Post-ApprovalRecruiting

Bronchiectasis

NCT06209047

Clinical

Trials by Indication[1]

Thoracic Surgery1 trial

Analgesia After Video-Assisted Thoracic Surgery

Completed·—·Phase 2·NCT05094323·102 enrolled

Sensorineural Hearing Loss1 trial

Assessment of The Efficacy of Intratympanic Platelet Rich Plasma for Treatment of Sensorineural Hearing Loss.

Unknown status·—·Phase 2/3·NCT05786378·23 enrolled

Bronchiectasis1 trial

Bronchoscopic Levofloxacin, Gentamicin, or Sham for Acute Exacerbation of Bronchiectasis

Recruiting·—·Phase 4·NCT06209047·315 enrolled

Regional Anesthesia1 trial

Systemic Nalbuphine Versus Intravenous Regional Anesthesia

Completed·—·N/A·NCT03150732·82 enrolled

Erector Spinae Plane Block1 trial

Ultrasound Guided Erector Spinae Plane Block in Breast Surgery

Unknown status·—·N/A·NCT03660020·60 enrolled

23 more indications

Ketamine1 trial

Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks

Unknown status·—·N/A·NCT04852484·90 enrolled

Back pain1 trial

Stem Cells vs. Steroids for Discogenic Back Pain

Withdrawn·JJohns Hopkins University·N/A·NCT04735185

Patient Satisfaction1 trial

Patient Satisfaction After Surgery for Otosclerosis Under Local ou General Anesthesia

Completed·RRennes University Hospital··NCT03888079·103 enrolled

Hernia1 trial

Predictive Factors for the Effectiveness of the Ilioinguinal Iliohypogastric Nerve Block for Hernia Surgery

Completed·UUniversity of Padova··NCT06121726·343 enrolled

Pilot Study1 trial

Cryoneurolysis for TKA - a Pilot Study

Unknown status·UUnity Health Toronto·N/A·NCT05286996·20 enrolled

Bupivacaine1 trial

Assessment of Systemic Pharmacokinetics of Levobupivacaine and Ropivacaine During Continuous Epidural Infusion

Completed·FFondazione IRCCS Policlinico San Matteo di Pavia·Phase 4·NCT01229241·181 enrolled

Lateral Epicondylitis1 trial

Comparing Autologous Blood, Corticosteroid, and Their Combined Injection for Treating Lateral Epicondylitis

Completed·IIstanbul Training and Research Hospital·N/A·NCT06236178·119 enrolled

Observational Study1 trial

Serratus Intercostal Block Versus Epidural Analgesia in Eventration: Prospective Observational Study

Completed·HHospital del Rio Hortega··NCT06014749·80 enrolled

Effectiveness1 trial

Microneedle Pretreatment as a Strategy to Improve the Effectiveness of Topical Anesthetics Formulations

Completed·UUniversity of Campinas, Brazil·Phase 1·NCT05267938·30 enrolled

Anxiety1 trial

Pain and Anxiety Evaluation in Children Using Different Techniques of Local Anesthesia for Dental Treatment

Completed·UUniversidade Estadual de Ponta Grossa·N/A·NCT03176446·210 enrolled

Endodontic Treatment1 trial

Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment

Completed·UUniversity of Washington·Phase 4·NCT05338671·35 enrolled

Nitrous Oxide1 trial

QUALHYBOM Hypnosis Versus Equimolar Mixture of Oxygen and Nitrous Oxide (MEOPA) During a Bone Marrow Biopsy: a Clinical, Controlled, Randomized, Multicenter Study

Completed·RRennes University Hospital·N/A·NCT05178849·180 enrolled

Diagnosis1 trial

Marker for FAI Diagnosis

Completed·IIstituto Ortopedico Rizzoli··NCT02880085·20 enrolled

Local Anesthesia1 trial

Local Anesthesia in Radial Catheterization

Unknown status·HHippocration General Hospital·Phase 4·NCT03072394·444 enrolled

Frozen Shoulder1 trial

Percutaneous Interruption of the Coracohumeral Ligament for the Treatment of Frozen Shoulder

Completed·—·N/A·NCT04549051·46 enrolled