Deltasone

(Prednisolone)

ApprovedSmall molecule

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Prednisolone is a steroid medication used to reduce inflammation and suppress the immune system, helping treat conditions like autoimmune diseases, allergies, asthma, and certain cancers.[2] Deltasone is currently approved and in use across 159 indications[4].[1]

Deltasone is one of 1615 small molecule programs targeting Cardiomyopathy. It is currently in Approved.

159

Indications

371

Total Trials

Active Trials

1,614

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

CardiomyopathyRecruiting

Ocular HypertensionApproved

Allergic Bronchopulmonary AspergillosisRecruiting

SinusitisApproved

Eye InfectionApproved

Open-Angle GlaucomaApproved

Pure Red-Cell AplasiaApproved

Eczematoid DermatitisApproved

Allergic DiseaseApproved

HIV InfectionApproved

CardiomyopathyPhase 3

Recruiting

Ocular HypertensionApproved

Approved

Allergic Bronchopulmonary AspergillosisPhase 3

Recruiting

SinusitisApproved

Approved

Eye InfectionApproved

Approved

Open-Angle GlaucomaApproved

Approved

Pure Red-Cell AplasiaApproved

Approved

Eczematoid DermatitisApproved

Approved

Allergic DiseaseApproved

Approved

HIV InfectionApproved

Approved

Showing 10 of 157 indications

Competition

Competitive Landscape

401 competitors in Lymphoma

#DrugCompanyPhaseTrials

Deltasone

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

27 2

Zofran

Novartis

Preclinical

2 3

Cabenuva

GSK

Preclinical

1 4

Norvir

AbbVie

Preclinical

1 5

Emend

CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Preclinical

1 6

Kenalog

BBausch Health Americas, Inc.

Preclinical

1 7

Nuvigil

NNuvo Research GmbH

Preclinical

1 8

Elitek

AAzienda U.S.L. 1 di Massa e Carrara

Preclinical

—9

Decadron

QQuince Therapeutics S.p.A.

Systemic Therapy

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Post-ApprovalNot yet recruiting

Pulmonary Sarcoidosis

NCT06654934

N/AActive, not recruiting

Airway Disease

NCT00555607

Q1 2027

Phase 3Not yet recruiting

Hepatitis

NCT06956482

Q3 2027

Post-ApprovalRecruiting

Miscarriage

NCT05725512

Q1 2028

Post-ApprovalNot yet recruiting

Breast Disease

NCT06943482

Phase 2Recruiting

Crohn's Disease

NCT06953791

Clinical

Trials by Indication[1]

Lymphoma19 trials

Combination Chemotherapy in Treating Young Patients With Hodgkin's Lymphoma

Completed·CChristine Mauz-Körholz·Phase 3·NCT00433459·2,134 enrolled

Rituximab, Combination Chemotherapy, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed Follicular Non-Hodgkin Lymphoma

Terminated·UUniversity of Southampton·Phase 2·NCT00637832·1 enrolled

Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma

Recruiting·SStichting Hemato-Oncologie voor Volwassenen Nederland·Phase 3·NCT06220032·324 enrolled

Show 16 more trials

Nivolumab With Standard of Care Chemotherapy for Peripheral T Cell Lymphomas

Completed·UUniversity of Colorado, Denver·Phase 1/2·NCT03586999·18 enrolled

Combination Chemotherapy and/or Radiation Therapy in Treating Young Patients With Hodgkin's Lymphoma

Unknown status·CChildren's Cancer and Leukaemia Group·N/A·NCT00417014·358 enrolled

Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma

Completed·UUniversity College, London·Phase 3·NCT00678327·1,202 enrolled

Rituximab Plus Combination Chemotherapy in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma

Unknown status·LLymphoma Trials Office·Phase 1·NCT00031902

Study of Tazemetostat as Single Agent in Solid Tumors or B-cell Lymphomas and in Combination With Prednisolone in DLBCL

Completed·EEpizyme, Inc.·Phase 1/2·NCT01897571·400 enrolled

CHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma, Multicentre Phase II Study

Unknown status·RRoyal Marsden NHS Foundation Trust·Phase 2·NCT01719835·87 enrolled

TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma

Completed·CChildren's Oncology Group·Phase 3·NCT00002757·1,148 enrolled

Study of Combination of PIGEV Before Autologous Stem Cell Transplant in Patients With Hodgkin's Lymphoma

Unknown status·—·Phase 1·NCT01884428·24 enrolled

A Study of Polatuzumab Vedotin in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, and Prednisone in Participants With B-Cell Non-Hodgkin's Lymphoma

Completed· Roche logo

Roche·Phase 1/2·NCT01992653·85 enrolled

Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma

Unknown status·UUnited Kingdom Children's Cancer Study Group·Phase 3·NCT00003423·100 enrolled

Radiation Therapy or Combination Chemotherapy in Treating Young Patients With Hodgkin's Lymphoma

Unknown status·CChildren's Cancer and Leukaemia Group·N/A·NCT00416377·353 enrolled

Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma

Completed·UUniversity College, London·Phase 2·NCT00666484·47 enrolled

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma

Active, not recruiting·BBarbara Ann Karmanos Cancer Institute·Phase 2·NCT04479267·8 enrolled

