Trabectedin is used to treat certain types of cancer, particularly soft tissue sarcoma and ovarian cancer. It works by damaging cancer cell DNA to stop the cancer from growing.[2] Yondelis is currently approved and in use across 10 indications[4].[1]
Yondelis is one of 114 small molecule programs targeting Soft Tissue Neoplasm. It is currently in Approved.
Indications
Total Trials
Active Trials
Competitors
FDA Applications
NDA/BLA/ANDA regulatory filings
Patents
Pipeline
Competition
60 competitors in Soft Tissue Sarcoma
Votrient
Yondelis
Adriamycin
Adriamycin
Lynparza
Idamycin
Ifex
Farydak
Treanda
Neulasta
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Clinical
Regulatory
Oct 23, 2015
YONDELIS
NDA NDA207953
Jul 20, 2016
YONDELIS
NDA NDA207953
May 18, 2017
YONDELIS
NDA NDA207953
Jun 29, 2018
YONDELIS
NDA NDA207953
Dec 28, 2018
YONDELIS
NDA NDA207953
Jun 3, 2020
YONDELIS
NDA NDA207953
Dec 23, 2025
YONDELIS
NDA NDA207953
May 1, 2026
EVDI
NDA NDA220837
Sources
Details
Patent Cliff
Jan 7, 2028
Earliest patent expiration — generic entry possible after this date