parecoxib sodium

Phase 3Small molecule

Pfizer

parecoxib sodium is one of 54 small molecule programs targeting Hepatocellular Carcinoma. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Hepatocellular CarcinomaActive, not recruiting

PancreatitisNot yet recruiting

Lung NodulesRecruiting

Hepatocellular CarcinomaPreclinical

Active, not recruiting

PancreatitisPhase 2

Not yet recruiting

Lung NodulesPhase 3

Recruiting

Competition

Competitive Landscape

265 competitors in Hepatocellular Carcinoma

#DrugCompanyPhaseTrials

parecoxib sodium

Pfizer

Phase 3

1 2

Ibrance

Pfizer

Preclinical

1 3

Cysteine Hydrochloride

Novartis

Preclinical

1 4

Sovaldi

Gilead

Preclinical

1 5

Hepsera

Doptelet

1 7

Miraclid

TTechpool Bio-Pharma Co., Ltd.

Preclinical

1 8

Vermox

WWim Janssens

Preclinical

1 9

Valemetostat

Bristol-Myers Squibb

Preclinical

1 10

Alcohol

Astellas

Preclinical

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Phase 2Not yet recruiting

Pancreatitis

NCT06623513

Q2 2028

ApprovedRecruiting

Lung Nodules

NCT07675473

Clinical

Trials by Indication[1]

Efficacy and Safety2 trials

Efficacy And Safety Of Parecoxib IV/IM 40 Mg Vs Placebo Following Sub Muscular Breast Augmentation

Withdrawn· Pfizer logo

Pfizer·Phase 4·NCT00435747

Efficacy and Safety of Parecoxib on Morphine Patient-controlled Epidural Analgesia (PCEA) After Gynecologic Surgery

Completed·LLiu Weifeng·N/A·NCT01566669·294 enrolled

Hepatocellular Carcinoma1 trial

Preventive Effects of Parecoxib on Postoperative Complications in Hepatocellular Carcinoma Patients Undergoing Hepatic Transcatheter Arterial Chemoembolization

Completed·SSun Yat-sen University··NCT02552745·200 enrolled

Postoperative Pain Management1 trial

Role of Parecoxib Sodium for Postoperative Pain Management in Open Hepatectomy

Unknown status·PPeking Union Medical College Hospital·Phase 4·NCT02204878·100 enrolled

Pain Control1 trial

Parecoxib Versus Celecoxib Versus Oxycodone in Pain Control for Transcatheter Chemoembolization Procedure

Completed·SSun Yat-sen University·Phase 3·NCT03059238·213 enrolled

Pancreatitis1 trial

Efficacy and Safety of Parecoxib vs. Indomethacin in Preventing Post-ERCP Pancreatitis

Not yet recruiting·SShanghai General Hospital, Shanghai Jiao Tong University School of Medicine·Phase 2·NCT06623513·100 enrolled

4 more indications

Shivering1 trial

Effect of Parecoxib Sodium and Flurbiprofen Injection on Postoperative Shivering

Completed·GGuangxi Medical University·Phase 4·NCT02569905·166 enrolled

Post Operative Pain1 trial

The Correlation of COX-2 Expression in Human Polymorphonuclear Leukocytes/Macrophages (PMNL/MP) and Postoperative Pain

Completed·XXianwei Zhang·Phase 4·NCT01186159·90 enrolled

Total Knee Arthroplasty1 trial

Parecoxib for Pain Management After Total Knee Arthroplasty and Total Hip Arthroplasty

Completed·PPeking Union Medical College Hospital·Phase 4·NCT02272660·74 enrolled

Lung Nodules1 trial

Application of Pre-Emptive Analgesia With Parecoxib Sodium in CT-Guided Hook Wire Localization of Lung Nodules Before Video-Assisted Thoracoscopic Surgery and Exploration of the Optimal Clinical Dosing Window: A Single-Center, Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Recruiting·LLong Jiang·Approved·NCT07675473·150 enrolled

Sources

References

[1]
ClinicalTrials.gov — 10 trial records for parecoxib sodium. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — parecoxib sodium compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for parecoxib sodium. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Pfizer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: Pfizer

parecoxib sodium

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2026

Q2 2028

Trials by Indication[1]

Efficacy and Safety2 trials

Hepatocellular Carcinoma1 trial

Postoperative Pain Management1 trial

Pain Control1 trial

Pancreatitis1 trial

Shivering1 trial

Post Operative Pain1 trial

Total Knee Arthroplasty1 trial

Lung Nodules1 trial

References

Drug Info

Quick Facts

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