Lidocaine HCl

Phase 3Small molecule

MMayo Clinic

Lidocaine HCl is one of 10 small molecule programs targeting Radiculopathy. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

RadiculopathyActive, not recruiting

This Study Will Focus on in-Office Dermatological ProceduresNot yet recruiting

RadiculopathyPreclinical

Active, not recruiting

This Study Will Focus on in-Office Dermatological ProceduresPhase 3

Not yet recruiting

Competition

Competitive Landscape

12 competitors in Radiculopathy

#DrugCompanyPhaseTrials

Epidiolex

Advil

1 3

Trental

VValidus Pharmaceuticals

Approved

1 4

Kenalog

BBausch Health Americas, Inc.

Approved

—5

Lyrica

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Kenalog

Marcaine

Lidocaine HCl

1 9

Catapres

Boehringer Ingelheim

Preclinical

1 10

Aristospan

EEthypharm

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

ApprovedNot yet recruiting

This Study Will Focus on in-Office Dermatological Procedures

NCT07724418

Clinical

Trials by Indication[1]

Radiculopathy1 trial

Epidural Clonidine for Lumbosacral Radiculopathy

Terminated·MMayo Clinic·N/A·NCT00588354·26 enrolled

Pain Control1 trial

Lidocaine Jelly for Pain Control During Mohs Surgery

Completed·MMayo Clinic·Phase 4·NCT03595449·233 enrolled

Sore Throat1 trial

Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness of

Completed·TTehran University of Medical Sciences·Phase 3·NCT02114021·99 enrolled

Bunion1 trial

Open-Label CA-008 (Vocacapsaicin) in Bunionectomy

Completed·CConcentric Analgesics·Phase 2·NCT03885596·36 enrolled

Neuropathic Pain1 trial

Efficacy and Safety of Lidocaine Infusion Treatment in Management of Neuropathic Pain

Unknown status·SSeoul National University Hospital·Phase 2·NCT02597257·44 enrolled

1 more indication

This Study Will Focus on In-office Dermatological Procedures1 trial

Characterizing and Comparing the Duration of Local Anesthetic in Dermatologic Surgery

Not yet recruiting·WWeill Medical College of Cornell University·Approved·NCT07724418·50 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Lidocaine HCl. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Lidocaine HCl compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Lidocaine HCl. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Mayo Clinic company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: MMayo Clinic

Lidocaine HCl

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2027

Trials by Indication[1]

Radiculopathy1 trial

Pain Control1 trial

Sore Throat1 trial

Bunion1 trial

Neuropathic Pain1 trial

This Study Will Focus on In-office Dermatological Procedures1 trial

References

Drug Info

Quick Facts

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