Combination Chemotherapy in Treating Older Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma

Completed·CCancer Research Campaign Clinical Trials Centre·Phase 3·NCT00002576·200 enrolled

Combination Chemotherapy Plus Filgrastim in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma

Unknown status·LLymphoma Trials Office·Phase 1/2·NCT00032149·30 enrolled

Alemtuzumab and Combination Chemotherapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IV Peripheral T-Cell Lymphoma

Unknown status·CCancer Research UK·Phase 1·NCT00562068·30 enrolled

Acute Lymphoblastic Leukemia13 trials

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT02828358·78 enrolled

Ma-Spore ALL 2020 Study

Recruiting·NNational University Hospital, Singapore·Phase 2·NCT06336395·500 enrolled

Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

Unknown status·UUniversitätsklinikum Hamburg-Eppendorf·N/A·NCT00343369·550 enrolled

Show 10 more trials

Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia

Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00002700·392 enrolled

Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk Acute Lymphoblastic Leukemia

Withdrawn·CChildren's Oncology Group··NCT00900445

Applying Pediatric Regimens to Younger Adult Patients With Acute Lymphoblastic Leukemia (ALL)

Unknown status·JJapan Adult Leukemia Study Group·Phase 2·NCT00131053·120 enrolled

ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016

Recruiting·NNational Hospital Organization Nagoya Medical Center·Phase 2·NCT03286634·60 enrolled

Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL)

Completed·CChildren's Oncology Group·Phase 1·NCT03792256·12 enrolled

Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment

Completed·GGoethe University·Phase 3·NCT02881086·1,023 enrolled

Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia

Completed·DDutch Childhood Oncology Group·Phase 3·NCT00015873·350 enrolled

German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)

Completed·GGoethe University·Phase 4·NCT00198991·1,883 enrolled

Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma

Unknown status·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00003728·1,500 enrolled

Study of Imatinib-Combined Chemotherapy for BCR-ABL-Positive Acute Lymphoblastic Leukemia (ALL)

Completed·JJapan Adult Leukemia Study Group·Phase 2·NCT00130195·100 enrolled

Prednisolone11 trials

Clinical Study to Assess the Effects of SRT2104 and Prednisolone on Biomarkers in Blood in Healthy Volunteers

Completed· GSK logo

GSK·Phase 1·NCT00920660·20 enrolled

Prednisolone for Pain Reduction in Knee OA

Completed·UUniversity of Alexandria·Phase 4·NCT01619163·125 enrolled

A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT03198013·120 enrolled

Show 8 more trials

Prednisolone Urinary Excretion Kinetics

Withdrawn·UUniversity Hospital, Strasbourg, France··NCT05300490

Prednisolone Trial in Children Younger Than 4 Years

Completed·—·Phase 3·NCT03141970·170 enrolled

A Comparison of Two Different Single Doses of Prednisolone on Endodontic Inter-appointment Pain

Unknown status·KKing Saud University·Phase 2·NCT04481971·72 enrolled

Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in Humans

Completed·MMedical University of Vienna·Phase 4·NCT00312325·24 enrolled

Comparison Between Symbicort® and Prednisolone in COPD

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00259779·120 enrolled

Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae

Unknown status·MMashhad University of Medical Sciences·Phase 2·NCT00723268·30 enrolled

PREDnisolone-induced Beta-cell Dysfunction Prevented by EXenatide

Completed·AAmsterdam UMC, location VUmc·N/A·NCT00744224·8 enrolled

Comparison of Tofacitinib and Prednisolone in the Treatment of Active Takayasu's Arteritis

Unknown status·CChinese SLE Treatment And Research Group·Phase 3·NCT05749666·50 enrolled

Prostate Cancer7 trials

A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone in Participants With Prostate Cancer Who Have Received Docetaxel

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 2·NCT01795703·47 enrolled

A Study of Abiraterone Acetate in Metastatic Castration-Resistant Prostate Cancer Participants Who Responded Poorly to the First-line Combined Androgen Blockade Therapy

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 4·NCT02405858·51 enrolled

A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone in Participants With Prostate Cancer

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 2·NCT01756638·48 enrolled

Show 4 more trials

Dose Escalation Study With Cabazitaxel in Combination With Daily Prednisolone in Patients With Hormone Refractory Prostate Cancer

Completed· Sanofi logo

Sanofi·Phase 1·NCT01324583·48 enrolled

Evaluation of Safety of Cabazitaxel (Jevtana) in Patients With Metastatic Hormone Refractory Prostate Cancer

Completed· Sanofi logo

Sanofi·Phase 4·NCT02074137·10 enrolled

A Study of Abiraterone Acetate (JNJ-212082) and Prednisolone in Patients With Advanced Prostate Cancer

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 2·NCT01685983·82 enrolled

Study of Pembrolizumab (MK-3475) Plus Olaparib Versus Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-7339-010/KEYLYNK-010)

Completed· Merck & Co. logo

Merck & Co.·Phase 3·NCT03834519·793 enrolled

Rheumatoid Arthritis5 trials

Comparison of the Effectiveness of Two Different Dosages of Cortisone Compared to Placebo in Rheumatoid Arthritis

Completed·—·Phase 3·NCT02000336·395 enrolled

The Glucocorticoid Low-dose Outcome in RheumatoId Arthritis Study

Completed·AAmsterdam UMC, location VUmc·Phase 4·NCT02585258·451 enrolled

Very Low Dose Prednisolone on Newly Diagnosed Rheumatoid Arthritis

Not yet recruiting·—·Phase 4·NCT07252271·112 enrolled

Show 2 more trials

A Study To Investigate GW274150 Or Prednisolone In Rheumatoid Arthritis Taken Repeatedly For 28 Days.

