Sodium Hyaluronate

ApprovedSmall molecule

Sanofi

Sodium Hyaluronate is one of 293 small molecule programs targeting Prostatitis. It is currently in Approved.

Indications

Total Trials

Active Trials

292

Competitors

Pipeline

Status by Indication[3][1]

Indication

ProstatitisActive, not recruiting

Carpal Tunnel SyndromeActive, not recruiting

ArthritisActive, not recruiting

HepatitisActive, not recruiting

GlaucomaActive, not recruiting

Eye DiseaseActive, not recruiting

Dry Eye SyndromeActive, not recruiting

Interstitial CystitisActive, not recruiting

CataractActive, not recruiting

OsteoarthritisActive, not recruiting

ProstatitisPhase 3

Active, not recruiting

Carpal Tunnel SyndromePhase 1

Active, not recruiting

ArthritisPreclinical

Active, not recruiting

HepatitisPhase 1

Active, not recruiting

GlaucomaPreclinical

Active, not recruiting

Eye DiseasePhase 2

Active, not recruiting

Dry Eye SyndromePhase 3

Active, not recruiting

Interstitial CystitisPhase 2/Phase 3

Active, not recruiting

CataractPreclinical

Active, not recruiting

OsteoarthritisApproved

Active, not recruiting

Showing 10 of 11 indications

Competition

Competitive Landscape

778 competitors in Osteoarthritis

#DrugCompanyPhaseTrials

Sodium Hyaluronate

Sanofi

Approved

13 2

Ilaris

Novartis

Preclinical

2 3

Voltaren

CCerimon Pharmaceuticals

Preclinical

4 4

Bayer Aspirin

Enbrel

2 6

Glucophage

Boehringer Ingelheim

Preclinical

1 7

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Preclinical

1 8

Protonix

WWyeth-Lederle Vaccines

Preclinical

1 9

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

1 10

Paracetamol

GSK

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

N/ANot yet recruiting

Dry Eye

NCT06818487

Q2 2027

Phase 2/3Not yet recruiting

Osteoarthritis

NCT07337863

Q4 2027

Phase 1Recruiting

Alcohol

NCT05025865

Phase 1Recruiting

Hepatitis

NCT05018481

Q2 2028

Phase 1Not yet recruiting

Cystitis

NCT07665619

Clinical

Trials by Indication[1]

Osteoarthritis13 trials

Clinical Study of Pulp Mesenchymal Stem Cells in the Treatment of Primary Mild to Moderate Knee Osteoarthritis

Unknown status·CCAR-T (Shanghai) Biotechnology Co., Ltd.·Phase 1·NCT04130100·60 enrolled

Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis

Unknown status·PPhramongkutklao College of Medicine and Hospital·Phase 4·NCT06279507·176 enrolled

Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects

Unknown status·SShanghai AbelZeta Ltd.·Phase 2·NCT02855073·28 enrolled

Show 10 more trials

Prolotherapy Intervention Effect in Patient With Knee Osteoarthritis

Completed·HHasanuddin University·Phase 4·NCT04557943·36 enrolled

Efficacy of 3 Weekly Injections of Hyaluronate in Patients With Ankle Osteoarthritis

Completed·KKaohsiung Veterans General Hospital.·Phase 2·NCT00918736·46 enrolled

The Efficacy Study of Sodium Hyaluronate to Treat Symptomatic Hip Osteoarthritis

Terminated· Daiichi Sankyo logo

Daiichi Sankyo·Phase 3·NCT00330135·85 enrolled

Clinical Trial of Autologous Adipose Tissue-Derived Mesenchymal Progenitor Cells (MPCs) Therapy for Knee Osteoarthritis

Completed·SShanghai AbelZeta Ltd.·Phase 2·NCT02162693·53 enrolled

Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis

Recruiting·XXijing Hospital·N/A·NCT06082531·300 enrolled

The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients

Completed·TTRB Chemedica·Phase 2·NCT01267214·40 enrolled

A Phase II/III Randomized Double-Blind Multicenter Study Comparing UC-MSC-Derived Secretome and Sodium Hyaluronate in Patients With Knee Osteoarthritis

Not yet recruiting·UUniversitas Sriwijaya·Phase 2/3·NCT07337863·50 enrolled

Clinical Study of Artz in the Treatment of Knee Osteoarthritis

Unknown status·KKunming Baker Norton Pharmaceutical Sales Co., Ltd.·Phase 4·NCT02826031·300 enrolled

Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis

Recruiting·WWuxi Cellular Biopharmaceutical Group Ltd.·Phase 3·NCT06570291·520 enrolled

Medical Chitosan or Sodium Hyaluronate for Knee Osteoarthritis (CHOOSE)

Unknown status·SShanghai Qisheng Biological Preparation Co., Ltd.·Phase 4·NCT02323451·270 enrolled

