Keterol

(Dexketoprofen)

ApprovedSmall molecule

Dexketoprofen is used to relieve moderate pain and reduce fever. It works similarly to ibuprofen by reducing inflammation and pain signals in the body.[2] Keterol is currently approved and in use across 13 indications[4].[1]

Keterol is one of 247 small molecule programs targeting Low back pain. It is currently in Approved.

Indications

Total Trials

Active Trials

246

Competitors

Pipeline

Status by Indication[4][1]

Indication

Low Back PainActive, not recruiting

Rheumatic DiseaseUnknown

Bone FractureActive, not recruiting

DysmenorrheaActive, not recruiting

ArthralgiaUnknown

Renal ColicActive, not recruiting

MigraineActive, not recruiting

Cesarean SectionActive, not recruiting

MyalgiaUnknown

SprainActive, not recruiting

Low Back PainPhase 3

Active, not recruiting

Rheumatic DiseasePreclinical

Unknown

Bone FractureApproved

Active, not recruiting

DysmenorrheaApproved

Active, not recruiting

ArthralgiaPreclinical

Unknown

Renal ColicApproved

Active, not recruiting

MigraineApproved

Active, not recruiting

Cesarean SectionPreclinical

Active, not recruiting

MyalgiaPreclinical

Unknown

SprainPhase 3

Active, not recruiting

Competition

Competitive Landscape

357 competitors in Migraine

#DrugCompanyPhaseTrials

Keterol

PPamukkale University

Approved

1 2

Aimovig

Amgen

Preclinical

33 3

Vyepti

Lundbeck

Preclinical

12 4

Bayer Aspirin

Bayer

Preclinical

2 5

Savella

AbbVie

Preclinical

2 6

Cymbalta

Alnylam Pharmaceuticals

Preclinical

1 7

Botox

RRevance Therapeutics, Inc.

Preclinical

9 8

Adempas

Bayer

Preclinical

1 9

Cervidil

Pfizer

Preclinical

1 10

Viagra

VViatris Specialty LLC

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Low back pain3 trials

IV Paracetamol, Dexketoprofen or Morphine for the Treatment of Low Back Pain

Completed·PPamukkale University·Phase 4·NCT01422291·120 enrolled

The Efficacy of Dexketoprofen And Methylprednisolone in the Acute Low Back Pain

Completed·AAli Gur·Phase 4·NCT06932367·150 enrolled

Paracetamol, Dexketoprofen and Ibuprofen In Non-Traumatic Acute Low Back Pain

Completed·PPamukkale University·Phase 4·NCT04609254·210 enrolled

Dysmenorrhea2 trials

IV Paracetamol Versus IV Dexketoprofen in Dysmenorrhea

Unknown status·—·Phase 4·NCT02373514·100 enrolled

IV Magnesium in the Treatment of Acute Dysmenorrhea

Recruiting·HHavva Betül Bacak·N/A·NCT07248540·60 enrolled

Headache2 trials

Intravenous Paracetamol, Dexketoprofen and Ibuprofen in the Treatment of Acute Migraine Attack Headache

Unknown status·PPamukkale University·Phase 4·NCT04372264·210 enrolled

Intravenous Dexketoprofen and Paracetamol in the Treatment of Headache Caused by Acute Migraine Attack

Completed·PPamukkale University·Phase 4·NCT01730326·200 enrolled

Musculoskeletal Pain2 trials

Comparison of Efficacy of Intravenous Paracetamol and Dexketoprofen for Acute Traumatic Musculoskeletal Pain

Completed·PPamukkale University·Phase 4·NCT03428503·200 enrolled

Comparison of Efficacy of Intravenous Paracetamol and Dexketoprofen for Acute Nontraumatic Musculoskeletal Pain

Completed·PPamukkale University·Phase 4·NCT03122314·200 enrolled

Pain Management2 trials

Comparison of Superior Hypogastric Plexus Block and Peritoneal Bupivacaine in Pain Management

