General anesthetic

PreclinicalSmall molecule

IInstitutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu

General anesthetic is one of 164 small molecule programs targeting Neurotoxicity. It is currently in Preclinical.

Indications

Total Trials

Active Trials

163

Competitors

Pipeline

Status by Indication[3][1]

Indication

NeurotoxicityActive, not recruiting

DeliriumActive, not recruiting

CognitionActive, not recruiting

Erector Spinae Plane BlockCompleted

General AnesthesiaCompleted

Cesarean SectionActive, not recruiting

NeurotoxicityPreclinical

Active, not recruiting

DeliriumPreclinical

Active, not recruiting

CognitionPreclinical

Active, not recruiting

Erector Spinae Plane BlockPreclinical

Completed

General AnesthesiaPreclinical

Completed

Cesarean SectionPreclinical

Active, not recruiting

Competition

Competitive Landscape

85 competitors in Cognition

#DrugCompanyPhaseTrials

Duragesic

CCephalon

Approved

1 2

Accutane

CConrado Roberto Hoffmann Filho

Approved

1 3

Xarelto

WWim Janssens

Approved

1 4

Neurontin

VViatris Specialty LLC

Approved

1 5

Ambien

PPurdue Pharma LP

Approved

1 6

Osmitrol

BB. Braun Medical Inc.

Namenda

3 8

Nuplazid

AACADIA Pharmaceuticals Inc.

Phase 2

1 9

Remimazolam Tosilate

FFujian Shengdi Pharmaceutical Co., Ltd.

Phase 3

1 10

Psilocybin

COMPASS Pathways

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2027

N/ANot yet recruiting

Cesarean Section

NCT07334418

Clinical

Trials by Indication[1]

General Anesthesia2 trials

General Anesthesia With or Without Local Ear Block in Middle Ear Surgeries

Completed·AAbd-Elazeem Abd-Elhameed Elbakry·N/A·NCT03569046·80 enrolled

Physiological Effects of Lung Recruitment During General Anesthesia and Low-tidal Volume Ventilation

Completed·—·N/A·NCT03083457·30 enrolled

Erector Spinae Plane Block2 trials

Erector Spinae Plane Block Versus Paravertebral Block

Completed·UUniversity of Alberta·N/A·NCT03471442·48 enrolled

NOL-Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block

Completed·IInstitutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu·N/A·NCT06070701·40 enrolled

Neurotoxicity1 trial

Anesthetic Neurotoxicity: the Association Between General Anesthesia and the Level of Plasma Neurofilament Light

Unknown status·CCardiocentro Ticino··NCT04164329·120 enrolled

Complication1 trial

Impact of Functional Status on 30-day Resource Utilization and Organ System Complications Following Bariatric Surgery

Completed·UUniversity of Virginia··NCT05917691·65,627 enrolled

Patient Satisfaction1 trial

Patient Satisfaction After Surgery for Otosclerosis Under Local ou General Anesthesia

Completed·RRennes University Hospital··NCT03888079·103 enrolled

10 more indications

Delirium1 trial

Characterisation of Gut Microbiota in Patients Undergoing Gastrointestinal Surgery With Postoperative Delirium (GIM-POD)

Unknown status·—··NCT04316910·30 enrolled

Total Knee Arthroplasty1 trial

Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia

Unknown status·MMeir Medical Center·Phase 4·NCT03176758·60 enrolled

Minimal Invasive Cardiac Surgery1 trial

Erector Spinae Plane Block in Minimal Invasive Cardiac Surgery

Unknown status·—·N/A·NCT03825068·20 enrolled

Magnesium Sulfate1 trial

the Effect of Dexmedetomidine and Magnesium Sulfate in Open Resection of Pheochromocytoma

Completed·NNational Cancer Institute, Egypt·Phase 2·NCT04320589·30 enrolled

MPR1 trial

GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries

Enrolling by invitation·HHospital for Special Surgery, New York·Phase 3·NCT05444751·142 enrolled

Not yet recruiting·UUniversity of Pennsylvania·N/A·NCT07334418·600 enrolled

Breast1 trial

MAC vs TIVA Ambulatory Breast Augmentation

Completed·—·Phase 3·NCT03764267·80 enrolled

Post Operative Pain1 trial

Role of TAP and RS Block in Reduction of Postoperative Pain for Gynecological Surgical Laparoscopic Procedures

Unknown status·—·Phase 2·NCT03536741·70 enrolled

Sources

References

[1]
ClinicalTrials.gov — 17 trial records for General anesthetic. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — General anesthetic compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for General anesthetic. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: IInstitutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu

General anesthetic

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2027

Trials by Indication[1]

General Anesthesia2 trials

Erector Spinae Plane Block2 trials

Neurotoxicity1 trial

Complication1 trial

Patient Satisfaction1 trial

Delirium1 trial

Total Knee Arthroplasty1 trial

Minimal Invasive Cardiac Surgery1 trial

Magnesium Sulfate1 trial

MPR1 trial

Open Heart Surgery1 trial

Cognition1 trial

Cesarean Section1 trial

Breast1 trial

Post Operative Pain1 trial

References

Drug Info

Quick Facts

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