Completed· GSK logo

GSK·Phase 2·NCT00379990·48 enrolled

A Single Dose Of Compound SB-681323 Compared To Prednisolone On A Protein That Is an Indicator For Rheumatoid Arthritis

Completed· GSK logo

GSK·Phase 2·NCT00134693·77 enrolled

108 more indications

Asthma5 trials

Assessment Of Disease Pathology And Key Therapeutic Targets In Severe Asthma

Terminated· GSK logo

GSK·Phase 1·NCT00327197·47 enrolled

Viral Inception of Asthma: Prospective Study From Infancy to School-age

Unknown status·UUniversity of Turku·N/A·NCT00731575·200 enrolled

Dexamethasone Versus Prednisolone in Acute Exacerbation of Childhood Asthma

Completed·MMuhammad Aamir Latif·N/A·NCT07275593·224 enrolled

Show 2 more trials

Use of Montelukast to Treat Children With Mild to Moderate Acute Asthma

Completed·TThe Hospital for Sick Children·Phase 2·NCT00213252·130 enrolled

EFFECTIVENESS OF SINGLE DOSE ORAL DEXAMETHASONE VERSUS MULTIDOSE PREDNISOLONE FOR TREATMENT OF ACUTE EXACERBATIONS OF ASTHMA AMONG CHILDREN ATTENDING THE EMERGENCY DEPARTMENT OF CHILDREN HOSPITAL, ISLAMABAD

Unknown status·DDR. MOHAMMAD ALI ARIF·N/A·NCT05850143·192 enrolled

Crohn's Disease4 trials

Top-down Infliximab Study in Kids With Crohn's Disease

Completed·EErasmus Medical Center·Phase 4·NCT02517684·100 enrolled

Efficacy of Infliximab in the Treatment of Patients Affected by Corticodependent Crohn's Disease (P02732)

Terminated· Merck & Co. logo

Merck & Co.·Phase 3·NCT00796250·9 enrolled

Exclusion Diet vs corticosteroIds in patientS With activE Crohn's Disease

Not yet recruiting·AAssistance Publique - Hôpitaux de Paris·Phase 2/3·NCT05284136·80 enrolled

Show 1 more trial

Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Patients

Recruiting·UUniversity Hospital Tuebingen·Phase 2·NCT06953791·52 enrolled

Hepatitis4 trials

A Safety and Efficacy Study of Mycophenolate Mofetil and Rilonacept in Patients With Alcoholic Hepatitis

Completed·SSouthern California Institute for Research and Education·Phase 2·NCT01903798·4 enrolled

PROlonged Corticosteroid Treatment or N-ACetylcysteine for Severe Alcoholic Hepatitis

Not yet recruiting·UUniversity Hospital, Lille·Phase 3·NCT06956482·477 enrolled

Efficacy of Monotherapy vs Combination Therapy of Corticosteroids With GCSF in Severe Alcoholic Hepatitis Patients.

Unknown status·IInstitute of Liver and Biliary Sciences, India·N/A·NCT04066179·126 enrolled

Show 1 more trial

Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH)

Completed· Gilead logo

Gilead·Phase 2·NCT02854631·104 enrolled

Corticosteroids4 trials

Corticosteroids in the Treatment of Tuberculous Pleurisy

Completed·GGuangxi Medical University·N/A·NCT00338793·1,500 enrolled

Treatment of Preschool Children With Upper Respiratory Tract Illnesses Using Azythromycin and Lower Respiratory Tract Symptoms Using Oral Corticosteroids.

Completed·MMilton S. Hershey Medical Center·Phase 3·NCT01272635·607 enrolled

Postoperative Oral Corticosteroids Following Tonsillectomy

Unknown status·WWayne State University·N/A·NCT03352115·200 enrolled

Show 1 more trial

Progression of HIV-Disease Under Low Dose Corticosteroids

Completed·MMedical Mission Institute, Germany·Phase 2·NCT01299948·326 enrolled

Chronic Obstructive Pulmonary Disease3 trials

Effects Of Oral Prednisolone On Bone Metabolism In Patients With Chronic Obstructive Pulmonary Disease

Completed· GSK logo

GSK·Phase 1·NCT00384306·9 enrolled

Prednisolone Novel Endpoint Study in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Completed· GSK logo

GSK·Phase 1·NCT00379730·90 enrolled

Study of SB681323 and Prednisolone on Biomarkers in COPD (Chronic Obstructive Pulmonary Disease) Patients

Completed· GSK logo

GSK·Phase 1·NCT00380133·20 enrolled

Diffuse Large B-Cell Lymphoma3 trials

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Cyclophosphamide, Doxorubicin, and Prednisone Plus Rituximab or Rituximab Biosimilar (Truxima) (R-CHP) in Participants With Diffuse Large B-Cell Lymphoma (DLBCL) (MK-2140-007)

