Active comparator

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Pancreatic CancerFibromyalgiaRotator Cuff Tear

335 competitors in Pancreatic Cancer

#DrugCompanyPhaseTrials

1

Medrol

Pfizer

Preclinical

12

Byetta

AstraZeneca

Preclinical

13

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

14

Ayvakit Sprinkle

MMemorial Sloan Kettering Cancer Center

Preclinical

15

Xylocaine

MMEDRx USA, Inc.

Preclinical

16

Feraheme

AAzurity Pharmaceuticals

Preclinical

17

Sulfonylureas

Eli Lilly

Preclinical

18

HS-20093

Jiangsu Hansoh Pharmaceutical Co., Ltd.

Preclinical

19

Hyperpolarized 13c Pyruvate

UUniversity of Maryland, Baltimore

Preclinical

110

PEG-Rhg-CSF

CCSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Preclinical

1Show 32 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

COVID-194 trials

Immuno-bridging Study of COVID-19 Protein Subunit Recombinant Vaccine

Completed·PPT Bio Farma·Phase 3·NCT05433285·4,050 enrolled

COVID-19 Paediatric VLA2001-321 Study

Withdrawn·VValneva Austria GmbH·Phase 2/3·NCT05298644

Omega-3, Nigella Sativa, Indian Costus, Quinine, Anise Seed, Deglycyrrhizinated Licorice, Artemisinin, Febrifugine on Immunity of Patients With (COVID-19)

Completed·—·Phase 2/3·NCT04553705·150 enrolled

Show 1 more trial

Booster Study of COVID-19 Protein Subunit Recombinant Vaccine

Completed·PPT Bio Farma·Phase 2·NCT05525208·696 enrolled

Influenza2 trials

A Study of mRNA-1020 and mRNA-1030 Seasonal Influenza Vaccines in Healthy Adults

Completed·Moderna·Phase 1/2·NCT05333289·572 enrolled

A Study of mRNA-1010 Seasonal Influenza Vaccine in Healthy Adults

Completed·Moderna·Phase 1/2·NCT04956575·885 enrolled

Rheumatoid Arthritis2 trials

A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)

Completed·AAsahi Kasei Pharma Corporation·Phase 2·NCT00902369·130 enrolled

A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)

Completed·AAsahi Kasei Pharma Corporation·Phase 2·NCT01285752·240 enrolled

Venous thrombosis1 trial

Oral Rivaroxaban in Children With Venous Thrombosis

Completed·Bayer·Phase 2·NCT01684423·64 enrolled

Gastritis1 trial

Clinical Study of Manpixiao in the Treatment of Chronic Atrophic Gastritis

Unknown status·—·Phase 1·NCT05493124·180 enrolled

40 more indications

Insomnia1 trial

SM-1 vs. an Active Comparator in A Model of Transient Insomnia

Not yet recruiting·SSequential Medicine Ltd·Phase 2·NCT04396327·14 enrolled

Actinic Keratosis1 trial

Safety, Tolerability, and Efficacy Study of LFX453 in Actinic Keratosis Patients

Completed·Novartis·Phase 2·NCT02404389·82 enrolled

Safety and Efficacy1 trial

Safety and Efficacy of Oral BT-11 in Crohn's Disease Patients With Moderate to Severe Disease

Withdrawn·NNImmune Biopharma·Phase 2·NCT05057273

Chlorhexidine1 trial

Irritation and Sensitization of Chlorhexidine Gluconate (CHG) Cloth

Completed·MMedline Industries·Phase 3·NCT02224625·249 enrolled

Rotator Cuff Tear1 trial

Perioperative Polmacoxib Reduce Opioid Consumption for Post Operative Pain After Rotator Cuff Tear.

Recruiting·EEulji University Hospital·N/A·NCT06590714·150 enrolled

Acute Myeloid Leukemia1 trial

GOELAMS SA4 Study: the Role of Fludarabine in the Treatment of Acute Myeloid Leukemia in the Elderly

Completed·FFrench Innovative Leukemia Organisation·Phase 3·NCT00925873·303 enrolled

Non-Small Cell Lung Cancer1 trial

ARCHER 1009 : A Study Of Dacomitinib (PF-00299804) Vs. Erlotinib In The Treatment Of Advanced Non-Small Cell Lung Cancer

Completed·Pfizer·Phase 3·NCT01360554·878 enrolled

Fabry Disease1 trial

Evaluate the Safety and Efficacy of Fabagal® (Agalsidase Beta) in Patients With Fabry Disease

Recruiting·IISU Abxis Co., Ltd.·Phase 3·NCT06081062·24 enrolled

Clinical Trial1 trial

A Clinical Trial to Compare Safety and Pharmacokinetic Characteristics of CKD-337

Completed·Chong Kun Dang Pharmaceutical·Phase 1·NCT03346187·60 enrolled

Treatment1 trial

Ketamine, SGB and Combination Treatment for TBI

Recruiting·NNorthwestern University·Phase 2·NCT06608277·175 enrolled

Morphine1 trial

Staccato Apomorphine Single and Multi Dose PK

Completed·AAlexza Pharmaceuticals, Inc.·Phase 1·NCT03822364·56 enrolled

Total Hip Arthroplasty1 trial

Quadratus Lumborum Block for Total Hip Arthroplasty

Recruiting·UUniversity of California, Los Angeles·Phase 1·NCT05247255·80 enrolled

COPD1 trial

A Safety, Pharmacokinetic and Pharmacodynamic Study of PUR0200 in COPD Patients

Completed·PPulmatrix Inc.·Phase 1·NCT01921712·38 enrolled

Total Knee Replacement1 trial

Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?

