Carnitor

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Heart FailureRheumatoid ArthritisChronic Kidney DiseaseAsthmaAcute Lymphoblastic LeukemiaMultiple SclerosisHIV InfectionAnemiaSeptic ShockPolycystic Ovary SyndromeSpinal Cord InjuryHypotensionInfertilityEncephalopathyNon-Alcoholic Fatty Liver DiseaseAIDSGastrointestinal Stromal TumorCytomegalovirus InfectionPyelonephritisGlucose IntoleranceProximal Spinal Muscular AtrophyMuscle WeaknessAzoospermiaHyperthyroidismPostpoliomyelitis SyndromeSpinal Muscular Atrophy, Type 1Ventricular Septal Defect

198 competitors in Heart Failure

#DrugCompanyPhaseTrials

1

Carnitor

LLeadiant Biosciences, Inc.

Approved

22

Bayer Aspirin

Bayer

Preclinical

23

Brethine

Sanofi

Preclinical

14

Medrol

Pfizer

Preclinical

15

Amidate

Pfizer

Preclinical

16

Activase

Roche

Preclinical

—7

Zemplar

AbbVie

Preclinical

—8

Adriamycin

Pfizer

Preclinical

—9

Savaysa

Daiichi Sankyo

Preclinical

—10

Xifaxan

SSalix

Preclinical

2Show 31 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Effectiveness5 trials

The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

Completed·Gilead·Phase 2·NCT00002379·100 enrolled

Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations

Completed·Gilead·N/A·NCT00002398

Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected Children

Unknown status·Gilead·Phase 2·NCT00002219·36 enrolled

Show 2 more trials

The Effectiveness of Nelfinavir and Efavirenz, Used Alone or Together, Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00001087·300 enrolled

The Safety and Effectiveness of Adefovir Dipivoxil in the Treatment of HIV-Infected Patients

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 3·NCT00001082·505 enrolled

Drug2 trials

A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000892·300 enrolled

A Study on Amprenavir in Combination With Other Anti-HIV Drugs in HIV-Positive Patients

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00000912·475 enrolled

Heart Failure2 trials

The Clinical Study of the Efficacy and Safety of L-Carnitine Injection in Treatment of Heart Failure

Completed·LLee's Pharmaceutical Limited·Phase 2/3·NCT01580553·268 enrolled

Oral Carnitine in Heart Failure Patients

Not yet recruiting·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 1·NCT07201714·20 enrolled

Fatigue1 trial

Effect of Levocarnitine Supplementation for the Management of Fatigue in Levothyroxine-Treated Hypothyroid Patients

Unknown status·—·N/A·NCT03372772·90 enrolled

Safety and Efficacy1 trial

A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient

Completed·Gilead·Phase 2·NCT00002184·120 enrolled

7 more indications

HIV1 trial

Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir

Completed·Merck & Co.·Phase 3·NCT00002220·120 enrolled

Peripheral Neuropathy1 trial

A Randomized Controlled Trial to Assess the Effect of L-carnitine in Patients With Diabetic Peripheral Neuropathy to Relief Pain and Symptom Improvement

Unknown status·—·Phase 2·NCT04145245·104 enrolled

Sjogren's Syndrome1 trial

Levocarnitine for Dry Eye in Sjogren's Syndrome

Completed·VVanderbilt University Medical Center·Phase 2·NCT03953703·15 enrolled

Treatment1 trial

Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination With Nucleoside Analogs: A Rollover Study for ACTG 320

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00000885·440 enrolled

Anemia1 trial

Levocarnitine for Reducing ESA Requirements in Hemodialysis Patients With Renal Anemia

Not yet recruiting·—·Phase 4·NCT07160452·94 enrolled

Dialysis Patients1 trial

Effects of L-carnitine Therapy on the Heart of Maintenance Hemodialysis Patients

Completed·TThe First Affiliated Hospital of Zhejiang Chinese Medical University·Phase 4·NCT05673239·1,008 enrolled

Acute Lymphoblastic Leukemia1 trial

Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia

Recruiting·—·Phase 1·NCT05501899·20 enrolled

Regulatory

FDA Approval Timeline[4]

Details

Drug Info

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