Aquasol E
(Vitamin E)ApprovedSmall molecule
Vitamin E is used to prevent and treat vitamin E deficiency, and may help protect cells from damage caused by free radicals. It's also sometimes used to support heart health and immune function.[2] Aquasol E is currently approved and in use across 77 indications[4].[1]
Aquasol E is one of 1595 small molecule programs targeting Hepatic steatosis. It is currently in Approved.
77
Indications
65
Total Trials
3
Active Trials
1,594
Competitors
Pipeline
Status by Indication[4][1]
Indication
Showing 10 of 76 indications
Competition
Competitive Landscape
2828 competitors in Breast Cancer
#DrugCompanyPhaseTrials
1Aquasol E
NNational Eye Institute (NEI)
Approved
Tykerb
GSKPreclinical
Adriamycin
GGynecologic Oncology Group
Preclinical
Avastin
BBio-Thera Solutions
Preclinical
Gemzar
GGynecologic Oncology Group
Preclinical
Voltaren
NovartisPreclinical
Zoladex
Luye Pharma Group Ltd.Preclinical
Neoadjuvant Therapy
SSun Yat-sen University
Preclinical
Apatinib Mesylate
BBukwang Pharmaceutical
Preclinical
Neoadjuvant Treatment
SShanghai Zhongshan Hospital
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Hepatitis2 trials
Non-Alcoholic Fatty Liver Disease2 trials
Acute Kidney Injury2 trials
Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization
Unknown status·RRajaie Cardiovascular Medical and Research Center·Phase 3·NCT03755700·1,000 enrolled
Prostate Cancer2 trials
54 more indications
Diabetic Macular Edema2 trials
Surgical Site Infection1 trial
Preeclampsia1 trial
The Correlation Between Vitamin A / E Levels and Preeclampsia
Unknown status·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·N/A·NCT03971604·300 enrolled
Iron deficiency anemia1 trial
Respiratory tract infection1 trial
The Effect of Vitamin E Supplementation on Hospital Stay Duration in Non-cyanotic Heart Disease Children With Lower Respiratory Tract Infections
Not yet recruiting·—·Phase 4·NCT06926712·260 enrolled
Type 2 Diabetes Mellitus1 trial
A Study of Chiglitazar in Patients With Metabolic Dysfunction-associated Steatohepatitis and Type 2 Diabetes Mellitus
Not yet recruiting·SShanghai Jiao Tong University School of Medicine·Phase 2·NCT07303803·300 enrolled
Primary Ovarian Insufficiency1 trial
Clinical Efficacy Analysis of Resveratrol in the Treatment of Primary Ovarian Insufficiency
Unknown status·—·N/A·NCT05410093·150 enrolled
Psoriasis Vulgaris1 trial
Using Acetylcysteine and Vitamin E With Psoriasis Vulgaris
Unknown status·—·Phase 3·NCT05906498·60 enrolled
Efficacy1 trial
Vitamin E Efficacy in HI/HA
Withdrawn·—·Phase 2·NCT04984798
Age-Related Macular Degeneration1 trial
Epilepsy1 trial
Non-Alcoholic Steatohepatitis1 trial
Atherosclerosis1 trial
Effect of High Dose Vitamin E on Carotid Atherosclerosis
Completed·NNational Center for Complementary and Integrative Health (NCCIH)·Phase 2·NCT00010699·120 enrolled
Colorectal Polyps1 trial
Oxidative Stress1 trial
A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants
Completed·—·Phase 2·NCT01495260·13 enrolled
Alcoholic Fatty Liver Disease1 trial
An Investigator Initiated Prospective, Four Arms Randomized Comparative Study of Efficacy and Safety of Saroglitazar, Vitamin E and Life Style Modification in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)/ Non-alcoholic Steatohepatitis (NASH)
Unknown status·—·Phase 3·NCT04193982·250 enrolled
Peyronie's Disease1 trial
Cardiovascular Disease1 trial
Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer
Completed·—·Phase 3·NCT00000479·39,876 enrolled
Retinopathy of Prematurity1 trial
Toxicity1 trial
The Impact of Pentoxifylline and Vitamin E on Radiotherapy-induced Toxicity in Head & Neck Cancer Patients
Completed·—·Phase 2·NCT02397486·60 enrolled
Preoperative1 trial
Cardiovascular1 trial
Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)
Completed·—·Phase 2·NCT00000541
Carotid Artery Plaque1 trial
Gaucher Disease1 trial
Role of Vitamin E in Gaucher Disease Patients
Completed·—·Phase 3·NCT06211478·40 enrolled
Restless Legs Syndrome1 trial
Endothelial Dysfunction1 trial
Polyp1 trial
Endothelial Monocyte-activating Polypeptide-II in Egyptian Sickle Patients
Completed·—·Phase 4·NCT03903133·50 enrolled
Metastatic Colorectal Cancer1 trial
Hemoglobin1 trial
Effect of Vitamin E Supplementation on Hemoglobin Levels in Healthy Adults
Completed·—·Phase 1/2·NCT02181348·357 enrolled
Drug1 trial
Retinitis Pigmentosa1 trial
Ulcerative Colitis1 trial
Dysmenorrhea1 trial
Keratosis1 trial
Effect of Vitamin E on Skin Aerobic Bacteria in Palmar Arsenical Keratosis
Completed·—·Phase 2·NCT02468518·45 enrolled
Unspecified1 trial
Vitamin E Dosing Study
Completed·NNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 2·NCT04801849·200 enrolled
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Aquasol E drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Vitamin E. EMBL-EBI & Wellcome Sanger Institute.
- [5]
Details
Drug Info
Quick Facts
- Modality
- Small molecule[3]
- Highest Phase
- Approved[1]
- Company
- NNational Eye Institute (NEI)