Dexmedetomidine bolus

ApprovedSmall molecule

KKasr El Aini Hospital

Dexmedetomidine bolus is one of 34 small molecule programs targeting Sedation. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

DeliriumActive, not recruiting

DexmedetomidineCompleted

DeliriumApproved

Active, not recruiting

DexmedetomidinePhase 2

Completed

Competition

Competitive Landscape

167 competitors in Delirium

#DrugCompanyPhaseTrials

Circadin

NNeurim Pharmaceuticals Ltd.

Phase 3

14 2

Victoza

Novo Nordisk

Phase 3

1 3

Neurontin

VViatris Specialty LLC

Phase 3

1 4

Intuniv

PPromius Pharma, LLC

Phase 3

1 5

Dexmedetomidine bolus

KKasr El Aini Hospital

Approved

2 6

Sodiumchloride

RRadboud University Medical Center

Phase 3

1 7

Rozerem

Takeda

Preclinical

6 8

Inapsine

Alnylam Pharmaceuticals

Preclinical

1 9

Anerem

AAcacia Pharma Ltd

Preclinical

7 10

Spravato

WWim Janssens

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Post-ApprovalRecruiting

Delirium

NCT07427446

Clinical

Trials by Indication[1]

Delirium2 trials

Dexmedetomidine-Midazolam vs. Ketamine-Midazolam on Emergence Delirium

Recruiting·KKasr El Aini Hospital·Phase 4·NCT07427446·50 enrolled

Emergency Delirium in Pediatrics Undergoing Tonsillectomy and Adenoidectomy

Unknown status·EEsraa Abdel Azez Soltan Mohamed Zayed·Phase 1·NCT06215768·100 enrolled

Dexmedetomidine2 trials

Dexmedetomidine and Nalbuphine as Analgesic Adjuvants to Bupivacaine in Superficial Cervical Block.

Not yet recruiting·KKasr El Aini Hospital·Phase 4·NCT06490614·30 enrolled

Effect of Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose on Hemodynamic Changes During Laryngoscopy and Tracheal Intubation in Adults. A Randomized Comparative Study.

Completed·KKasr El Aini Hospital·Phase 2·NCT06327399·70 enrolled

Sedation1 trial

A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation

Completed·MMontefiore Medical Center·Phase 4·NCT03255824·144 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for Dexmedetomidine bolus. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Dexmedetomidine bolus compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Dexmedetomidine bolus. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Kasr El Aini Hospital company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: KKasr El Aini Hospital

Dexmedetomidine bolus

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Trials by Indication[1]

Delirium2 trials

Dexmedetomidine2 trials

Sedation1 trial

References

Drug Info

Quick Facts

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