Active, not recruiting· Merck & Co. logo

Merck & Co.·Phase 2·NCT05406401·60 enrolled

Multicentre Study to Determine the Cardiotoxicity of R-CHOP Compared to R-COMP in Patients With Diffuse Large B-Cell Lymphoma

Completed·AArbeitsgemeinschaft medikamentoese Tumortherapie·Phase 2·NCT00575406·94 enrolled

Gemcitabine Hydrochloride, Cyclophosphamide, Vincristine Sulfate, Prednisolone, and Rituximab in Treating Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma

Completed·UUniversity College, London·Phase 2·NCT00971763·62 enrolled

Steroid3 trials

Corticosteroid Reduction in COPD

Completed·CChronic Obstructive Pulmonary Disease Trial Network, Denmark·Phase 4·NCT02857842·318 enrolled

Barretts oEsophageal Resection With Steroid Therapy Trial

Withdrawn·PProfessor Michael Bourke·Phase 4·NCT02004782

Early Administration of Steroids in the Ambulance Setting

Completed·UUniversity of Florida·Phase 4·NCT03962894·834 enrolled

Nephrotic Syndrome3 trials

Comparison of Relapse Rate After 12 Weeks Verses 20 Weeks Steroid Therapy for the Management of First Episode of Steroid Sensitive Nephrotic Syndrome

Unknown status·SShaheed Zulfiqar Ali Bhutto Medical University·N/A·NCT04713410·68 enrolled

Study of Initial Steroid Treatment in Young Children With Nephrotic Syndrome

Withdrawn·—·Phase 3·NCT04536181

A Study to Evaluate the Effect of Tacrolimus and Corticosteroid Combination Therapy in Patients With Minimal Change Nephrotic Syndrome

Completed· Astellas logo

Astellas·Phase 4·NCT01763580·144 enrolled

Hypersensitivity Pneumonitis2 trials

"Randomized Controlled Trial Testing the Efficacy of Corticosteroid Therapy Versus Placebo in Fibrotic Hypersensitivity Pneumonitis"

Not yet recruiting·AAssistance Publique - Hôpitaux de Paris·Phase 3·NCT07210008·120 enrolled

An RCT of Mycophenolate Mofetil (MMF) in Fibrotic Hypersensitivity Pneumonitis

Unknown status·PPost Graduate Institute of Medical Education and Research, Chandigarh·Phase 4·NCT05626387·144 enrolled

Cataract2 trials

Study to Evaluate the Safety for the Treatment of Inflammation Associated With Cataract Surgery

Completed·IICON Bioscience Inc·Phase 3·NCT02547623·194 enrolled

A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms

Completed· AbbVie logo

AbbVie·Phase 4·NCT02028754·180 enrolled

Treatment2 trials

Acute Unilateral Vestibulopathy and Corticosteroid Treatment

Terminated·LLund University·Phase 4·NCT02912182·78 enrolled

Alipogene Tiparvovec for the Treatment of LPLD Patients

Withdrawn·UUniQure Biopharma B.V.·Phase 2·NCT02904772

Ulcerative Colitis2 trials

Study of COLAL-PRED® in the Treatment of Moderate Acute Ulcerative Colitis

Completed·AAlizyme·Phase 3·NCT00299013·796 enrolled

Conventional Step-Up Versus Infliximab Monotherapy in Patients With Ulcerative Colitis (P05553)

Terminated· Merck & Co. logo

Merck & Co.·Phase 3·NCT00984568·28 enrolled

Follicular Lymphoma2 trials

Study of MK-8808 for Participants With Follicular Lymphoma (MK-8808-001)

Terminated· Merck & Co. logo

Merck & Co.·Phase 1·NCT01370694·7 enrolled

Radiotherapy Versus Radiotherapy Plus Chemotherapy in Early Stage Follicular Lymphoma

Completed·TTrans Tasman Radiation Oncology Group·Phase 3·NCT00115700·150 enrolled

Oral Lichen Planus2 trials

A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus

Completed·—·Phase 4·NCT02587117·28 enrolled

Evaluation of Lycopene in the Treatment of Erosive Oral Lichen Planus

Completed·NNourhan M.Aly·Phase 2/3·NCT04652739·20 enrolled

Vasculitis2 trials

Anti-Cytokine Therapy for Vasculitis

Completed·UUniversity Hospital Birmingham NHS Foundation Trust·Phase 2·NCT00753103·37 enrolled

Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis

Unknown status·LLeiden University Medical Center·Phase 3·NCT03942887·100 enrolled

Erythema2 trials

Ciclosporin in the Management of New Erythema Nodosum Leprosum

Completed·LLondon School of Hygiene and Tropical Medicine·Phase 2·NCT00919542·12 enrolled

Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum

Completed·LLondon School of Hygiene and Tropical Medicine·Phase 2·NCT00919776·20 enrolled

