Halaven
(Eribulin Mesylate)Phase 3Small molecule
EisaiEribulin mesylate is used to treat certain types of advanced breast cancer and a rare type of cancer called liposarcoma. It works by stopping cancer cells from dividing and growing.[1] Halaven is currently being investigated across 7 indications[3], with its most advanced program in Phase 3.[1]
Halaven is one of 129 small molecule programs targeting Liposarcoma. It is currently in Phase 3.
7
Indications
70
Total Trials
11
Active Trials
128
Competitors
Pipeline
Status by Indication[3][1]
Indication
Competition
Competitive Landscape
706 competitors in Breast Cancer
#DrugCompanyPhaseTrials
1Halaven
EisaiPhase 3
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Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Breast Cancer36 trials
Show 33 more trials
A Randomized Phase II Study Of Eribulin Mesylate With or Without Pembrolizumab For Metastatic Hormone Receptor Positive Breast Cancer
Completed·—·Phase 2·NCT03051659·90 enrolled
Maintenance Treatment With Eribulin Mesylate Versus Observation in Triple Negative Breast Cancer Patients
Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 2·NCT04502680·100 enrolled
Eribulin Mesylate or Paclitaxel as First- or Second-Line Therapy in Treating Patients With Recurrent Stage IIIC-IV Breast Cancer
Suspended·—·Phase 3·NCT02037529·201 enrolled
Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate
Completed·—·Phase 2·NCT02581839·9 enrolled
Halaven Patient Registry (Metastatic Breast Cancer, MBC)
Unknown status·—··NCT03245112·500 enrolled
Eribulin Combined With Anlotinib in Metastatic HER2 Negative Breast Cancer
Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 2·NCT04624711·40 enrolled
Randomized, Open, Controlled, Multicenter Phase III Clinical Study of Fluzoparib in Combination With Apatinib Versus Investigator-Selected Chemotherapy for HRD-Positive/HER2-negative Advanced Breast Cancer
Recruiting·SSun Yat-Sen Memorial Hospital of Sun Yat-Sen University·Phase 3·NCT06255392·200 enrolled
Triple-Negative Breast Cancer3 trials
24 more indications
Metastatic1 trial
A Study Combining Eribulin Mesylate With Avelumab in Cisplatin Ineligible Metastatic Urothelial Cell Cancer Patients
Terminated·—·Phase 1·NCT03502681·6 enrolled
Advanced Solid Tumors1 trial
Cervical Cancer1 trial
Lymphoma1 trial
Metastatic Solid Tumors1 trial
Metastatic Prostate Cancer1 trial
Salivary Gland Cancer1 trial
Pancreatic Cancer1 trial
Non-Small Cell Lung Cancer1 trial
Fallopian Tube Cancer1 trial
Bladder Cancer1 trial
Recurrent Head and Neck Cancer1 trial
Liposarcoma1 trial
Metastatic Bladder Urothelial Carcinoma1 trial
Advanced Urothelial Carcinoma1 trial
Estrogen Receptor Negative1 trial
Metastatic Malignant Neoplasm1 trial
Ovarian Carcinosarcoma1 trial
Anatomic Stage III Breast Cancer AJCC v81 trial
Locally Advanced Bladder Urothelial Carcinoma1 trial
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Eribulin Mesylate. EMBL-EBI & Wellcome Sanger Institute.
- [4]