Hyperbaric bupivacaine

ApprovedSmall molecule

Hyperbaric bupivacaine is one of 92 small molecule programs targeting Total Knee Arthroplasty. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Total Knee ArthroplastyActive, not recruiting

Total Hip ArthroplastyActive, not recruiting

Cesarean SectionActive, not recruiting

Total Knee ArthroplastyPreclinical

Active, not recruiting

Total Hip ArthroplastyApproved

Active, not recruiting

Cesarean SectionPhase 2

Active, not recruiting

Competition

Competitive Landscape

275 competitors in Total Knee Arthroplasty

#DrugCompanyPhaseTrials

Hyperbaric bupivacaine

TTanta University

Approved

1 2

Cymbalta

Alnylam Pharmaceuticals

Preclinical

5 3

Lyrica

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

7 4

Xarelto

WWim Janssens

Preclinical

5 5

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Preclinical

4 6

Sufenta

LLeaf Vertical Inc.

Preclinical

3 7

EXPAREL

Pacira Pharmaceuticals, Inc

Preclinical

7 8

Xylocaine

MMEDRx USA, Inc.

Preclinical

2 9

Nucynta

CCollegium Pharmaceutical, Inc.

Preclinical

2 10

Zanaflex

LLegacy Health System

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Cesarean Section3 trials

Two Syringe Spinal Anesthesia Technique for Cesarean Section: A Simple Way to Achieve More Satisfactory Block and Less Hypotension

Completed·—·N/A·NCT02577432·124 enrolled

Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia

Completed·—·Phase 2·NCT02622126·60 enrolled

Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia

Completed·—·Phase 3·NCT02973048·40 enrolled

Labor Analgesia1 trial

Intrathecal Hydromorphone for Labor Analgesia

Terminated·—·N/A·NCT02277782·21 enrolled

Bupivacaine1 trial

ED90 of 0.75% Bupivacaine for Bilateral Tubal Ligation (BTL)

Withdrawn·—·Phase 4·NCT05017584