Tegileridine

Phase 3Small molecule

XXin Chen

Tegileridine is one of 66 small molecule programs targeting Tracheal Intubation. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Tracheal IntubationNot yet recruiting

Nerve BlockNot yet recruiting

HysterectomyRecruiting

ScoliosisNot yet recruiting

Pain, PostoperativeRecruiting

Tracheal IntubationPreclinical

Not yet recruiting

Nerve BlockPreclinical

Not yet recruiting

HysterectomyPhase 3

Recruiting

ScoliosisPhase 3

Not yet recruiting

Pain, PostoperativePhase 3

Recruiting

Competition

Competitive Landscape

49 competitors in Hysterectomy

#DrugCompanyPhaseTrials

Toradol

Roche

Approved

2 2

Medrol

Pfizer

Approved

1 3

Atarax

Pfizer

Approved

1 4

Golytely

Bayer

Approved

1 5

MS Contin

HHikma Pharmaceuticals LLC

Approved

8 6

Marcaine

IInnocoll

Approved

8 7

Oxycontin

PProtega

Approved

6 8

Lyrica

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

5 9

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Approved

5 10

Xylocaine

MMEDRx USA, Inc.

Approved

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

PreclinicalNot yet recruiting

Tracheal Intubation

NCT07749131

N/ANot yet recruiting

Nerve Block

NCT07386626

Q1 2027

ApprovedRecruiting

Pain, Postoperative

NCT07412223

Q3 2027

Post-ApprovalNot yet recruiting

Scoliosis

NCT07229495

Clinical

Trials by Indication[1]

Post Operative Pain1 trial

Clinical Study on the Effect of Tegileridine on Postoperative Pain in Patients Undergoing Abdominal Surgery.

Completed·XXin Chen·Phase 4·NCT07277153·150 enrolled

Hysterectomy1 trial

Clinical Study of Equivalent Doses of Oxycodone or Tegileridine on Patients Undergoing Gynecological Laparoscopic Hysterectomy

Recruiting·XXin Chen·Phase 4·NCT07326683·92 enrolled

Nerve Block1 trial

Tegileridine Combined With Intercostal Nerve Block After Thoracoscopic Lung Resection

Not yet recruiting·TTongji Hospital·N/A·NCT07386626·118 enrolled

Efficacy and Safety1 trial

To Evaluate the Efficacy and Safety of Tegileridine and Oliceridine Injections in the Treatment of Postoperative Pain

Completed·YYuwei Qiu·Phase 4·NCT06458400·75 enrolled

Scoliosis1 trial

Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery

Not yet recruiting·PPeking Union Medical College Hospital·Phase 4·NCT07229495·171 enrolled

2 more indications

Tracheal Intubation1 trial

Determination of the 90% Effective Dose (ED90) of Tegileridine Fumarate for Inhibiting Hemodynamic Stress Response Induced by Tracheal Intubation During General Anesthesia: A Biased Coin Up-and-Down Sequential Study

Not yet recruiting·SShiyou Wei·Preclinical·NCT07749131·108 enrolled

Pain, Postoperative1 trial

Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery: A Multicenter, Randomized, Controlled Trial

Recruiting·XXiangya Hospital of Central South University·Approved·NCT07412223·152 enrolled

Sources

References

[1]
ClinicalTrials.gov — 7 trial records for Tegileridine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Tegileridine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Tegileridine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Xin Chen company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: XXin Chen

Tegileridine

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Q1 2027

Q3 2027

Trials by Indication[1]

Post Operative Pain1 trial

Hysterectomy1 trial

Nerve Block1 trial

Efficacy and Safety1 trial

Scoliosis1 trial

Tracheal Intubation1 trial

Pain, Postoperative1 trial

References

Drug Info

Quick Facts

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