Calcium hydroxide
Phase 3Small molecule
Calcium hydroxide is used in dentistry to treat tooth decay, disinfect root canals, and promote healing inside teeth. It's also used in some medical settings to neutralize acids and promote bone healing.[1] Calcium hydroxide is currently being investigated across 5 indications[3], with its most advanced program in Phase 3.[1]
Calcium hydroxide is one of 67 small molecule programs targeting Medical Procedure. It is currently in Phase 3.
5
Indications
29
Total Trials
5
Active Trials
66
Competitors
Pipeline
Status by Indication[3][1]
Indication
Competition
Competitive Landscape
138 competitors in Periodontitis
#DrugCompanyPhaseTrials
1Peridex
DDexcel Pharma Technologies Ltd.
Phase 3
Acanya
PfizerPhase 3
Curcumin
Merck & Co.Phase 3
Calcium hydroxide
MMansoura University
Phase 3
Docosahexaenoic Acid
MMicelle BioPharma Inc
Phase 2
Calcium Intravenous Infsuion
MMansoura University
Phase 3
Minocycline Hcl
OOraPharma
Phase 3
Metapex
AAga Khan University
Phase 3
Boswellia
MMansoura University
Phase 3
Leddermix
MMansoura University
Phase 3
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Clinical
Trials by Indication[1]
Calcium Hydroxide5 trials
Influence of Calcium Hydroxide Chlorhexidine Combination vs. Calcium Hydroxide as an Intra Canal Medicaments in Retreatment Cases
Unknown status·—·Phase 1·NCT03209115·24 enrolled
Clinical and Radiographic Evaluation of Nano Silver Fluoride Versus Calcium Hydroxide in Indirect Pulp Treatment
Completed·—·N/A·NCT04005872·40 enrolled
Effect of Using Nanochitosan Versus Calcium Hydroxide as Disinfectant on Pain and Apical Bone Healing
Unknown status·—·N/A·NCT03724266·60 enrolled
Show 2 more trials
Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication
Recruiting·—·Phase 2/3·NCT06196515·54 enrolled
Indirect Pulp Treatment of Young Permanent Molars Using Photo-Activated Oral Disinfection Versus Calcium Hydroxide
Completed·—·N/A·NCT03631277·32 enrolled
Intracanal Medicament4 trials
The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament
Recruiting·—·Phase 2/3·NCT06207253·48 enrolled
Show 1 more trial
Post Operative Pain3 trials
Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
Completed·—·N/A·NCT04983524·46 enrolled
Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8
Completed·—·N/A·NCT05525013·30 enrolled
Effect of Bromelain Versus Calcium Hydroxide as an Intracanal Medication on the Intensity of Postoperative Pain and Bacterial Load Reduction in Necrotic Single Rooted Lower Premolars
Unknown status·—·Phase 1·NCT05687760·30 enrolled
Periodontitis2 trials
Treatment2 trials
Effect of Calcium Silicate-Based Root Canal Medicament After Retreatment
Completed·—·N/A·NCT06779370·60 enrolled
12 more indications
Indirect Pulp Cap2 trials
Clinical And Radiographic Evaluation Of Premixed Bio-ceramic MTA In Indirect Pulp Capping Of Young Permanent Molars
Unknown status·—·Phase 3·NCT05928858·40 enrolled
Clinical and Radiographic Evaluation of Indirect Pulp Capping in Primary and Permanent Teeth With Different Materials
Completed·—·N/A·NCT03606681·300 enrolled
Mineral Trioxide Aggregate1 trial
Inflammatory Mediators1 trial
Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators
Completed·—·N/A·NCT06307678·60 enrolled
Primary Teeth1 trial
Indirect Pulp Treatment in Primary Teeth
Unknown status·—·N/A·NCT04763057·88 enrolled
Inflammatory Cytokines1 trial
ESS1 trial
Adult1 trial
ALS1 trial
Effect Of Different Lining Materials in Stepwise Excavation
Unknown status·—·Phase 2·NCT01730287·100 enrolled
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Calcium hydroxide. EMBL-EBI & Wellcome Sanger Institute.
- [4]
Details
Drug Info
Quick Facts
- Modality
- Small molecule[2]
- Highest Phase
- Phase 3[1]
- Company
- MMansoura University