Multiple Myeloma2 trials

Efficacy and Safety Study of SyB L-0501 for Patients With Multiple Myeloma

Terminated·SSymBio Pharmaceuticals·Phase 2·NCT01179490·5 enrolled

Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma

Unknown status·RRiverside Haematology Group·Phase 3·NCT00003603·660 enrolled

Leukemia2 trials

A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat

Withdrawn·CChildren's Oncology Group·Phase 1/2·NCT05320380

Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia

Unknown status·JJohann Wolfgang Goethe University Hospital·Phase 2·NCT00002531

Infantile Spasms2 trials

Prednisolone Versus Vigabatrin in the First-line Treatment of Infantile Spasms

Withdrawn·TThe Hospital for Sick Children·Phase 3·NCT02299115

Addition of Pyridoxine to Prednisolone in Infantile Spasms

Completed·LLady Hardinge Medical College·Phase 3·NCT01828437·62 enrolled

Hydrocortisone2 trials

Miracle Mouthwash Plus Hydrocortisone vs Prednisolone Mouth Rinse for Mouth Sores Caused by Everolimus

Completed·UUS Oncology Research·Phase 2·NCT02229136·104 enrolled

Ramadan Fasting in Patients With Corticotrope Deficiency Treated Either by Hydrocortisone or by Prednisolone

Completed·UUniversity Tunis El Manar·Phase 4·NCT03585829·53 enrolled

Hemangioma2 trials

Pulse Steroids Versus Oral Steroids in Problematic Hemangiomas of Infancy

Completed·TThe Hospital for Sick Children·Phase 3·NCT00312520·20 enrolled

Propranolol Versus Prednisolone for Treatment of Symptomatic Hemangiomas

Terminated·NNancy Bauman·Phase 2·NCT00967226·19 enrolled

Immune Thrombocytopenia2 trials

Newly Diagnosed Immune Thrombocytopenia Testing the Standard Steroid Treatment Against Combined Steroid & Mycophenolate

Completed·UUniversity Hospitals Bristol and Weston NHS Foundation Trust·Phase 3·NCT03156452·123 enrolled

Role of Eltrombopag as First Line Therapy in Primary Immune Thrombocytopenia.

Recruiting·RRenata PLC·Phase 1/2·NCT06531018·100 enrolled

Thrombocytopenia1 trial

Tacrolimus Plus Glucocorticoid for Severe Thrombocytopenia in SS

Unknown status·PPeking Union Medical College Hospital·Phase 2/3·NCT05694130·110 enrolled

Lupus Nephritis1 trial

Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis

Completed·GGenovate Biotechnology Co., Ltd.,·Phase 2·NCT02949349·32 enrolled

Glucocorticoid1 trial

Baricitinib Plus Glucocorticoid for Eosinophilia in IgG4-RD

Unknown status·WWen Zhang·N/A·NCT05781516·74 enrolled

Breast Cancer1 trial

Cyclophosphamide, Methotrexate, and Prednisolone With or Without Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer

Unknown status·NNational Cancer Centre, Singapore·Phase 2·NCT00687648·70 enrolled

Refractory1 trial

E3-Hormone Refractory Prostrate Cancer Taxotere Combination

Completed· Sanofi logo

Sanofi·Phase 2·NCT00498797·86 enrolled

Lenalidomide1 trial

Lenalidomide in Combination With CHOP in Patients With Untreated PTCL

Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 1/2·NCT04423926·91 enrolled

Safety and Efficacy1 trial

Multicenter Study of Safety and Efficacy Nivolumab at the Fixed Dose 40 mg (Nivo40) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed PMBL

Recruiting·NNational Research Center for Hematology, Russia·Phase 3·NCT06188676·100 enrolled

Mantle Cell Lymphoma1 trial

Combination Chemotherapy With or Without Bortezomib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Completed·UUniversity Hospital Plymouth NHS Trust·Phase 2·NCT00513955·50 enrolled

Glucocorticoids1 trial

Oral Glucocorticoids Effect on Post Endodontic Pain

Completed·—·Phase 4·NCT02819648·400 enrolled

Takayasu arteritis1 trial

A Study to Evaluate the Efficacy and Safety of Upadacitinib in Participants With Takayasu Arteritis (TAK)

Active, not recruiting· AbbVie logo

AbbVie·Phase 3·NCT04161898·56 enrolled

Colitis1 trial

Efficacy and Safety of Infliximab for Immune Checkpoint Inhibitor Induced Colitis

Recruiting·OOdense University Hospital·Phase 3·NCT05947669·195 enrolled

Wheezing1 trial

Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children

Unknown status·UUniversity of Turku·Phase 4·NCT00494624·300 enrolled

Dexamethasone1 trial

High Dose Dexamethasone Vs. Conventional Dose Prednisolone in Adult ITP

Completed·CCooperative Study Group A for Hematology·Phase 3·NCT00451594·157 enrolled

Adrenal insufficiency1 trial

Safety and Efficacy of Prednisolone in Adrenal Insufficiency Disease (PRED-AID Study)

Unknown status·IImperial College London·Phase 3·NCT03936517·44 enrolled

Chronic Lymphocytic Leukemia1 trial

Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia

Completed·LLeukemia Research Fund·Phase 3·NCT00004218

Pulmonary Sarcoidosis1 trial

Prednisolone for 12 Versus 6 Months to Treat Pulmonary Sarcoidosis

Not yet recruiting·PPost Graduate Institute of Medical Education and Research, Chandigarh·Phase 4·NCT06654934·100 enrolled

