Oxycodone-Acetaminophen

ApprovedSmall molecule

MMontefiore Medical Center

Oxycodone-Acetaminophen is one of 61 small molecule programs targeting Low back pain. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Low Back PainActive, not recruiting

Post Operative PainRecruiting

Low Back PainApproved

Active, not recruiting

Post Operative PainPreclinical

Recruiting

Competition

Competitive Landscape

237 competitors in Low Back Pain

#DrugCompanyPhaseTrials

Sympazan

Lundbeck

Phase 3

1 2

Arcoxia

Novartis

Phase 3

1 3

Tofranil

Sanofi

Phase 3

1 4

Pred Forte

Suboxone

4 6

Keterol

PPamukkale University

Phase 3

3 7

Tylenol

KKenvue Brands

Phase 3

3 8

Circadin

NNeurim Pharmaceuticals Ltd.

Phase 3

1 9

Botox

RRevance Therapeutics, Inc.

Phase 3

1 10

Voltaren

CCerimon Pharmaceuticals

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

PreclinicalRecruiting

Post Operative Pain

NCT07699601

Phase 3Recruiting

Pain Control

NCT03823534

Clinical

Trials by Indication[1]

Postoperative Pain Control2 trials

Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery

Completed·UUniversity Hospitals Cleveland Medical Center·Phase 3·NCT04246554·49 enrolled

Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery

Completed·UUniversity Hospitals Cleveland Medical Center·Phase 3·NCT04246541·48 enrolled

Effectiveness1 trial

Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions

Unknown status·TThe Methodist Hospital Research Institute·Phase 1·NCT04112550·150 enrolled

Prostatectomy1 trial

Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy

Withdrawn·WWake Forest University Health Sciences·Phase 2/3·NCT04939987

Pain Control1 trial

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Recruiting·SSt. Louis University·Phase 3·NCT03823534·60 enrolled

Opioid Analgesia1 trial

Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.

Completed·MMontefiore Medical Center·Phase 3·NCT03584373·119 enrolled

2 more indications

Low back pain1 trial

A Randomized Study of Three Medication Regimens for Acute Low Back Pain

Completed·MMontefiore Medical Center·Phase 4·NCT01587274·323 enrolled

Post Operative Pain1 trial

A Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled Parallel-Group Phase II/III Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablets for Postoperative Analgesia in Orthopedic Surgery

Recruiting·SShanghai Huilun Pharmaceutical Co., Ltd.·Preclinical·NCT07699601·330 enrolled

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for Oxycodone-Acetaminophen. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Oxycodone-Acetaminophen compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Oxycodone-Acetaminophen. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Montefiore Medical Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: MMontefiore Medical Center

Oxycodone-Acetaminophen

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Trials by Indication[1]

Postoperative Pain Control2 trials

Effectiveness1 trial

Prostatectomy1 trial

Pain Control1 trial

Opioid Analgesia1 trial

Low back pain1 trial

Post Operative Pain1 trial

References

Drug Info

Quick Facts

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