IV Ketorolac

Phase 3Small molecule

CCumberland Pharmaceuticals

IV Ketorolac is one of 90 small molecule programs targeting Hysterectomy. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

HysterectomyActive, not recruiting

Colorectal CancerActive, not recruiting

Extracorporeal Shockwave LithotripsyNot yet recruiting

HysterectomyPreclinical

Active, not recruiting

Colorectal CancerPreclinical

Active, not recruiting

Extracorporeal Shockwave LithotripsyPhase 3

Not yet recruiting

Competition

Competitive Landscape

268 competitors in Colorectal Cancer

#DrugCompanyPhaseTrials

Trifluridine/tipiracil

AbbVie

Phase 3

3 2

Telisotuzumab Adizutecan

AbbVie

Phase 3

2 3

XL092

Roche

Phase 3

1 4

TAS 102

Taiho Oncology, Inc.

Phase 3

8 5

Huaier Granule

QQidong Gaitianli Medicines Co., Ltd

Phase 3

4 6

Cytokine-Induced Killer Cells

TThe First People's Hospital of Changzhou

Phase 3

2 7

PD-1 Monoclonal Antibody

SSichuan Baili Pharmaceutical Co., Ltd.

Phase 3

2 8

IBI363

Innovent Biologics (Suzhou) Co. Ltd.

Phase 3

1 9

IV Ketorolac

CCumberland Pharmaceuticals

Phase 3

1 10

TQB2102

CChia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Post-ApprovalNot yet recruiting

Extracorporeal Shockwave Lithotripsy

NCT07368738

Clinical

Trials by Indication[1]

Pain Control2 trials

Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

Completed·CCumberland Pharmaceuticals·Phase 4·NCT01901393·100 enrolled

A Pilot Study to Determine the Efficacy of Intravenous Ibuprofen for Pain Control Following Arthroscopic Knee Surgery

Completed·CCumberland Pharmaceuticals·Phase 4·NCT01650519·51 enrolled

Analgesic Efficacy2 trials

Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic

Completed·VValleywise Health·N/A·NCT02268955·22 enrolled

A Pilot Study Comparing the Analgesic Efficacy of IV Ibuprofen and IV Ketorolac

Unknown status·CCulpeper Surgery Center·Phase 4·NCT01514175·50 enrolled

Hysterectomy1 trial

Low Dose Versus Normal Dose Ketorolac for Postoperative Pain After Prostatectomy and Hysterectomy

Completed·JJessa Hospital·N/A·NCT05206110·100 enrolled

Indomethacin1 trial

Rectal Indomethacin vs Intravenous Ketorolac

Completed·—·Phase 4·NCT05664074·192 enrolled

Colorectal Cancer1 trial

IV Ibuprofen vs Ketorolac in Post Operative Pain in Colorectal Cancer Surgeries in Obese Patient

Completed·—·N/A·NCT05782608·50 enrolled

7 more indications

Bunion1 trial

Maxigesic IV Phase 3 Bunionectomy Study

Completed·AAFT Pharmaceuticals, Ltd.·Phase 3·NCT02689063·276 enrolled

Procedural Pain1 trial

Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure

Completed·UUniversity of California, Los Angeles·Phase 4·NCT02227316·40 enrolled

Premature Infants1 trial

Comparison of Oral and Intravenous Ibuprofen for PDA Treatment in Premature Infants

Unknown status·—·Phase 1/2·NCT01149564·70 enrolled

Orthopedic Trauma1 trial

Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients

Completed·—·Phase 4·NCT02152163·99 enrolled

Extracorporeal Shockwave Lithotripsy1 trial

Intravenous Acetaminophen and Ketorolac for Pain Management During Extracorporeal Shockwave Lithotripsy

Not yet recruiting·HHorizon Health Network·Phase 4·NCT07368738·266 enrolled

Ketorolac1 trial

Effect of Postoperative Ketorolac on Bone Healing After Joint Fusion

Unknown status·RRothman Institute Orthopaedics·Phase 3·NCT04872283·140 enrolled

Efficacy and Safety1 trial

Efficacy and Safety of IV Diclofenac (DIV075V)for Pain After Elective Orthopedic Surgery

Completed· Pfizer logo

Pfizer·Phase 3·NCT00507026·277 enrolled

Sources

References

[1]
ClinicalTrials.gov — 14 trial records for IV Ketorolac. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — IV Ketorolac compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for IV Ketorolac. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Cumberland Pharmaceuticals company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: CCumberland Pharmaceuticals

IV Ketorolac

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Trials by Indication[1]

Pain Control2 trials

Analgesic Efficacy2 trials

Hysterectomy1 trial

Indomethacin1 trial

Colorectal Cancer1 trial

Bunion1 trial

Procedural Pain1 trial

Premature Infants1 trial

Orthopedic Trauma1 trial

Extracorporeal Shockwave Lithotripsy1 trial

Ketorolac1 trial

Efficacy and Safety1 trial

References

Drug Info

Quick Facts

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