Kawasaki Disease1 trial

A Trial to Evaluate the Efficacy of Immunoglobulin Plus Steroid for Prevention of Coronary Artery Abnormalities in Taiwanese Refractory Kawasaki Disease (RAST Study)

Unknown status·NNational Taiwan University Hospital·Phase 3·NCT03200561·100 enrolled

Acute Leukemia1 trial

Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

Unknown status·DDutch Childhood Oncology Group·N/A·NCT00550992·445 enrolled

Adult Acute Lymphoblastic Leukemia1 trial

High-Dose Methotrexate (MTX) for Adult Acute Lymphoblastic Leukemia (ALL)

Unknown status·JJapan Adult Leukemia Study Group·Phase 3·NCT00131027·240 enrolled

Hemolytic Anemia1 trial

Prednisolone +/- Addition of Anti-CD20 Antibody, Rituximab, in Patients With Immune Hemolytic Anemia

Completed·—·Phase 3·NCT01134432·65 enrolled

Chronic Rhinosinusitis With Nasal Polyps1 trial

Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.

Unknown status·—·Phase 1/2·NCT05143502·60 enrolled

Acute1 trial

Acute Exacerbations Treated With BenRAlizumab (The ABRA Study)

Unknown status·UUniversity of Oxford·Phase 2·NCT04098718·158 enrolled

Lymphadenitis1 trial

Applying Shear Wave Elastography for Adjunct Steroid on Tuberculous Lymphadenitis

Unknown status·NNational Taiwan University Hospital·N/A·NCT05861440·50 enrolled

Advanced Stage1 trial

Bortezomib Plus CHOP Every 2 Weeks for Advanced Stage DLBCL

Completed·—·Phase 1/2·NCT00379574·49 enrolled

Breast Disease1 trial

Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease

Not yet recruiting·NNational University Hospital, Singapore·Phase 4·NCT06943482·40 enrolled

Antibody-Drug Conjugate1 trial

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

Recruiting· Eisai logo

Eisai·Phase 1/2·NCT04300556·182 enrolled

COVID-191 trial

Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19

Active, not recruiting·VValentina Puentmann·Phase 3·NCT05619653·279 enrolled

Insulin resistance1 trial

The Effect of Curcumin on the Development of Prednisolone-induced Hepatic Insulin Resistance

Terminated·UUniversity Hospital, Gentofte, Copenhagen·N/A·NCT04315350·24 enrolled

Chronic Graft Versus Host Disease1 trial

A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease.

Active, not recruiting· Sanofi logo

Sanofi·Phase 3·NCT06143891·260 enrolled

Headache1 trial

Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache

Completed·SSorlandet Hospital HF·Phase 3·NCT00135122·100 enrolled

Chronic Hepatitis1 trial

Prednisolone Priming Study in Patients With Chronic Hepatitis B

Unknown status·YYun-Fan Liaw·Phase 4·NCT00778596·160 enrolled

Cardiac Sarcoidosis1 trial

PET/MR Imaging In Patients With Cardiac Sarcoidosis

Completed·UUniversity of Edinburgh·N/A·NCT03705884·40 enrolled

Inflammation1 trial

Intraorbital Injection Versus Oral Steroid in Anterior Idiopathic Orbital Inflammation

Unknown status·IIran University of Medical Sciences·Phase 3·NCT03958344·120 enrolled

Lymphoblastic Lymphoma1 trial

Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma

Terminated·CChildren's Cancer and Leukaemia Group·Phase 3·NCT00275106·600 enrolled

Necrosis1 trial

Corticodependent or Corticoresistant Brain Radionecrosis After Radiotherapy for Brain Metastases

Recruiting·IInstitut Cancerologie de l'Ouest·Phase 3·NCT06471465·84 enrolled

Ascites1 trial

CASIMAS: Catumaxomab Safety Phase IIIb Study With Intraperitoneal Infusion in Patients With Malignant Ascites Due to Epithelial Cancers

Completed·NNeovii Biotech·Phase 3·NCT00822809·230 enrolled

Polymyalgia Rheumatica1 trial

A Trial of Prednisolone in Combination With SPI-62 in Participants With Polymyalgia Rheumatica (PMR)

Terminated·SSparrow Pharmaceuticals·Phase 1·NCT06281236·1 enrolled

Allergic Bronchopulmonary Aspergillosis1 trial

Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis

Completed·PPost Graduate Institute of Medical Education and Research, Chandigarh·Phase 2/3·NCT01621321·50 enrolled

Sepsis1 trial

The Effect of Moderate-Dose Steroid Therapy in Sepsis

Completed·TTC Erciyes University·Phase 4·NCT01275638·55 enrolled

Injury1 trial

Efficacy of N-acetylcysteine With or Without Steroids in Drug Induced Liver Injury

Terminated·IInstitute of Liver and Biliary Sciences, India·N/A·NCT02686385·4 enrolled

Pulpitis1 trial

Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis

Completed·UUniversity Hospital, Bordeaux·Phase 3·NCT02629042·5 enrolled

Psoriatic Arthritis1 trial

Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis

Unknown status·UUniversity of Erlangen-Nürnberg Medical School·Phase 3·NCT04610476·270 enrolled