Completed·NNew Lexington Clinic·N/A·NCT00492973·101 enrolled

Type 1 Diabetes1 trial

Efficacy & Safety of Inhaled Insulin in Type 1 Diabetes

Completed·MMannkind Corporation·Phase 3·NCT00308308·589 enrolled

Adult1 trial

Bioavailability of DFN-15 at 3 Different Doses vs. Comparator and to Determine Dose-proportionality of DFN-15 in Fasting Healthy Adults

Completed·—·Phase 1·NCT03051685·16 enrolled

Eye Disease1 trial

A Study to Evaluate the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease

Completed·AAramis Biosciences, Inc.·Phase 2·NCT05238597·207 enrolled

Low Dose Radiotherapy1 trial

Low Dose Radiotherapy Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Stage II-III NSCLC

Recruiting·—·Phase 2·NCT06714708·86 enrolled

Dermatitis1 trial

Green Banana Peel Extract for Stasis Dermatitis Treatment

Completed·UUniversidade do Vale do Sapucai·Phase 1·NCT06427733·20 enrolled

Sedation1 trial

Use of Dexmedetomidine for Deep Sedation in Patients Undergoing Outpatient Hysteroscopic Surgery

Terminated·NNorthwestern University·N/A·NCT01337739·8 enrolled

Radiotherapy1 trial

Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRC

Not yet recruiting·ZZhejiang Cancer Hospital·Phase 1/2·NCT06195670·220 enrolled

Whitening1 trial

Intraoral Appliance (IOA) Model Evaluating the Efficacy of a Whitening Toothpaste

Completed·CChurch & Dwight Company, Inc.·N/A·NCT07419685·31 enrolled

Allergic Rhinitis1 trial

Clinical Trial to Evaluate the Safety and Efficacy of AGR Tablet as a Treatment of Perennial Allergic Rhinitis in Korean

Completed·Ahn-Gook Pharmaceuticals Co.,Ltd·Phase 3·NCT01982916·324 enrolled

Clostridioides difficile Infection1 trial

Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection

Completed·CCrestone, Inc·Phase 2·NCT04781387·43 enrolled

Pancreatic Cancer1 trial

Epidemiological Assessment of the Risk for Pancreatic Cancer Associated With the Use of Semaglutide in Patients With Type 2 Diabetes - A Cohort Study Based on Nordic Registry Data

Unknown status·Novo Nordisk··NCT04572165·600,000 enrolled

SARS-CoV-21 trial

Phase 2b/3 Trial of VSV-ΔG SARS-CoV-2 Vaccine (BRILIFE) Against Approved Comparator Vaccine.

Withdrawn·NNeuroRx, Inc.·Phase 2/3·NCT04990466

Cachexia1 trial

Phase 2 Cachexia Clinical Trial to Evaluate the Efficacy and Safety of ASCA101

Not yet recruiting·MMetaFines·Phase 2·NCT07168226·135 enrolled

Narcolepsy1 trial

A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator in Adult Participants With Narcolepsy Type 1

Completed·Eisai·Phase 1·NCT06462404·22 enrolled

Chronic Obstructive Pulmonary Disease1 trial

A Study To Examine The Safety, Pharmacokinetics And Pharmacodynamics Of PF-03635659 In Patients With Chronic Obstructive Pulmonary Disease

Completed·Pfizer·Phase 2·NCT01033487·22 enrolled

Helicobacter Pylori1 trial

ERADICATE Hp2 - Treating Helicobacter Pylori With RHB-105 Compared to Active Comparator

Completed·RRedHill Biopharma Limited·Phase 3·NCT03198507·455 enrolled

Tics1 trial

A First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM12470

Completed·Hanmi Pharmaceutical Company Limited·Phase 1·NCT02302443·100 enrolled

Double-blind1 trial

Randomized, Double-blind Study to Evaluate the Tolerability of 2 Different Titration Methods of Rivastigmine Patch in AD Patients (MMSE 10-20)

Completed·Novartis·Phase 3·NCT01614886·216 enrolled

Fibromyalgia1 trial

ESKETamine for FIBromyalgia Treatment

Terminated·GGrand Hôpital de Charleroi·N/A·NCT04436250·23 enrolled

Immunogenicity1 trial

Safety and Immunogenicity of SARS-CoV-2 Protein Subunit Recombinant Vaccine in Healthy Children

Completed·PPT Bio Farma·Phase 3·NCT05546502·1,050 enrolled

Gingivitis1 trial

The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis

Completed·CColgate Palmolive·Phase 2·NCT02243046·162 enrolled

Efficacy1 trial

Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste

Completed·CChurch & Dwight Company, Inc.·N/A·NCT07419763·30 enrolled

Kidney Cancer1 trial

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Recruiting·SSWOG Cancer Research Network·Phase 3·NCT04510597·364 enrolled

SGLT2 Inhibitors1 trial

Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)

Active, not recruiting·OOhio State University··NCT07188545·23,280,000 enrolled

Psoriatic Arthritis1 trial

A Multi-Center, Randomized, Double-Blind, Placebo- and Active-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Zasocitinib (TAK-279) in Subjects With Active Psoriatic Arthritis Who Are Naïve to Biologic Disease-Modifying Antirheumatic Drugs (LATITUDE-PsA-3001)

Recruiting·Takeda·Phase 3·NCT06671483·1,088 enrolled

Unspecified1 trial

CT 327 in the "Atopy Patch Test" Model

Withdrawn·CCreabilis SA·Phase 1·NCT01368315·20 enrolled

Details

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