Minocycline HCl

Phase 3Small molecule

OOraPharma

Minocycline HCl is one of 24 small molecule programs targeting Peri-Implantitis. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Peri-ImplantitisActive, not recruiting

PeriodontitisActive, not recruiting

Peri-ImplantitisPhase 3

Active, not recruiting

PeriodontitisPhase 3

Active, not recruiting

Competition

Competitive Landscape

138 competitors in Periodontitis

#DrugCompanyPhaseTrials

Peridex

DDexcel Pharma Technologies Ltd.

Phase 3

10 2

Acanya

Pfizer

Phase 3

1 3

Curcumin

Merck & Co.

Phase 3

1 4

Calcium Hydroxide

MMansoura University

Phase 3

2 5

Atorvastatin Calcium

Merck & Co.

Phase 2

1 6

Calcium Intravenous Infsuion

MMansoura University

Phase 3

2 7

Minocycline HCl

OOraPharma

Phase 3

1 8

Metapex

AAga Khan University

Phase 3

1 9

Boswellia

MMansoura University

Phase 3

1 10

ST266

NNoveome Biotherapeutics, formerly Stemnion

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Minocycline3 trials

Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg

Completed·UUniversity of Minnesota·Phase 4·NCT03762915·70 enrolled

Long-term Safety of Minocycline in Patients With Gum Disease

Completed·OOraPharma·Phase 4·NCT00668746·35 enrolled

Lycopene vs Minocycline Hydrochloride as Adjunctive to Periodontal Treatment

Unknown status·UUniversity of Baghdad·Phase 2·NCT03964935·30 enrolled

Peri-Implantitis2 trials

Arestin - Use in Subjects With Peri-Implantitis

Completed·OOraPharma·Phase 3·NCT01539564·215 enrolled

Arestin - Use in Subjects With Peri-Implantitis (With Subgingival Microbiological Evaluation)

Completed·OOraPharma·Phase 3·NCT01517334·208 enrolled

Periodontitis1 trial

Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis

Completed·OOraPharma·Phase 3·NCT00371332·128 enrolled

Dental Implant1 trial

Antibiotic Study for Dental Implants

Completed·OOraPharma·Phase 3·NCT00662532·44 enrolled

Sources

References

[1]
ClinicalTrials.gov — 7 trial records for Minocycline HCl. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Minocycline HCl compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Minocycline HCl. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — OraPharma company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: OOraPharma

Minocycline HCl

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Minocycline3 trials

Peri-Implantitis2 trials

Periodontitis1 trial

Dental Implant1 trial

References

Drug Info

Quick Facts

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