Dynastat
(Parecoxib)Phase 3Small molecule
PfizerParecoxib is used to relieve moderate to severe pain after surgery. It works quickly to reduce pain and is often given as an injection in hospitals after operations.[1] Dynastat is currently being investigated across 8 indications[3], with its most advanced program in Phase 3.[1]
Dynastat is one of 146 small molecule programs targeting Causalgia. It is currently in Phase 3.
8
Indications
26
Total Trials
5
Active Trials
145
Competitors
Pipeline
Status by Indication[3][1]
Indication
Competition
Competitive Landscape
83 competitors in Cesarean Section
#DrugCompanyPhaseTrials
1Dynastat
PfizerPhase 3
Fentanyl-Morphine
SSeoul National University Hospital
Phase 3
Ondansetron, Dexamethasone
KKing Khaled Eye Specialist Hospital
Phase 3
Acetaminophen/ibuprofen
SSeoul National University Hospital
Phase 3
Morphine - .
RRambam Health Care Campus
Phase 3
Sebacoyl Dinalbuphine Ester
LLumosa Therapeutics Co., Ltd.
Phase 3
Proamatine
TakedaPreclinical
Duragesic
CCephalon
Preclinical
Versed
CConrado Roberto Hoffmann Filho
Preclinical
Catapres
Boehringer IngelheimPreclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Renal Colic3 trials
Shoulder pain3 trials
Postoperative Analgesia3 trials
Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy
Not yet recruiting·TThe Fourth Affiliated Hospital of Zhejiang University School of Medicine·N/A·NCT06304181·90 enrolled
15 more indications
Total Knee Arthroplasty1 trial
Combination of Continuous Femoral Block and Intravenous Parecoxib For Postoperative Analgesia After Total Knee Arthroplasty
Completed·—·Phase 2/3·NCT02185924·90 enrolled
Fasting Conditions1 trial
Rib Fracture1 trial
Early Parecoxib Usage to Decreases Narcotic Requirement and Length of Stay After Traumatic Rib Fracture
Terminated·—·Phase 3·NCT02749409·17 enrolled
Lidocaine1 trial
Post Operative Pain1 trial
Preemptive Analgesic Efficacy of Parecoxib for Reducing Postoperative Pain in Gynecological Surgery
Completed·DDepartment of Medical Services Ministry of Public Health of Thailand·Phase 4·NCT06140238·178 enrolled
Video-Assisted Thoracoscopic Surgery1 trial
Insulin resistance1 trial
Analgesic1 trial
Post Operative Sore Throat1 trial
Effect of Intravenous Dynastat on Postoperative Sore Throat
Unknown status·—·Phase 2·NCT03915561·140 enrolled
Patient-Controlled Analgesia1 trial
Neurological Complication1 trial
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Parecoxib. EMBL-EBI & Wellcome Sanger Institute.
- [4]