Lactoferrin

ApprovedSmall molecule

UUniversità degli Studi di Ferrara

Lactoferrin is one of 230 small molecule programs targeting Neonatal sepsis. It is currently in Approved.

Indications

Total Trials

Active Trials

229

Competitors

Pipeline

Status by Indication[3][1]

Indication

Neonatal SepsisActive, not recruiting

Bacterial VaginosisActive, not recruiting

PneumoniaActive, not recruiting

SepsisApproved

Iron Deficiency AnemiaActive, not recruiting

RhabdomyolysisActive, not recruiting

AnemiaActive, not recruiting

Heart FailureActive, not recruiting

COVID-19Active, not recruiting

Chronic Kidney DiseaseActive, not recruiting

Neonatal SepsisApproved

Active, not recruiting

Bacterial VaginosisPhase 2/Phase 3

Active, not recruiting

PneumoniaPreclinical

Active, not recruiting

SepsisApproved

Approved

Iron Deficiency AnemiaApproved

Active, not recruiting

RhabdomyolysisApproved

Active, not recruiting

AnemiaApproved

Active, not recruiting

Heart FailureApproved

Active, not recruiting

COVID-19Phase 2/Phase 3

Active, not recruiting

Chronic Kidney DiseaseApproved

Active, not recruiting

Showing 10 of 11 indications

Competition

Competitive Landscape

1931 competitors in COVID-19

#DrugCompanyPhaseTrials

Lactoferrin

UUniversità degli Studi di Ferrara

Approved

1 2

Stivarga

Bayer

Preclinical

1 3

Aimovig

Amgen

Preclinical

1 4

Calciferol

Alnylam Pharmaceuticals

Activella

Aquasol E

NNational Eye Institute (NEI)

Preclinical

1 7

Proventil

Mylan Pharmaceuticals Inc

Preclinical

1 8

Rayaldee

OOrganon and Co

Preclinical

1 9

Statins

Sanofi

Preclinical

1 10

Olokizumab

UCB

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2027

Post-ApprovalNot yet recruiting

Heart Failure

NCT06427200

Clinical

Trials by Indication[1]

Iron deficiency anemia4 trials

Lactoferrin for Treatment of Iron Deficiency Anemia.

Completed·—·Phase 4·NCT04435574·90 enrolled

Lactoferrin Alone ,Iron Alone Vs Lactoferrin Plus Iron for Treatment of Iron Deficiency Anemia

Completed·EEgymedicalpedia·N/A·NCT06590831·399 enrolled

Lactoferrin Versus Ferrous Sulfate in Management of Iron Deficiency Anemia Among Female Medical Ain Shams Students

Completed·Yyasmin gamal el gendy·Phase 2/3·NCT03940430·90 enrolled

Show 1 more trial

the Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis

Unknown status·SSouth Valley University·Phase 4·NCT03748043·100 enrolled

Pregnancy3 trials

Oral Lactoferrin Versus Iron Supplementation During Pregnancy

Completed·SSouth Valley University·Phase 4·NCT03542825·300 enrolled

Lactoferrin Versus Ferrous Sulphate for Treatment of Iron Deficiency Anaemia During Pregnancy

Completed·—·Phase 2·NCT03481790·200 enrolled

Lactoferrin Versus Ferrous Sulfate in Iron-deficiency During Pregnancy

Completed·—·Phase 2·NCT03759353·98 enrolled

Pneumonia1 trial

Effect of Lactoferrin in Pneumonia Treatment

Unknown status·—·N/A·NCT05431023·72 enrolled

Sepsis1 trial

Metformin and Lactoferrin in Sepsis in Icu

Recruiting·TTanta University·Phase 2/3·NCT06181422·60 enrolled

Anemia1 trial

Effect of Lactoferrin Versus Intravenous Iron Sucrose in Treatment of Anemia

Unknown status·—·Phase 4·NCT05921968·100 enrolled

13 more indications

Children1 trial

Comparative Study Between Oral Liposomal Iron,Iron Supported Lactoferrin and IV Iron Dextran in CKD Children

Unknown status·MMenoufia University·Phase 4·NCT05714176·90 enrolled

Rhabdomyolysis1 trial

Lactoferrin Effect on Kidney and Heart of Rhabdomyolysis Rats

Completed·—·Phase 4·NCT06491394·24 enrolled

Complication1 trial

Influence of Vaginal Lactoferrin on Amniotic Fluid Cytokines to Avoid Pregnancy Complications

Completed·UUniversità degli Studi di Ferrara·N/A·NCT02843984·60 enrolled

Inflammatory Mediators1 trial

Effects of Vaginal Lactoferrin Administration Prior to Genetic Amniocentesis on Inflammatory Mediators

Completed·UUniversità degli Studi di Ferrara·Phase 2·NCT02695563·111 enrolled

COVID-191 trial

Utility of Lactoferrin as an Adjunct Therapeutic Agent for COVID-19

Unknown status·—·Phase 2/3·NCT04421534·150 enrolled

Neonatal sepsis1 trial

Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis

Completed·—·Phase 4·NCT02959229·180 enrolled

Safety and Efficacy1 trial

Safety and Efficacy of Oral Bovine Lactoferrin

Completed·—·Phase 1·NCT04094597·200 enrolled

Heart Failure1 trial

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Not yet recruiting·—·Phase 4·NCT06427200·114 enrolled

Diarrhea1 trial

Recombinant Human Lactoferrin Administered Orally for the Prevention of Antibiotic Associated Diarrhea in Adult Patients

Unknown status·VVentria Bioscience·Phase 3·NCT01382199·340 enrolled

Chronic Kidney Disease1 trial

Effect of Adding Lactoferrin on Oral Iron on Anemia in Chronic Kidney Disease Patients

Unknown status·—·Phase 4·NCT05900635·60 enrolled

Newborns1 trial

Supplementation With Lactoferrin in Preterm Newborns

Completed·UUniversity of Siena·Phase 4·NCT01172236·1,300 enrolled

Bacterial Vaginosis1 trial

Role of Oral Lactoferrin in Prevention of Recurnt Bacterial Vaginosis in Pregnancy

Unknown status·ZZagazig University·Phase 2/3·NCT05669963·66 enrolled

Critical Illness1 trial

The Effect of Lactoferrin in Improving Clinical Outcomes in ICU Patients

Completed·MMansoura University Hospital·Approved·NCT05936528·660 enrolled

Sources

References

[1]
ClinicalTrials.gov — 23 trial records for Lactoferrin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Lactoferrin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Lactoferrin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Università degli Studi di Ferrara company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: UUniversità degli Studi di Ferrara

Lactoferrin

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2027

Trials by Indication[1]

Iron deficiency anemia4 trials

Pregnancy3 trials

Pneumonia1 trial

Sepsis1 trial

Anemia1 trial

Children1 trial

Rhabdomyolysis1 trial

Complication1 trial

Inflammatory Mediators1 trial

COVID-191 trial

Neonatal sepsis1 trial

Safety and Efficacy1 trial

Heart Failure1 trial

Diarrhea1 trial

Chronic Kidney Disease1 trial

Newborns1 trial

Bacterial Vaginosis1 trial

Critical Illness1 trial

References

Drug Info

Quick Facts

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