Ketofol

PreclinicalSmall molecule

TTanta University

Ketofol is one of 24 small molecule programs targeting Inguinal hernia. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Inguinal HerniaActive, not recruiting

Hemodynamic ResponseNot yet recruiting

Inguinal HerniaPreclinical

Active, not recruiting

Hemodynamic ResponsePreclinical

Not yet recruiting

Competition

Competitive Landscape

28 competitors in Inguinal Hernia

#DrugCompanyPhaseTrials

Marcaine

IInnocoll

Approved

4 2

Naropin

FFresenius Kabi USA, LLC

Approved

3 3

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Approved

3 4

Ancef

BBaxter Healthcare Corporation

Approved

1 5

Garamycin

SSchering-Plough

Approved

1 6

Iheezo

BB. Braun Medical Inc.

Approved

1 7

Advil

KKenvue Brands

Approved

1 8

Oxycontin

PProtega

Approved

1 9

Neurontin

VViatris Specialty LLC

Approved

1 10

Cymbalta

Jazz Pharmaceuticals

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2028

PreclinicalNot yet recruiting

Hemodynamic Response

NCT07783256

Clinical

Trials by Indication[1]

Sedation3 trials

Ketofol vs Propofol for Emergency Department Procedural Sedation and Analgesia

Completed·LLions Gate Hospital·Phase 3·NCT01211158·284 enrolled

Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography

Completed·PPost Graduate Institute of Medical Education and Research, Chandigarh·Phase 4·NCT02867930·50 enrolled

Ketofol Versus Fentofol for Procedural Sedation in the Pediatric Emergency Department

Completed·UUniversity of British Columbia·Phase 3·NCT02079090·30 enrolled

Propofol1 trial

Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy

Completed·—·N/A·NCT07273851·80 enrolled

Open Heart Surgery1 trial

Neuroprotection During Open Heart Surgery

Completed·Gghada fouad·Phase 3·NCT04486690·50 enrolled

Upper Gastrointestinal Endoscopy1 trial

Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy

Terminated·IIcahn School of Medicine at Mount Sinai·Phase 4·NCT02643979·22 enrolled

Delirium1 trial

Ketofol for Preventing Postoperative Delirium in Elderly Patients

Completed·ZZagazig University·Phase 4·NCT04816162·120 enrolled

6 more indications

Inguinal hernia1 trial

Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair

Unknown status·TTanta University·N/A·NCT05786833·60 enrolled

Premedication1 trial

Effect of Ketamine/Midazolam Premedication Versus Pre-extubation Ketofol on Recovery Profile in Pediatrics Undergoing Adenotonsillectomy.

Unknown status·—·Phase 4·NCT06010927·140 enrolled

Critically Ill1 trial

Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive Ventilation

Active, not recruiting·HHelwan University·Phase 3·NCT07530146·70 enrolled

Depression1 trial

A Prospective Randomized, Double Blind, Controlled, Safety and Non-inferiority Study of Esketamine Plus Propofol Compared to Methohexital Anesthesia for Electroconvulsive Therapy

Completed·MMedical University of Vienna·Approved·NCT05655754·56 enrolled

Hemodynamic Response1 trial

Effectiveness of Intravenous Ketodex Versus Ketofol for Obtunding Hemodynamic Responses to Laryngoscopy and Tracheal Intubation in Adult Elective Middle Ear Surgery Patients: A Prospective Randomized Comparative Study

Not yet recruiting·AAssiut University·Preclinical·NCT07783256·70 enrolled

Procedural Sedation1 trial

The Effect of Anesthesia Protocols Used in Gastrointestinal Endoscopy Procedures in Adolescents on the Outcome

Completed·GGiresun University··NCT07401914·90 enrolled

Sources

References

[1]
ClinicalTrials.gov — 13 trial records for Ketofol. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Ketofol compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Ketofol. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Tanta University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: TTanta University

Ketofol

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2028

Trials by Indication[1]

Sedation3 trials

Propofol1 trial

Open Heart Surgery1 trial

Upper Gastrointestinal Endoscopy1 trial

Delirium1 trial

Inguinal hernia1 trial

Premedication1 trial

Critically Ill1 trial

Depression1 trial

Hemodynamic Response1 trial

Procedural Sedation1 trial

References

Drug Info

Quick Facts

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