Completed·EEnes Celik··NCT06954896·94 enrolled

Enantyum® IV Versus Piroxen® IM in Emergency Pain Management

Recruiting·RRiadh Boukef·Phase 3·NCT06404177·300 enrolled

14 more indications

Intravenous2 trials

Comparison of the Efficacy of Intravenous Dexketoprofen and Paracetamol in the Treatment of Sore Throat

Completed·PPamukkale University·Phase 4·NCT03768882·200 enrolled

Efficacy of Intravenous Dexketoprofen and Tenoxicam on Propofol Associated Injection Pain

Completed·OOrdu University·Phase 4·NCT02285972·118 enrolled

Postoperative Analgesia2 trials

Intravenous Paracetamol Compared Dexketoprofen for Postoperative Analgesia After Septoplasty

Unknown status·—·Phase 3·NCT02602197·2 enrolled

Comparison of Efficacy and Safety of the Postoperative Analgesia Methods

Unknown status·IIstanbul University·Phase 4·NCT02929147·90 enrolled

Migraine1 trial

Ibuprofen in Migraine Patients

Completed·KKecioren Education and Training Hospital·Phase 4·NCT04533568·160 enrolled

Sprain1 trial

Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II

Completed·LLaboratorios Silanes S.A. de C.V.·Phase 3·NCT05001555·174 enrolled

Fasting Conditions1 trial

Comparison of Bioavailability of Dexketoprofen-Vit B vs Dexketoprofen, in Healthy Subjects, Under Fasting Conditions

Completed·LLaboratorios Silanes S.A. de C.V.·Phase 1·NCT05027126·36 enrolled

Prevention1 trial

Effects of Cyclooxygenase (COX) 1-2 Inhibitors on Prevention of Rocuronium Injection Pain

Completed·—·N/A·NCT04582032·68 enrolled

Age1 trial

Dexketoprofen Dosage According to Chronotherapy

Completed·UUniversidad Complutense de Madrid·N/A·NCT05176158·10 enrolled

Renal Colic1 trial

Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum Treatment

Completed·—·Phase 4·NCT03865004·136 enrolled

Hip Arthroplasty1 trial

Dexketoprofen and Etoricoxib in Patients Undergoing Hip Arthroplasty

Completed·KKuopio University Hospital·Phase 4·NCT02568735·24 enrolled

Cesarean Section1 trial

Parecoxib vs. Dexketoprofen for the Management of Pain After Cesarean Section.

Completed·SSaint Thomas Hospital, Panama·N/A·NCT04847024·380 enrolled

Bone Fracture1 trial

Dexketoprofen and Ibuprofen in Long Bone Fractures

Unknown status·—·Phase 4·NCT06060236·100 enrolled

Breast Surgery1 trial

Intercostal Nerves Block in the Midaxillary Line Versus Paravertebral Block for no Reconstructive Breast Surgery

Unknown status·PPaula Diéguez García·Phase 4·NCT02018601·120 enrolled

Hysteroscopy1 trial

Oral Tramadol Versus Oral Dexketoprofen for Reducing Pain During Office Hysteroscopy

Unknown status·—·Phase 3·NCT03585036·210 enrolled

Unspecified1 trial

IV Dexketoprofen vs Placebo in Migranie Attack

Completed·—·Phase 4·NCT02159547·224 enrolled

Sources

References

[1]
ClinicalTrials.gov — 27 trial records for Dexketoprofen. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Keterol drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — Dexketoprofen compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for Dexketoprofen. EMBL-EBI & Wellcome Sanger Institute.
[5]
SEC EDGAR — Pamukkale University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Cyclooxygenase Inhibitor[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: PPamukkale University

Keterol

Status by Indication[4][1]

Competitive Landscape

Trials by Indication[1]

Low back pain3 trials

Dysmenorrhea2 trials

Headache2 trials

Musculoskeletal Pain2 trials

Pain Management2 trials

Intravenous2 trials

Postoperative Analgesia2 trials

Migraine1 trial

Sprain1 trial

Fasting Conditions1 trial

Prevention1 trial

Age1 trial

Renal Colic1 trial

Hip Arthroplasty1 trial

Cesarean Section1 trial

Bone Fracture1 trial

Breast Surgery1 trial

Hysteroscopy1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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