IgA Nephropathy1 trial

Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy

Unknown status·SSun Yat-sen University·Phase 2/3·NCT02662283·75 enrolled

CAR1 trial

Pilocarpine Use After Kahook Goniotomy

Recruiting·MMontefiore Medical Center·Phase 3·NCT03933631·142 enrolled

Kaposiform Hemangioendothelioma1 trial

Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma

Completed·WWest China Hospital·Phase 2·NCT03188068·30 enrolled

Ankylosing Spondylitis1 trial

Prednisolone in Active Ankylosing Spondylitis (AS)

Unknown status·—·Phase 2/3·NCT00244166·75 enrolled

Bullous Pemphigoid1 trial

Efficacy and Safety of add-on Dapsone Versus add-on Methotrexate in Patients With Bullous Pemphigoid

Completed·—·Phase 4·NCT05984381·62 enrolled

Liver Transplant1 trial

Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation

Unknown status·AArmin Goralczyk·Phase 2·NCT00890253·29 enrolled

Duchenne Muscular Dystrophy1 trial

Historically Controlled Trial of Corticosteroids in Young Boys With Duchenne Muscular Dystrophy

Completed·WWashington University School of Medicine·Phase 2·NCT02167217·25 enrolled

Liver Disease1 trial

Evaluation of HepQuant SHUNT to Assess Liver Disease; Substudy Within GS-US-416-2124

Withdrawn·HHepQuant, LLC·Phase 1·NCT03087968

Miscarriage1 trial

Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages

Recruiting·LLeiden University Medical Center·Phase 4·NCT05725512·490 enrolled

Neoadjuvant Therapy1 trial

Neoadjuvant Therapy of Abiraterone Plus ADT for Intraductal Carcinoma of the Prostate

Unknown status·WWest China Hospital·Phase 2·NCT04736108·50 enrolled

Type 2 Diabetes1 trial

Study to Assess the Effect on Glucose Homeostasis of Two Dose Levels of AZD9567, Compared to Prednisolone, in Adults With Type 2 Diabetes

Completed· AstraZeneca logo

AstraZeneca·Phase 2·NCT04556760·46 enrolled

Natural Killer Cell1 trial

Effect of Prednisolone Treatment on Uterine Natural Killer Cells

Recruiting·—·Phase 3·NCT03902912·84 enrolled

ESS1 trial

4"S" - Seasonal Symptoms Suppression Study

Unknown status·AAssociation Asthma, Bulgaria·Phase 4·NCT02557269·60 enrolled

Adverse Effect1 trial

Adverse Effects of Glucocorticoid Therapy on Bone in Childhood Crohn's Disease

Unknown status·UUniversity Hospital Birmingham·Phase 4·NCT00609752·80 enrolled

Prospective1 trial

The PRIME Study: A Randomized, Controlled, Prospective Study

Recruiting·VVance Thompson Vision - MT·Phase 4·NCT04549935·20 enrolled

Atopic Dermatitis1 trial

Standardized Time- and Score-oriented Treatment of Moderate and Severe Atopic Dermatitis

Completed·TTechnische Universität Dresden·N/A·NCT00148746

Acupuncture1 trial

Prednisone and Acupuncture for the Treatment of Facial Neuritis: a Multiple Center, CER in China

Unknown status·XXijing Hospital·N/A·NCT01201642·1,800 enrolled

Facet Joint Syndrome1 trial

Platelet-rich Plasma Infiltration Versus Corticosteroid Infiltration (Prednisolone) in Treatment of Lumbar Facet Joint Syndrome

Completed·CCHU de Reims·N/A·NCT05105256·76 enrolled

Osteoarthritis1 trial

CRx-102 Osteoarthritis Multicenter Evaluation Trial

Terminated·ZZalicus·Phase 2·NCT00521989·279 enrolled

Obstructive Sleep Apnea1 trial

Oral Corticosteroids' Role in Pediatric Obstructive Sleep Apnea

Completed·HHotel Dieu de France Hospital·N/A·NCT06917768·87 enrolled

Mortality1 trial

Comparison Between Prednisolone and Dexamethasone on Mortality in Patients on Oxygen Therapy, with CoViD-19

Completed·HHôpital NOVO·Phase 3·NCT04765371·89 enrolled

ART1 trial

Long-term Access Program (LAP) of Mepolizumab for Subjects Who Participated in Study MEA115921

Completed· GSK logo

GSK·Phase 3·NCT03298061·100 enrolled

Leprosy1 trial

Ciclosporin in the Management of New Type 1 Reactions in Leprosy

Completed·LLondon School of Hygiene and Tropical Medicine·Phase 2/3·NCT00919815·73 enrolled

Advanced Cancer1 trial

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT04071262·6 enrolled

Adverse Drug Reactions1 trial

Evaluation of TNF-α Blockade Effect in Patients With Severe Cutaneous Adverse Drug Reactions

Completed·—·N/A·NCT01276314·135 enrolled

Tic Disorder1 trial

Prednisolone Addition for Patients With Recent-onset Psychotic Disorder

Terminated·UUMC Utrecht·Phase 4·NCT02949232·42 enrolled

Complication1 trial

Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair

Terminated·FFrancis Schneck·N/A·NCT02162810·28 enrolled

Stroke1 trial

High Dose Steroids in Children With Stroke

Recruiting·IInsel Gruppe AG, University Hospital Bern·Phase 3·NCT04873583·70 enrolled

Methotrexate1 trial

Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy

Terminated·JJawaharlal Institute of Postgraduate Medical Education & Research·Phase 3·NCT02930343·136 enrolled

Langerhans Cell Histiocytosis1 trial

Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis

Completed·HHistiocyte Society·N/A·NCT00276757·376 enrolled

Fluorescence1 trial

Impact of Systemic Corticosteroid Therapy on Lens Transparency and Quantification of Lens Autofluorescence.

