Pethidine

ApprovedSmall molecule

KKasr El Aini Hospital

Pethidine is one of 100 small molecule programs targeting Stroke. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

StrokeActive, not recruiting

Adverse EffectActive, not recruiting

Inguinal HerniaActive, not recruiting

StrokePhase 3

Active, not recruiting

Adverse EffectPreclinical

Active, not recruiting

Inguinal HerniaPhase 2

Active, not recruiting

Competition

Competitive Landscape

461 competitors in Stroke

#DrugCompanyPhaseTrials

Pethidine

KKasr El Aini Hospital

Approved

1 2

Folvite

Eli Lilly

Preclinical

1 3

Zometa

Pfizer

Preclinical

1 4

Savella

AbbVie

Preclinical

1 5

Repatha

Amgen

Preclinical

—6

Botox

RRevance Therapeutics, Inc.

Preclinical

2 7

Alka-Seltzer

AAbbott

Preclinical

1 8

Periactin

CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Preclinical

1 9

Direct Anticoagulant

Bayer

Preclinical

3 10

Inderal

Mylan Pharmaceuticals Inc

Preclinical

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

Post-ApprovalNot yet recruiting

Sedation

NCT06736938

Q4 2027

N/ARecruiting

Adverse Effect

NCT07264309

Clinical

Trials by Indication[1]

Analgesia4 trials

Paracetamol for Intrapartum Analgesia

Unknown status·—·Phase 2·NCT02578251·104 enrolled

Hyoscine ButylBromide for Intrapartum Analgesia

Unknown status·—·Phase 2·NCT02557087·104 enrolled

Tenoxicam for Intrapartum Analgesia

Unknown status·—·Phase 2·NCT02549118·100 enrolled

Show 1 more trial

Pethidine Analgesia on Labor Duration

Completed·KKanuni Sultan Suleyman Training and Research Hospital··NCT03882814·240 enrolled

Erector Spinae Plane Block2 trials

Erector Spinae Plane Block in Scoliotic Adolescents

Completed·KKasr El Aini Hospital·Phase 2·NCT03968146·30 enrolled

Erector Spinae Plane Block Versus Quadratus Lumborum Block for Open Renal Surgeries in Children

Unknown status·—·Phase 4·NCT05386121·60 enrolled

Intraoperative1 trial

The Effect of Intraoperative Tramadol on Postoperative Opioid

Completed·MMansoura University·N/A·NCT05696886·400 enrolled

Inguinal hernia1 trial

Fascia Transversalis Versus Transversus Abdominis Plane Block for Children Undergoing Inguinal Hernia Surgery

Recruiting·KKasr El Aini Hospital·Phase 2·NCT06326944·50 enrolled

Intravenous Administration1 trial

Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs

Completed·—·Phase 4·NCT05284409·130 enrolled

12 more indications

Randomised Controlled Trial1 trial

A Randomised Controlled Trial of Remifentanil Intravenous Patient Controlled Analgesia (PCA) Versus Intramuscular Pethidine for Pain Relief in Labour

Completed·UUniversity of Birmingham·Phase 4·NCT02179294·401 enrolled

Adverse Effect1 trial

Combined Intravenous Tramadol and Paracetamol Versus Intramuscular Pethidine for Pain Relief During the First Stage of Labor. Compare the Efficacy and Adverse Effects

Recruiting·ZZohar Nachum·N/A·NCT07264309·140 enrolled

Stroke1 trial

Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke

Terminated·UUniversity of Erlangen-Nürnberg Medical School·Phase 3·NCT01833312·98 enrolled

Laparoscopic Cholecystectomy1 trial

Oblique Subcostal Tap Block Efficacy in Laparoscopic Cholecystectomy

Unknown status·IIuliu Hatieganu University of Medicine and Pharmacy·Phase 2/3·NCT02707250·120 enrolled

Surgery1 trial

Neuraxial Pethidine After Lumbar Surgery Trial

Unknown status·AAustin Health·Phase 3·NCT00163553·60 enrolled

Prevention1 trial

Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering

Unknown status·LLagos State Health Service Commission·Phase 2·NCT02441673·130 enrolled

Sedation1 trial

Balanced Analgosedation in Bronchoscopy: Propofol/Pethidine Versus Midazolam/Pethidine

Not yet recruiting·FFondazione Andrea Cesalpino Arezzo ONLUS·Phase 4·NCT06736938·530 enrolled

Pain After Surgery1 trial

Caudal Epidural Catheterization in Pediatric Renal Transplant: Effect on Hemodynamics and Pain After Surgery

Completed·—·N/A·NCT02037802·60 enrolled

Renal Transplant1 trial

Dual Transversus Abdominis Plane Block in Pediatric Renal Transplant: Effect on Pain Control

Completed·—·N/A·NCT02858622·44 enrolled

Oocyte Retrieval1 trial

A Non-inferiority Trial on Pain Relief During Oocyte Retrieval

Completed·KKwong Wah Hospital·Phase 4·NCT02494180·170 enrolled

Dexamethasone1 trial

Effect of Spinal Dexamethasone During Transuretheral Prostatectomy

Completed·—·Phase 2·NCT02619019·90 enrolled

Pain Control1 trial

Efficacy of Pethidine, Ketorolac And Xylocaine Gel As Analgesics For Pain Control In Shockwave Lithotripsy

Completed·MMansoura University·Phase 4·NCT03032458·165 enrolled

Sources

References

[1]
ClinicalTrials.gov — 21 trial records for Pethidine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Pethidine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Pethidine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Kasr El Aini Hospital company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: KKasr El Aini Hospital

Pethidine

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2027

Q4 2027

Trials by Indication[1]

Analgesia4 trials

Erector Spinae Plane Block2 trials

Intraoperative1 trial

Inguinal hernia1 trial

Intravenous Administration1 trial

Randomised Controlled Trial1 trial

Adverse Effect1 trial

Stroke1 trial

Laparoscopic Cholecystectomy1 trial

Surgery1 trial

Prevention1 trial

Sedation1 trial

Pain After Surgery1 trial

Renal Transplant1 trial

Oocyte Retrieval1 trial

Dexamethasone1 trial

Pain Control1 trial

References

Drug Info

Quick Facts

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