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Other/Pain Control

Pain Control

14

Pipeline Programs↗

17

Active Trials↗

9

Companies Involved↗

Pain Control is an emerging landscape with 14 programs across 9 companies. 7 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

47/100

Pipeline Velocity

27/100

Mech. Concentration

50/100

Completion Rate

78/100

Attrition Rate

16/100

Pipeline

Programs by Phase

Preclinical7

Naproxen Sodium

Bayer

Celecoxib Plus Lidocaine

Aswan University Hospital

Oxycodone/acetaminophen 5

SWOG Cancer Research Network

Buffered Lidocaine

University of California, San Diego

Preprocedural Pain Control

University of California, San Diego

Phase 1

No programs

Phase 2

No programs

Phase 37

Oxycodone

Protega

Suzetrigine

Vertex Pharmaceuticals

Hydrocodone/acetaminophen

AbbVie

Morphine

Hikma Pharmaceuticals LLC

Ketorolac

Javelin Pharmaceuticals

Approved

No programs

Analysis

Trial Status

137

clinical trials

Completed80 · 58%

Unknown status18 · 13%

Terminated15 · 11%

Not yet recruiting10 · 7%

Withdrawn7 · 5%

Recruiting5 · 4%

Other2 · 1%

Clinical Trials

Trial Activity

137 trials

Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures

Recruiting·MMayo Clinic·Phase 4·NCT05076110·188 enrolled

Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements

Recruiting·UUniversity of California, San Diego·N/A·NCT06960317·204 enrolled

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Recruiting·SSt. Louis University·Phase 3·NCT03823534·60 enrolled

ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy

Recruiting·UUniversity of Tennessee Medical Center·N/A·NCT05024344·128 enrolled

Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine

Recruiting·—·N/A·NCT06471348·128 enrolled

Comparing Perioperative Outcomes in Pain Control

Active, not recruiting·UUniversity of California, San Diego·Phase 4·NCT05690282·100 enrolled

Effect of Ultrasound-Guided Serratus Anterior Plane Block on Postoperative Recovery Quality in Patients Undergoing Minimally Invasive Coronary Artery Bypass Grafting: A Single-Center, Randomized, Double-Blind Controlled Trial

Not yet recruiting·Chinese PLA General Hospital·Preclinical·NCT07877532·168 enrolled

Evaluating Suzetrigine for Pain Control Following TKA

Not yet recruiting·AAdventHealth·Phase 3·NCT07357376·210 enrolled

Meloxicam Versus Ibuprofen for Pain Control After Third Molar Exodontia in Adult Patients

Not yet recruiting·UUniversidad Austral de Chile·Phase 4·NCT06704113·68 enrolled

iPACK Block vs. Periarticular Infiltration for TKA Pain Control

Not yet recruiting·TTurgutlu State Hospital·N/A·NCT07267650·100 enrolled

Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement

Not yet recruiting·UUniversity of California, San Diego·N/A·NCT06974019·68 enrolled

Empathy Through Pain Control: Lidocaine Gel vs. Placebo Prior to IUD Placement

Not yet recruiting·UUniversity of California, San Diego·N/A·NCT06974032·68 enrolled

The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.

Not yet recruiting·UUniversity of Missouri-Columbia·Phase 4·NCT07365800·248 enrolled

Dinalbuphine Sebacate in Postoperative Pain Control After TKA

Not yet recruiting·TThammasat University·Phase 4·NCT07140510·100 enrolled

The Effect of Preoperative Gabapentin on Postoperative Pain Control and Analgesic Requirements Following Bariatric Surgery

Not yet recruiting·—·N/A·NCT07169006·102 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)