Treatment2 trials

Effect of Various Treatment Modalities on Dendritic Vial Ulcer

Unknown status·SSohag University··NCT05313828·40 enrolled

Intra-articular Injection of MSCs in Treatment of Knee OA

Unknown status·—·Phase 2·NCT03028428·1 enrolled

Dry Eye2 trials

Ganyan-1 in Dry Eye

Not yet recruiting·—·N/A·NCT06818487·219 enrolled

Wireless Micropump in Dry Eye Patients

Unknown status·—·N/A·NCT04667819·20 enrolled

Carpal Tunnel Syndrome2 trials

Hyaluronic Acid Hydro-dissection Use in Idiopathic Carpal Tunnel Syndrome Guided by Ultrasonic Study

Completed·—·Phase 1·NCT03180125·80 enrolled

Combined Effect of Insulin and Sodium Hyaluronate Injection Guided by Ultrasound in Carpal Tunnel Syndrome

Unknown status·—·Phase 1·NCT04142411·90 enrolled

Eye Disease1 trial

A Phase II, Dose Ranging Study Of CP-690,550 Eye Drops In Patients With Dry Eye Disease

Completed· Pfizer logo

Pfizer·Phase 2·NCT01135511·285 enrolled

17 more indications

Dry Eye Syndrome1 trial

Safety and Efficacy Assessment of Vismed® (Sodium Hyaluronate) for the Treatment of Dry Eye Syndrome

Completed·LLantibio·Phase 3·NCT00599716·300 enrolled

Rotator Cuff Disease1 trial

Ultrasonography Guided Subacromial Sodium Hyaluronate Injection in Rotator Cuff Disease

Unknown status·IIsfahan University of Medical Sciences·Phase 2/3·NCT01735058·48 enrolled

Arthritis1 trial

A Validation Study of Sodium Hyaluronate in Patients With Periarthritis of Shoulder

Unknown status·PPeking University People's Hospital·N/A·NCT03365388·260 enrolled

Dry Eye Symptoms1 trial

Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms

Completed· AbbVie logo

AbbVie·Phase 4·NCT00761202·50 enrolled

Alcohol1 trial

HA35 Acute Alcohol Study

Recruiting·TThe Cleveland Clinic·Phase 1·NCT05025865·24 enrolled

Hepatitis1 trial

HA35 Moderate Alcoholic Hepatitis (AH) Study

Recruiting·TThe Cleveland Clinic·Phase 1·NCT05018481·54 enrolled

Interstitial Cystitis1 trial

Assessing the Effectiveness and Safety of Interferon Bladder Infusion for the Treatment of Interstitial Cystitis

Unknown status·WWest China Hospital·Phase 2/3·NCT05912946·129 enrolled

Injury1 trial

Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury

Unknown status·QQilu Hospital of Shandong University·Phase 1/2·NCT03955497·30 enrolled

Prospective1 trial

A Prospective Study of the Effect of Topical Sodium Hyaluronate Immediately Post-PKP on Time to Reepithelialization

Completed·UUniversity of Virginia·N/A·NCT00570648·50 enrolled

Cataract1 trial

Clinical Effects and Safety of 3% Diquafosol After Cataract Surgery

Completed·SSoonchunhyang University Hospital·N/A·NCT02608489·86 enrolled

Prostatitis1 trial

The Role of Butirprost® in Combination With Antibiotics in Chronic Bacterial Prostatitis (CBP) Treatment

Completed·FFederico II University·Phase 3·NCT06684626·60 enrolled

Glaucoma1 trial

Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma

Unknown status·MMahidol University·N/A·NCT01284439·120 enrolled

Pain1 trial

HUPS: Hyalgan Use in Painful Shoulder

Completed· Sanofi logo

Sanofi·Phase 3·NCT00377624·602 enrolled

Disc Degeneration1 trial

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

Completed·DDiscGenics, Inc.·Phase 1·NCT03347708·60 enrolled

Hyaluronic Acid1 trial

The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator

Unknown status·—·Phase 4·NCT00422643·60 enrolled

Cystitis1 trial

Clinical Efficacy of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Combined With Sodium Hyaluronate Intravesical Instillation in the Treatment of Radiation Cystitis

Not yet recruiting·FFujian Medical University Union Hospital·Phase 1·NCT07665619·48 enrolled

Unspecified1 trial

Exploratory Study of OPC-12759 Ophthalmic Suspension

Completed· Otsuka logo

Otsuka·Phase 2·NCT01493180·102 enrolled

Sources

References

[1]
ClinicalTrials.gov — 37 trial records for Sodium Hyaluronate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Sodium Hyaluronate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Sodium Hyaluronate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Sanofi company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Sanofi

Sodium Hyaluronate

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Q2 2027

Q4 2027

Q2 2028

Trials by Indication[1]

Osteoarthritis13 trials

Treatment2 trials

Dry Eye2 trials

Carpal Tunnel Syndrome2 trials

Eye Disease1 trial

Dry Eye Syndrome1 trial

Rotator Cuff Disease1 trial

Arthritis1 trial

Dry Eye Symptoms1 trial

Alcohol1 trial

Hepatitis1 trial

Interstitial Cystitis1 trial

Injury1 trial

Prospective1 trial

Cataract1 trial

Prostatitis1 trial

Glaucoma1 trial

Pain1 trial

Disc Degeneration1 trial

Hyaluronic Acid1 trial

Cystitis1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

Related News