Dynastat
(Parecoxib)ApprovedSmall molecule
PfizerParecoxib is used to relieve moderate to severe pain after surgery. It works quickly to reduce pain and is often given as an injection in hospitals after operations.[2] Dynastat is currently approved and in use across 11 indications[4].[1]
Dynastat is one of 282 small molecule programs targeting Insulin resistance. It is currently in Approved.
11
Indications
26
Total Trials
5
Active Trials
281
Competitors
Pipeline
Status by Indication[4][1]
Indication
Competition
Competitive Landscape
275 competitors in Total Knee Arthroplasty
#DrugCompanyPhaseTrials
1Dynastat
PfizerApproved
Cymbalta
Alnylam PharmaceuticalsPreclinical
Lyrica
PPfizer's Upjohn has merged with Mylan to form Viatris Inc.
Preclinical
Xarelto
WWim Janssens
Preclinical
Precedex
MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Preclinical
Sufenta
LLeaf Vertical Inc.
Preclinical
EXPAREL
Pacira Pharmaceuticals, IncPreclinical
Nucynta
CCollegium Pharmaceutical, Inc.
Preclinical
Epsom Salt
FFresenius Kabi Oncology Ltd.
Preclinical
Zanaflex
LLegacy Health System
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Shoulder pain3 trials
Postoperative Analgesia3 trials
Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy
Not yet recruiting·TThe Fourth Affiliated Hospital of Zhejiang University School of Medicine·N/A·NCT06304181·90 enrolled
Renal Colic3 trials
Fasting Conditions1 trial
Subarachnoid Hemorrhage1 trial
Evaluation of the Safety and Efficacy of Parecoxib in Patients With Subarachnoid Hemorrhage
Not yet recruiting·SSt. Anne's University Hospital Brno, Czech Republic·Phase 2·NCT06579274·112 enrolled
15 more indications
Rib Fracture1 trial
Early Parecoxib Usage to Decreases Narcotic Requirement and Length of Stay After Traumatic Rib Fracture
Terminated·—·Phase 3·NCT02749409·17 enrolled
Video-Assisted Thoracoscopic Surgery1 trial
Post Operative Sore Throat1 trial
Effect of Intravenous Dynastat on Postoperative Sore Throat
Unknown status·—·Phase 2·NCT03915561·140 enrolled
Lidocaine1 trial
Insulin resistance1 trial
Post Operative Pain1 trial
Preemptive Analgesic Efficacy of Parecoxib for Reducing Postoperative Pain in Gynecological Surgery
Completed·DDepartment of Medical Services Ministry of Public Health of Thailand·Phase 4·NCT06140238·178 enrolled
Cesarean Section1 trial
Analgesic1 trial
Total Knee Arthroplasty1 trial
Combination of Continuous Femoral Block and Intravenous Parecoxib For Postoperative Analgesia After Total Knee Arthroplasty
Completed·—·Phase 2/3·NCT02185924·90 enrolled
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Dynastat drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Parecoxib. EMBL-EBI & Wellcome Sanger Institute.
- [5]