Bupivacaine-fentanyl

PreclinicalSmall molecule

SSamuel Lunenfeld Research Institute, Mount Sinai Hospital

Bupivacaine-fentanyl is one of 62 small molecule programs targeting Caesarean Section. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Caesarean SectionCompleted

Postpartum DepressionActive, not recruiting

HypertensionActive, not recruiting

RecoveryCompleted

Caesarean SectionPreclinical

Completed

Postpartum DepressionPreclinical

Active, not recruiting

HypertensionPreclinical

Active, not recruiting

RecoveryPreclinical

Completed

Competition

Competitive Landscape

157 competitors in Hypertension

#DrugCompanyPhaseTrials

Baxfendy

AstraZeneca

Phase 3

3 2

Foundayo

Eli Lilly

Phase 3

3 3

Nitrostat

VViatris Specialty LLC

Phase 3

5 4

Minocycline /d

UUniversity of Florida

Phase 3

1 5

HCP1803-3

Hanmi Pharmaceutical Company Limited

Phase 3

1 6

SGLT2

PProf. Dr. med. Ingo Eitel

Phase 3

1 7

Avastin

Roche

Preclinical

1 8

Winrevair

Alphagan

Deltavit

HHyundai Pharmaceutical Co., LTD.

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Analgesia2 trials

Intrathecal Analgesia for Normal Labour

Unknown status·—·Phase 1·NCT04221568·70 enrolled

CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens

Completed·SSarah Beckley·Phase 4·NCT03117595·100 enrolled

Epidural Analgesia2 trials

Epidural Analgesia and Delivery of Second Twin

Completed·—··NCT04608006·124 enrolled

Effect of Epidural Analgesia on Burst Suppression

Unknown status·—·Phase 4·NCT05688449·64 enrolled

Erector Spinae Plane Block1 trial

Different Volumes of Erector Spinae Plane Block for Breast Surgery

Completed·MMedipol University·N/A·NCT05232084·40 enrolled

Pregnancy1 trial

Analgesia for 2nd Trimester Termination of Pregnancy

Terminated·SSamuel Lunenfeld Research Institute, Mount Sinai Hospital·N/A·NCT01563835·42 enrolled

Bupivacaine1 trial

Determination of the Effective Volume of 0.125% Bupivacaine-fentanyl 5mcg/mL in Labour Epidurals

Completed·SSamuel Lunenfeld Research Institute, Mount Sinai Hospital·N/A·NCT01972269·80 enrolled

12 more indications

NK Cell1 trial

Effects of Anesthetic Technique on NK Cells

Unknown status·—·N/A·NCT02669186·20 enrolled

Hypertension1 trial

Fractionated Vs Single Dose Injection for Spinal C-Section in Patients With Pregnancy-Induced Hypertension

Completed·IIndonesia University·N/A·NCT03693638·42 enrolled

Cesarean Section1 trial

Epidural Volume Extension and Intrathecal Use of Local Anesthetics in Cesarean Sections

Unknown status·UUniversity of Patras·Phase 2/3·NCT01558713·120 enrolled

Thoracotomy1 trial

Paravertebral Calcitonin in Thoracotomy

Active, not recruiting·TTanta University·N/A·NCT06330168·92 enrolled

Cesarean Delivery1 trial

Spinal Anesthesia for Cesarean Delivery: Bupivacaine With or Without Fentanyl

Completed·SSamuel Lunenfeld Research Institute, Mount Sinai Hospital·N/A·NCT00808327·140 enrolled

Lower Limb Orthopedic Surgery1 trial

Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients

Completed·KKasr El Aini Hospital·N/A·NCT04673812·92 enrolled

Induction of Labour1 trial

Preventive Analgesia in Multiparas Undergoing Induction of Labour

Completed·SSamuel Lunenfeld Research Institute, Mount Sinai Hospital·N/A·NCT00465231·16 enrolled

Postpartum Depression1 trial

CSE v. Epidural for Postpartum Depression

Completed·GGrace Lim, MD, MS·N/A·NCT03022526·61 enrolled

Cardiac Arrhythmia1 trial

Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method

Completed·MMedical University of Warsaw·Phase 4·NCT02988219·50 enrolled

Hip Arthroplasty1 trial

The Effect of Fascia Iliaca Compartment Block (FICB) on QoR-15 Score in Partial Hip Arthroplasty Surgery

Completed·UUnknown Sponsor·N/A·NCT05965544·60 enrolled

Caesarean Section1 trial

Intrathecal Bupivacaine-fentanyl and Bupivacaine-dexmedetomidine for Elective Low Segment Caesarean Section

Completed·—·N/A·NCT04095013·60 enrolled

Recovery1 trial

Can Different Intrathecal Drugs Affect Day Case Anal Surgery Recovery Duration?

Completed·—·N/A·NCT07156968·159 enrolled

Sources

References

[1]
ClinicalTrials.gov — 19 trial records for Bupivacaine-fentanyl. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Bupivacaine-fentanyl compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Bupivacaine-fentanyl. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Samuel Lunenfeld Research Institute, Mount Sinai Hospital company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: SSamuel Lunenfeld Research Institute, Mount Sinai Hospital

Bupivacaine-fentanyl

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Analgesia2 trials

Epidural Analgesia2 trials

Erector Spinae Plane Block1 trial

Pregnancy1 trial

Bupivacaine1 trial

NK Cell1 trial

Hypertension1 trial

Cesarean Section1 trial

Thoracotomy1 trial

Cesarean Delivery1 trial

Lower Limb Orthopedic Surgery1 trial

Induction of Labour1 trial

Postpartum Depression1 trial

Cardiac Arrhythmia1 trial

Hip Arthroplasty1 trial

Caesarean Section1 trial

Recovery1 trial

References

Drug Info

Quick Facts

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