Bupivicaine

ApprovedSmall molecule

TThomas Jefferson University

Bupivicaine is one of 120 small molecule programs targeting Ventral Hernia. It is currently in Approved.

Indications

Total Trials

Active Trials

119

Competitors

Pipeline

Status by Indication[3][1]

Indication

Ventral HerniaActive, not recruiting

Total Knee ArthroplastyActive, not recruiting

Breast CancerActive, not recruiting

MigraineActive, not recruiting

OsteoarthritisActive, not recruiting

ToothacheActive, not recruiting

Ventral HerniaPreclinical

Active, not recruiting

Total Knee ArthroplastyApproved

Active, not recruiting

Breast CancerPhase 2

Active, not recruiting

MigraineApproved

Active, not recruiting

OsteoarthritisPhase 3

Active, not recruiting

ToothachePhase 2

Active, not recruiting

Competition

Competitive Landscape

2828 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Bupivicaine

TThomas Jefferson University

Approved

1 2

Gemzar

GGynecologic Oncology Group

Preclinical

22 3

Zolymbus

AbbVie

Preclinical

1 4

Zinecard

CChildren's Oncology Group

Preclinical

2 5

Recentin

NNational Cancer Institute (NCI)

Preclinical

2 6

Cortef

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

1 7

Acupan

YYonsei University

Preclinical

1 8

Chantix

PPrism Pharmaceuticals

Preclinical

1 9

Avastin

Roche

Preclinical

4 10

Paracetamol

GSK

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Mastectomy2 trials

Magnesium Sulphate to Bupivicaine in Serratus Anterior Plane Block in Modified Radical Mastectomy

Unknown status·—·Phase 2/3·NCT04429893·80 enrolled

Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain

Unknown status·—·Phase 1/2·NCT02935933·90 enrolled

Total Knee Arthroplasty2 trials

Implementation of a Pain Management Protocol for Total Knee Arthroplasty

Completed·HHealth Sciences North Research Institute·Phase 4·NCT02474654·220 enrolled

A Trial Comparing Adductor Canal Catheter and Intraarticular Catheter Following Primary Total Knee Arthroplasty

Unknown status·TThomas Jefferson University·Phase 4·NCT02497911·110 enrolled

Breast Reconstruction1 trial

Pain Management Following TRAM Flap for Breast Reconstruction

Completed·MM.D. Anderson Cancer Center·N/A·NCT00500565·61 enrolled

Oncology1 trial

Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery

Completed·UUniversity of Wisconsin, Madison·Phase 2·NCT01444924·75 enrolled

Epidural Analgesia1 trial

Patient Controlled Epidural Analgesia Versus Continuous Epidural Infusion: Obstetrical and Neonatal Outcomes

Unknown status·MMemorialCare·N/A·NCT00810914·270 enrolled

10 more indications

Pain1 trial

Transversus Abdominis Plane (TAP) Block for Post Caesarian Pain

Withdrawn·NNew York Presbyterian Brooklyn Methodist Hospital·Phase 3·NCT01986049

Breast Cancer1 trial

Stellate Ganglion Block (SGB) For Women for Breast Cancer

Completed·NNorthwestern University·Phase 2·NCT02513329·37 enrolled

Sedation1 trial

Dexmedetomidine for Sedation in Total Knee Replacements

Completed·UUniversity of Saskatchewan·Phase 3·NCT02466022·54 enrolled

ART1 trial

Periarticular Injection Versus Popliteal Block

Enrolling by invitation·CCampbell Clinic·Phase 4·NCT04575688·100 enrolled

Femoral Nerve Block1 trial

Effectiveness of Continuous Femoral Nerve Block Versus Single Shot Femoral Nerve Block for Pain Control

Terminated·UUniversity of Colorado, Denver·N/A·NCT01916590·7 enrolled

Migraine1 trial

Greater Occipital Nerve Block for Migraine Prophylaxis

Completed·MMayo Clinic·Phase 4·NCT00915473·70 enrolled

Ventral Hernia1 trial

Bupivicaine to Reduce Postoperative Pain in Laparoscopic Ventral Hernia Repair

Unknown status·—·N/A·NCT01530815·80 enrolled

Toothache1 trial

Percocet vs. Bupivicaine for Toothaches in the ED

Terminated·SStony Brook University·Phase 2·NCT02862691·2 enrolled

Osteoarthritis1 trial

A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb

Completed·HHospital for Special Surgery, New York·Phase 3·NCT00398866·200 enrolled

Abdominal Surgery1 trial

A Pilot Study of Bupivacaine Infusion in Abdominal Surgery

Unknown status·MMargherita CADDEDU·Phase 2·NCT00280553·60 enrolled

Sources

References

[1]
ClinicalTrials.gov — 17 trial records for Bupivicaine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Bupivicaine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Bupivicaine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Thomas Jefferson University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: TThomas Jefferson University

Bupivicaine

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Mastectomy2 trials

Total Knee Arthroplasty2 trials

Breast Reconstruction1 trial

Oncology1 trial

Epidural Analgesia1 trial

Pain1 trial

Breast Cancer1 trial

Sedation1 trial

ART1 trial

Femoral Nerve Block1 trial

Migraine1 trial

Ventral Hernia1 trial

Toothache1 trial

Osteoarthritis1 trial

Abdominal Surgery1 trial

References

Drug Info

Quick Facts

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