Cecon
(ascorbic acid)Small molecule
Ascorbic acid, also known as vitamin C, is used to prevent and treat vitamin C deficiency (scurvy) and to support immune system function. It's also used as a nutritional supplement to help with wound healing and overall health.[1]
0
Indications
99
Total Trials
15
Active Trials
0
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Ascorbic Acid7 trials
Ascorbic Acid Treatment in CMT1A Trial (AATIC)
Completed·—·Phase 2·NCT00271635·13 enrolled
Show 4 more trials
Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease
Withdrawn·—·Phase 2·NCT01125449
Lead Detoxifying Effects of Ascorbic Acid Among School Going Adolescents of Karachi- A Cluster Randomized Control Trial
Completed·—·Phase 2/3·NCT02745873·144 enrolled
Impact of Ascorbic Acid in the Prevention of Vancomycin Induced Nephrotoxicty
Unknown status·—·Phase 4·NCT03921099·40 enrolled
COVID-194 trials
Pancreatic Cancer4 trials
Show 1 more trial
Sepsis4 trials
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
Completed·—·Phase 2·NCT03422159·140 enrolled
Show 1 more trial
65 more indications
Acute Lung Injury2 trials
Role of Ascorbic Acid Infusion in Critically Ill Patients With Transfusion Related Acute Lung Injury
Completed·—·Phase 2·NCT04153487·40 enrolled
Atrial Fibrillation2 trials
Vascular Dysfunction2 trials
Targeting ER Stress in Vascular Dysfunction
Terminated·—·Phase 1·NCT04001647·17 enrolled
Post Operative Pain2 trials
Effect of Ascorbic Acid Final Flush on Post-operative Pain in Mandibular Molars.
Unknown status·—·N/A·NCT05478044·30 enrolled
Vitamin C Efficacy in Reducing Post Operative Pain
Completed·—·Phase 4·NCT01322061·80 enrolled
Complication2 trials
Septic Shock2 trials
Vitamin C Deficiency in Septic Shock
Completed·—·Phase 4·NCT06224881·150 enrolled
Prevention2 trials
Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries
Withdrawn·—·Phase 1·NCT04261036
Vitamin C for the Prevention of UTI in Women Who Undergo Elective GYN Surgeries
Withdrawn·—·Phase 1·NCT03800667
Multiple Myeloma2 trials
Effectiveness2 trials
Breast Cancer2 trials
Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer
Unknown status·—·Phase 1/2·NCT03175341·30 enrolled
Metastatic Colorectal Cancer1 trial
Lung Cancer1 trial
Pharmacological Ascorbate for Lung Cancer
Completed·—·Phase 2·NCT02420314·55 enrolled
End-Stage Renal Disease1 trial
Lung Transplant1 trial
Use of ARINA-1 in an Intermediate Size Patient Population of Bilateral Lung Transplant Patients With CLAD Grade 0
Completed·—·Phase 1·NCT03226431·6 enrolled
Intraoperative1 trial
Endothelial Dysfunction1 trial
Clinical Utility of Endothelial Dysfunction in PAD
Terminated·—·Phase 1·NCT00491751·108 enrolled
Non-Small Cell Lung Cancer1 trial
Acute Promyelocytic Leukemia1 trial
Kidney Cancer1 trial
Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery
Terminated·—·Phase 2·NCT03334409·5 enrolled
Critically Ill Patients1 trial
Hypertension1 trial
Oral Mucositis1 trial
Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers
Completed·PPanineeya Mahavidyalaya Institute of Dental Sciences & Research Centre·Phase 2/3·NCT02868151·180 enrolled
Drug1 trial
Efficacy and Safety1 trial
Colorectal1 trial
Urinary Tract Infection1 trial
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Recruiting·—·Phase 2·NCT05913180·180 enrolled
Insulin resistance1 trial
Fatigue1 trial
Cancer1 trial
Vitamin C as an Anti-cancer Drug
Completed·—·Phase 2·NCT01080352·31 enrolled
Oxidative Stress1 trial
Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes
Completed·—·N/A·NCT00845130·42 enrolled
Type 2 Diabetes1 trial
Hyperpigmentation1 trial
Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation
Completed·—·Phase 4·NCT03252418·10 enrolled
Ischemic stroke1 trial
Prevention and Treatment for Bruises in Patients with Ischemic Stroke
Not yet recruiting·—·Phase 4·NCT06823999·400 enrolled
Encephalopathy1 trial
Ascorbic Acid and Ibuprofen in Infants With Hypoxic Ischemic Encephalopathy
Completed·—·N/A·NCT00624871·60 enrolled
Psychosis1 trial
Function1 trial
Liver1 trial
Myelodysplastic Syndromes1 trial
TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid
Completed·—·Phase 2·NCT03397173·12 enrolled
Gingival Recession1 trial
Bladder Cancer1 trial
Renal insufficiency1 trial
Patients With Solid Tumors1 trial
Temporomandibular Joint Disorder1 trial
Anemia1 trial
Injury1 trial
VItamin C in Thermal injuRY: The VICToRY Trial
Suspended·—·Phase 3·NCT04138394·666 enrolled
Glucocorticoids1 trial
Blood Pressure1 trial
Effect of Low Doses of Vitamin C on Salivary Cortisol , Heart Rate , Blood Pressure During Group Presentation
Completed·—·Phase 4·NCT04135378·90 enrolled
Endothelial Function1 trial
Role of Endothelial Function in SCI CVD Risk
Recruiting·—··NCT06443151·60 enrolled
Carcinoma, Non-Small-Cell Lung1 trial
Regulatory
FDA Approval Timeline[3]
Oct 2, 2017
ASCOR
NDA NDA209112
Sources
References
- [1]
- [2]
- [3]
- [4]
Details
Drug Info
Quick Facts
- Modality
- Small molecule[2]
- Company
- MMcGuff Pharmaceuticals, Inc.