Ropivicaine

ApprovedSmall molecule

TThomas Jefferson University

Ropivicaine is one of 83 small molecule programs targeting Hernia. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Total Knee ArthroplastyActive, not recruiting

Femur FractureActive, not recruiting

Cesarean SectionActive, not recruiting

Total Knee ArthroplastyApproved

Active, not recruiting

Femur FracturePhase 2

Active, not recruiting

Cesarean SectionPreclinical

Active, not recruiting

Competition

Competitive Landscape

275 competitors in Total Knee Arthroplasty

#DrugCompanyPhaseTrials

Ropivicaine

TThomas Jefferson University

Approved

2 2

Cymbalta

Alnylam Pharmaceuticals

Preclinical

5 3

Lyrica

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

7 4

Xarelto

WWim Janssens

Preclinical

5 5

Sufenta

LLeaf Vertical Inc.

Preclinical

3 6

EXPAREL

Pacira Pharmaceuticals, Inc

Preclinical

7 7

Xylocaine

MMEDRx USA, Inc.

Preclinical

2 8

Nucynta

CCollegium Pharmaceutical, Inc.

Preclinical

2 9

Epsom Salt

FFresenius Kabi Oncology Ltd.

Preclinical

1 10

Zanaflex

LLegacy Health System

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Post-ApprovalActive, not recruiting

Shoulder Arthroplasty

NCT05488847

Clinical

Trials by Indication[1]

Total Knee Arthroplasty2 trials

Implementation of a Pain Management Protocol for Total Knee Arthroplasty

Completed·HHealth Sciences North Research Institute·Phase 4·NCT02474654·220 enrolled

A Trial Comparing Adductor Canal Catheter and Intraarticular Catheter Following Primary Total Knee Arthroplasty

Unknown status·TThomas Jefferson University·Phase 4·NCT02497911·110 enrolled

Hernia1 trial

Local Anaesthetic Following Hernia Repair

Terminated·RRoyal Hobart Hospital·Phase 1·NCT00471692·12 enrolled

Femur Fracture1 trial

Femoral Nerve Block for Femur Fracture Repair in Pediatrics

Terminated·NNationwide Children's Hospital·Phase 2·NCT01759407·19 enrolled

Cesarean Section1 trial

Trans-Abdominis Plane Block Efficacy for Post-Cesarean Section Pain

Withdrawn·VVanderbilt University·N/A·NCT00945620

Postoperative Pain Control1 trial

Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery

Completed·IIWK Health Centre·Phase 4·NCT01261637·86 enrolled

6 more indications

Local Anesthetic1 trial

Ultrasound Guided Local Anesthetic Block: Thoracolumbar Interfascial Plane

Completed·MMedical University of South Carolina·Phase 1·NCT02297191·10 enrolled

Pain Control1 trial

Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps

Completed·IIcahn School of Medicine at Mount Sinai·Phase 2·NCT03349034·24 enrolled

Shoulder Arthroplasty1 trial

Opioid-Free Pain Protocol After Shoulder Arthroplasty

Active, not recruiting·HHenry Ford Health System·Phase 4·NCT05488847·83 enrolled

Ropivacaine1 trial

Labour Epidural Top-up With Warmed Ropivacaine

Unknown status·GGuy's and St Thomas' NHS Foundation Trust·N/A·NCT02838329·90 enrolled

Nerve Block1 trial

Continuous Femoral and Tibial Nerve Blocks in TKA Patients

Terminated·TTexas Tech University Health Sciences Center, El Paso·Phase 1·NCT01680692·2 enrolled

Unspecified1 trial

Hip Scope Fascia-iliaca (FI) Block Study

Completed·TThe Hawkins Foundation·Phase 4·NCT02365961·84 enrolled

Sources

References

[1]
ClinicalTrials.gov — 12 trial records for Ropivicaine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Ropivicaine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Ropivicaine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Thomas Jefferson University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: TThomas Jefferson University

Ropivicaine

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2026

Trials by Indication[1]

Total Knee Arthroplasty2 trials

Hernia1 trial

Femur Fracture1 trial

Cesarean Section1 trial

Postoperative Pain Control1 trial

Local Anesthetic1 trial

Pain Control1 trial

Shoulder Arthroplasty1 trial

Ropivacaine1 trial

Nerve Block1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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