Ampicillin-Sulbactam

ApprovedSmall molecule

Pfizer

Ampicillin-Sulbactam is one of 109 small molecule programs targeting Bacterial Pneumonia. It is currently in Approved.

Indications

Total Trials

Active Trials

108

Competitors

Pipeline

Status by Indication[3][1]

Indication

Bacterial PneumoniaActive, not recruiting

Skin InfectionActive, not recruiting

Cesarean SectionActive, not recruiting

Bacterial PneumoniaPhase 3

Active, not recruiting

Skin InfectionApproved

Active, not recruiting

Cesarean SectionApproved

Active, not recruiting

Competition

Competitive Landscape

230 competitors in Cesarean Section

#DrugCompanyPhaseTrials

Ampicillin-Sulbactam

Pfizer

Approved

1 2

Marcaine

IInnocoll

Preclinical

21 3

Pitocin

RRetrophin

Preclinical

16 4

Naropin

FFresenius Kabi Oncology Ltd.

Preclinical

12 5

Neo-Synephrine

EExela Pharma Sciences, LLC.

Preclinical

11 6

Dynastat

Pfizer

Preclinical

1 7

Proamatine

Takeda

Preclinical

1 8

Duragesic

CCephalon

Preclinical

6 9

Xylocaine

MMEDRx USA, Inc.

Preclinical

4 10

Versed

CConrado Roberto Hoffmann Filho

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Post-ApprovalRecruiting

Ampicillin

NCT05922124

Q1 2027

N/ARecruiting

Surgery

NCT06336213

Q1 2028

Phase 3Not yet recruiting

Bacterial Pneumonia

NCT07326540

Clinical

Trials by Indication[1]

Ampicillin2 trials

T.E.A. Study Three Days Ertapenem Versus Three Days Ampicillin- Sulbactam

Completed·UUniversity of Bologna·Phase 4·NCT00630513·142 enrolled

Cefiderocol and Ampicillin-sulbactam vs. Colistin +/- Meropenem for Carbapenem Resistant A. Baumannii

Recruiting·RRambam Health Care Campus·Phase 4·NCT05922124·734 enrolled

Laparoscopic Cholecystectomy1 trial

Antibiotic Prophylaxis in Laparoscopic Cholecystectomy

Terminated·UUniversity of Roma La Sapienza·Phase 4·NCT01888822·138 enrolled

Bacterial Pneumonia1 trial

Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex

Not yet recruiting·BBioVersys AG·Phase 3·NCT07326540·248 enrolled

Skin Infection1 trial

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

Completed· Pfizer logo

Pfizer·Phase 4·NCT00368537·550 enrolled

Surgical Site Infections1 trial

Cefepime and Unictam on Preventing Post-Cesarean Surgical Site Infections

Unknown status·—·Phase 3·NCT06048692·213 enrolled

3 more indications

Surgery1 trial

Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients

Recruiting·PPetrovsky National Research Centre of Surgery·N/A·NCT06336213·50 enrolled

Renal Replacement Therapy1 trial

Concentration of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid in the Blood During Renal Replacement Therapy in Longterm Renal Replacement Therapy Patients

Completed·MMedical University of Vienna·Phase 3·NCT02007603·16 enrolled

Cesarean Section1 trial

Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section

Completed·—·Phase 4·NCT01138852·176 enrolled

Sources

References

[1]
ClinicalTrials.gov — 9 trial records for Ampicillin-Sulbactam. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Ampicillin-Sulbactam compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Ampicillin-Sulbactam. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Pfizer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Pfizer

Ampicillin-Sulbactam

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2026

Q1 2027

Q1 2028

Trials by Indication[1]

Ampicillin2 trials

Laparoscopic Cholecystectomy1 trial

Bacterial Pneumonia1 trial

Skin Infection1 trial

Surgical Site Infections1 trial

Surgery1 trial

Renal Replacement Therapy1 trial

Cesarean Section1 trial

References

Drug Info

Quick Facts

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