Spinal Morphine

Phase 3Small molecule

MMahidol University

Spinal Morphine is one of 11 small molecule programs targeting Erector Spinae Plane Block. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Erector Spinae Plane BlockRecruiting

Postoperative Pain ControlUnknown status

Erector Spinae Plane BlockPhase 3

Recruiting

Postoperative Pain ControlPreclinical

Unknown status

Competition

Competitive Landscape

10 competitors in Erector Spinae Plane Block

#DrugCompanyPhaseTrials

Decadron

AAspen Global Incorporated

Approved

5 2

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Approved

5 3

Marcaine

IInnocoll

Phase 3

13 4

Spinal Morphine

MMahidol University

Phase 3

1 5

General Anesthetic

IInstitutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu

Preclinical

2 6

Opioids

SSahlgrenska University Hospital

Preclinical

1 7

Bupivacaine-Epinephrine

UUniversity of Aarhus

Preclinical

1 8

Dexamethasone and Dexmedetomidine

HHuazhong University of Science and Technology

Preclinical

1 9

Morphine PCA Pump

MMedical University of Warsaw

Preclinical

2 10

Anesthetics, Local

HHelsinki University Central Hospital

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Cesarean Delivery1 trial

Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia

Completed·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 4·NCT03592992·126 enrolled

Postoperative Pain Control1 trial

Postoperative Pain Control After Kidney Surgery : a Comparison of Intrathecal Morphine Plus PCA and PCA Only

Unknown status·KKhon Kaen University·N/A·NCT00199316·80 enrolled

Treatment1 trial

0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.

Unknown status·MMahidol University·Phase 4·NCT01979354·40 enrolled

Erector Spinae Plane Block1 trial

Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

Recruiting·UUniversity of California, San Diego·Phase 4·NCT04849455·70 enrolled

Analgesia1 trial

Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 mg for Post Lobectomy Analgesia

Completed·MMahidol University·Phase 4·NCT01236495·40 enrolled

1 more indication

Hysterectomy1 trial

0.05 Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy

Unknown status·MMahidol University·Phase 4·NCT01079754·72 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Spinal Morphine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Spinal Morphine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Spinal Morphine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Mahidol University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: MMahidol University

Spinal Morphine

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Cesarean Delivery1 trial

Postoperative Pain Control1 trial

Treatment1 trial

Erector Spinae Plane Block1 trial

Analgesia1 trial

Hysterectomy1 trial

References

Drug Info

Quick Facts

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