Completed·UUniversity Hospital, Clermont-Ferrand·N/A·NCT00337623·22 enrolled

Tuberculosis1 trial

Tuberculosis in HIV Infected Patients in Uganda

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00057421·190 enrolled

Hodgkin's Disease1 trial

Combination Chemotherapy Given With Radiation Therapy or Radiation Therapy Alone in Treating Patients With Early-Stage Hodgkin's Disease

Unknown status·MMedical Research Council·Phase 3·NCT00002987·400 enrolled

Single Ascending Dose1 trial

A Single Ascending Dose Study To Assess The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of AZD9567.

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT02512575·72 enrolled

Airway Disease1 trial

Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease

Active, not recruiting·KKarolinska Institutet·N/A·NCT00555607·233 enrolled

Circadian Rhythm1 trial

CIRcadian Rhythms and CortisoL. Effects on Substrate Metabolism and Clock Gene Expression and Functioning

Completed·UUniversity of Aarhus·N/A·NCT06035081·10 enrolled

Renal Transplant Recipients1 trial

Study Comparing Efficacy and Safety of Mycophenolate Mofetil (Cellcept) With Delayed Introduction of Sirolimus and Discontinuation of Cyclosporine, With Those of Mycophenolate Mofetil and Long Term Continuation of Cyclosporine in Renal Transplant Recipients

Completed· Roche logo

Roche·Phase 3·NCT02686619·237 enrolled

Friedreich ataxia1 trial

A Study of ASP2016 in Adults Who Have Heart Disease Associated With Friedreich Ataxia

Withdrawn· Astellas logo

Astellas·Phase 1·NCT06483802

Pericarditis1 trial

A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis

Completed·UUniversity of Cape Town·Phase 3·NCT00810849·1,400 enrolled

Renal Transplant1 trial

Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant Patients

Completed·NNational Taiwan University Hospital·Phase 4·NCT02077556·14 enrolled

Glycogen Storage Disease1 trial

A Study of Adeno-Associated Virus Serotype 8-Mediated Gene Transfer of Glucose-6-Phosphatase in Patients With Glycogen Storage Disease Type Ia (GSDIa)

Completed· Ultragenyx logo

Ultragenyx·Phase 3·NCT05139316·49 enrolled

Bone Disease1 trial

Identifying Individuals At Risk of Glucocorticoid-Induced Impairment of Bone Disease

Recruiting·OOdense University Hospital·Phase 2·NCT06421597·36 enrolled

Mycoplasma pneumoniae pneumonia1 trial

Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia

Unknown status·SSeoul National University Hospital·Phase 4·NCT02618057·80 enrolled

Unspecified3 trials

Velcade (Bortezomib) Consolidation After Transplant

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 3·NCT01539083·256 enrolled

The Electroretinogram in Healthy and Glucose Intolerant Young Men

Completed·GGlostrup University Hospital, Copenhagen·N/A·NCT01140932·10 enrolled

Phase I Methodology Study to Validate the Cantharidin Blister Model in Healthy Volunteers

Completed· GSK logo

GSK·Phase 1·NCT01762787·40 enrolled

Regulatory

FDA Approval Timeline[5]

Jan 1, 1982

STERANE

NDA NDA011446

Jan 1, 1982

HYDELTRASOL

NDA NDA011028

Jan 1, 1982

ECONOPRED

NDA NDA017468

Jan 1, 1982

OMNIPRED

NDA NDA017469

Jan 1, 1982

PRED FORTE

NDA NDA017011

Jan 1, 1982

PRED MILD

NDA NDA017100

Jan 1, 1982

DELTA-CORTEF

NDA NDA009987

Jan 1, 1982

METI-DERM

NDA NDA010209

Jan 1, 1982

STERANE

NDA NDA009996

Jan 1, 1982

HYDELTRASOL

NDA NDA011583

Jan 1, 1982

METICORTELONE

NDA NDA010255

May 28, 1986

PEDIAPRED

NDA NDA019157

Jun 1, 2006

ORAPRED ODT

NDA NDA021959

Jan 17, 2008

FLO-PRED

NDA NDA022067

Sources

References

[1]
ClinicalTrials.gov — 371 trial records for Prednisolone. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Deltasone drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — Prednisolone compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for Prednisolone. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA022067). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Deltasone. U.S. Food & Drug Administration.
[7]
SEC EDGAR — Pfizer's Upjohn has merged with Mylan to form Viatris Inc. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Glucocorticoid Receptor Agonist[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Patent Landscape[6]

Patent Cliff

Oct 11, 2028

Earliest patent expiration — generic entry possible after this date

Patent #Expires

7799331Oct 11, 2028